{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T22:27:15Z","timestamp":1777328835859,"version":"3.51.4"},"reference-count":39,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T00:00:00Z","timestamp":1335744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>A newly found reaction for the synthesis of 3,4-disubstituted 1-hydroxy-pyrrolidine-2,5-diones from 3-substituted coumarins and nitromethane has been elaborated. The reaction involved a simple and convenient experimental procedure. The applicability of the rearrangement reaction is determined.<\/jats:p>","DOI":"10.3390\/molecules17054936","type":"journal-article","created":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T11:06:04Z","timestamp":1335783964000},"page":"4936-4949","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["A New and Efficient Method for the Synthesis of 3,4-Disubstituted Pyrrolidine-2,5-diones"],"prefix":"10.3390","volume":"17","author":[{"given":"Eleonora D.","family":"Ilieva","sequence":"first","affiliation":[{"name":"Sofia University St. Kliment Ohridski, Faculty of Chemistry and Pharmacy, 1, J. Bourchier Blvd., Sofia 1126, Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nevena I.","family":"Petkova","sequence":"additional","affiliation":[{"name":"Sofia University St. Kliment Ohridski, Faculty of Chemistry and Pharmacy, 1, J. 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