{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T20:33:04Z","timestamp":1791837184606,"version":"4.3.4"},"reference-count":28,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2010,5,12]],"date-time":"2010-05-12T00:00:00Z","timestamp":1273622400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>The reactions of selected \u03b1,\u03b2-unsaturated steroidal ketones with Lawesson\u2019s reagent (LR) in CH2Cl2 and toluene under the standard reaction conditions and with a combination of phosphorus pentasulfide with hexamethyldisiloxane (P4S10\/HMDO) in 1,2-dichlorobenzene (ODCB) under microwave irradiation were investigated and for this purpose several cholestane, androstane and pregnane carbonyl derivatives were chosen. Depending on the reagent and the solvent, 19 new sulfur containing compounds, including dithiones 4c and 4d, \u03b1,\u03b2-unsaturated 3-thiones 3a-e, dimer-sulfides 2a-e, 1,2,4-trithiolanes 5a-e and phosphonotrithioates 6b-e were synthesized. All newly prepared compounds were characterized by IR, 1H- and 13C-NMR spectroscopy and elemental analysis.<\/jats:p>","DOI":"10.3390\/molecules15053462","type":"journal-article","created":{"date-parts":[[2010,5,12]],"date-time":"2010-05-12T11:04:38Z","timestamp":1273662278000},"page":"3462-3477","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Thionation of Some \u03b1,\u03b2-Unsaturated Steroidal Ketones"],"prefix":"10.3390","volume":"15","author":[{"given":"Natalija M.","family":"Krsti\u0107","sequence":"first","affiliation":[{"name":"Center for Chemistry, Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Studentski trg 12-16, P. O. Box. 473, 11001 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mira S.","family":"Bjelakovi\u0107","sequence":"additional","affiliation":[{"name":"Center for Chemistry, Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Studentski trg 12-16, P. O. Box. 473, 11001 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milan M.","family":"Dabovi\u0107","sequence":"additional","affiliation":[{"name":"Center for Chemistry, Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Studentski trg 12-16, P. O. Box. 473, 11001 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir D.","family":"Pavlovi\u0107","sequence":"additional","affiliation":[{"name":"Faculty of Chemistry, University of Belgrade, Student ski trg 12-16, P. O. Box 158, 11001 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2010,5,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.steroids.2007.02.005","article-title":"Synthesis of some steroidal oximes, lactams, thiolactams and their antitumor activities","volume":"72","year":"2007","journal-title":"Steroids"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"413","DOI":"10.2298\/JSC0406413K","article-title":"Photochemical and Beckmann rearrangement of (Z)-cholest-4-en-6-one oxime","volume":"69","author":"Lorenc","year":"2004","journal-title":"J. Serb. Chem. Soc."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"861","DOI":"10.2298\/JSC0411861P","article-title":"Synthesis of 5-azaandrostane-3\u03b2,17\u03b2-diol protected at the 17\u03b2-hydroxyl group","volume":"69","author":"Lorenc","year":"2004","journal-title":"J. Serb. Chem. 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