{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T14:26:36Z","timestamp":1791123996565,"version":"4.1.0"},"reference-count":67,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2013,10,16]],"date-time":"2013-10-16T00:00:00Z","timestamp":1381881600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Plants have developed general and specific defense mechanisms for protection against various enemies. Among the general defenses, induced resistance has distinct characteristics, such as broad-spectrum resistance and long-lasting effectiveness. This study evaluated over 500 specific chemical compounds derived from native Korean plant species to determine whether they triggered induced resistance against Pectobacterium carotovorum supsp. carotovorum (Pcc) in tobacco (Nicotiana tabacum) and Pseudomonas syringae pv. tomato (Pst) in Arabidopsis thaliana. To select target compound(s) with direct and indirect (volatile) effects, a new Petri-dish-based in vitro disease assay system with four compartments was developed. The screening assay showed that capsaicin, fisetin hydrate, jaceosidin, and farnesiferol A reduced the disease severity significantly in tobacco. Of these four compounds, capsaicin and jaceosidin induced resistance against Pcc and Pst, which depended on both salicylic acid (SA) and jasmonic acid (JA) signaling, using Arabidopsis transgenic and mutant lines, including npr1 and NahG for SA signaling and jar1 for JA signaling. The upregulation of the PR2 and PDF1.2 genes after Pst challenge with capsaicin pre-treatment indicated that SA and JA signaling were primed. These results demonstrate that capsaicin and jaceosidin can be effective triggers of strong induced resistance against both necrotrophic and biotrophic plant pathogens.<\/jats:p>","DOI":"10.3390\/molecules181012877","type":"journal-article","created":{"date-parts":[[2013,10,16]],"date-time":"2013-10-16T12:20:47Z","timestamp":1381926047000},"page":"12877-12895","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Elicitation of Induced Resistance against Pectobacterium carotovorum and Pseudomonas syringae by Specific Individual Compounds Derived from Native Korean Plant Species"],"prefix":"10.3390","volume":"18","author":[{"given":"Geun","family":"Song","sequence":"first","affiliation":[{"name":"Molecular Phytobacteriology Laboratory, Superbacteria Research Center, KRIBB, Daejeon 305-806, Korea"},{"name":"Biosystems and Bioengineering Program, School of Science, University of Science and Technology, Daejeon 305-333, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi","family":"Ryu","sequence":"additional","affiliation":[{"name":"Korea Research Institute of Chemical Technology, P.O. Bos 107, 141 Gajeong-ro, Yuseong, Daejeon 305-600, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Korea Research Institute of Chemical Technology, P.O. Bos 107, 141 Gajeong-ro, Yuseong, Daejeon 305-600, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji","family":"Lee","sequence":"additional","affiliation":[{"name":"Korea Research Institute of Chemical Technology, P.O. Bos 107, 141 Gajeong-ro, Yuseong, Daejeon 305-600, Korea"},{"name":"Graduate School of New Drug Discovery and Development, Chungnam National University, Daejeon 305-764, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung","family":"Choi","sequence":"additional","affiliation":[{"name":"Korea Research Institute of Chemical Technology, P.O. Bos 107, 141 Gajeong-ro, Yuseong, Daejeon 305-600, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choong-Min","family":"Ryu","sequence":"additional","affiliation":[{"name":"Molecular Phytobacteriology Laboratory, Superbacteria Research Center, KRIBB, Daejeon 305-806, Korea"},{"name":"Biosystems and Bioengineering Program, School of Science, University of Science and Technology, Daejeon 305-333, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2013,10,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0074-7696(08)60887-6","article-title":"Systemic acquired resistance in plants","volume":"168","author":"Schneider","year":"1996","journal-title":"Int. Rev. Cytol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/0042-6822(61)90319-1","article-title":"Systemic acquired resistance induced by localized virus infections in plants","volume":"14","author":"Ross","year":"1961","journal-title":"Virology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1080\/07352689609382371","article-title":"Systemic acquired resistance signal transduction","volume":"15","author":"Hunt","year":"1996","journal-title":"Crit. Rev. Plant Sci."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.2307\/3870231","article-title":"Systemic acquired resistance","volume":"8","author":"Ryals","year":"1996","journal-title":"Plant Cell"},{"key":"ref_5","first-page":"432","article-title":"Induced systemic resistance in cucumber in response to 2,6-dichloro-isonicotinic acid and pathogens","volume":"1","author":"Staub","year":"1991","journal-title":"Curr. Plant Sci. Biotechnol. Agric."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1105\/tpc.10.11.1903","article-title":"Impaired fungicide activity in plants blocked in disease resistance signal transduction","volume":"10","author":"Molina","year":"1998","journal-title":"Plant Cell"},{"key":"ref_7","first-page":"645","article-title":"Acquired resistance in Arabidopsis","volume":"4","author":"Uknes","year":"1992","journal-title":"Plant Cell"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1006\/pmpp.1999.0215","article-title":"Induced disease resistance: How do induced plants stop pathogens?","volume":"55","author":"Hammerschmidt","year":"1999","journal-title":"Physiol. Mol. Plant Pathol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.2307\/3869297","article-title":"Coordinate gene activity in response to agents that induce systemic acquired resistance","volume":"3","author":"Ward","year":"1991","journal-title":"Plant Cell"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1104\/pp.112.201913","article-title":"Rhamnolipids elicit defense responses and induce disease resistance against biotrophic, hemibiotrophic, and necrotrophic pathogens that require different signaling pathways in arabidopsis and highlight a central role for salicylic acid","volume":"160","author":"Sanchez","year":"2012","journal-title":"Plant Physiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1094\/MPMI-23-7-0861","article-title":"Involvement of salicylate and jasmonate signaling pathways in arabidopsis interaction with Fusarium graminearum","volume":"23","author":"Makandar","year":"2010","journal-title":"Mol. Plant Microbe Interact."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1094\/PHYTO.2004.94.11.1259","article-title":"Induced systemic resistance and promotion of plant growth by Bacillus spp.","volume":"94","author":"Kloepper","year":"2004","journal-title":"Phytopathology"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1038\/nchembio.164","article-title":"Networking by small-molecule hormones in plant immunity","volume":"5","author":"Pieterse","year":"2009","journal-title":"Nat. Chem. Biol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1146\/annurev.py.08.090170.002155","article-title":"Plant chemotherapy with natural products","volume":"8","author":"Fawcett","year":"1970","journal-title":"Annu. Rev. Phytopathol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1248\/cpb.54.1491","article-title":"Comparative study of chemical constituents of rhubarb from different origins","volume":"54","author":"Komatsu","year":"2006","journal-title":"Chem. Pharm. Bull."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1046\/j.1469-8137.2002.00459.x","article-title":"Emodin\u2014A secondary metabolite with multiple ecological functions in higher plants","volume":"155","author":"Izhaki","year":"2002","journal-title":"New Phytol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"6096","DOI":"10.1021\/jf049379p","article-title":"Anthraquinones isolated from Cassia tora (Leguminosae) seed show an antifungal property against phytopathogenic fungi","volume":"52","author":"Kim","year":"2004","journal-title":"J. Agric. Food Chem."},{"key":"ref_18","first-page":"355","article-title":"On the effect of plant extracts against fireblight (Erwinia amylovora)","volume":"273","author":"Mosch","year":"1989","journal-title":"V Int. Workshop Fireblight ISHS Acta Horticult."},{"key":"ref_19","first-page":"1","article-title":"Extraction, isolation and characterization of bioactive compounds from plants\u2019 extracts","volume":"8","author":"Sasidharan","year":"2011","journal-title":"Afr. J. Tradit. Complement. Altern. Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"3795","DOI":"10.1105\/tpc.112.098343","article-title":"Novel plant immune-priming compounds identified via high-throughput chemical screening target salicylic acid glucosyltransferases in Arabidopsis","volume":"24","author":"Noutoshi","year":"2012","journal-title":"Plant Cell"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1071\/FP04136","article-title":"Plant defence responses: Conservation between models and crops","volume":"32","author":"Anderson","year":"2005","journal-title":"Funct. Plant Biol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"551","DOI":"10.4161\/psb.6.4.14897","article-title":"Interactions of Arabidopsis and M. truncatula with the same Pathogens differ in dependence on ethylene and ethylene response factors","volume":"6","author":"Anderson","year":"2011","journal-title":"Plant Signal.Behav."},{"key":"ref_23","first-page":"e0136","article-title":"Necrotroph attacks on plants: Wanton destruction or covert extortion? The Arabidopsis book","volume":"8","author":"Laluk","year":"2010","journal-title":"Am. Soc. Plant Biol."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Vanneste, J.L. (2000). Fire Blight: The Disease and Its Causative Agent, Erwinia Amylovora, CABI.","DOI":"10.1079\/9780851992945.0000"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1364-3703.2005.00316.x","article-title":"Sclerotinia sclerotiorum (Lib.) de Bary: Biology and molecular traits of a cosmopolitan pathogen","volume":"7","author":"Bolton","year":"2006","journal-title":"Mol. Plant Pathol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"200","DOI":"10.3923\/ajps.2010.200.208","article-title":"Current status of post harvest soft rot in vegetables: A review","volume":"9","author":"Bhat","year":"2010","journal-title":"Asian J. Plant Sci."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1093\/aob\/mci194","article-title":"Recurring challenges from a necrotrophic fungal plant pathogen: A case study with Leptosphaeria maculans (causal agent of blackleg disease inBrassicas) in Western Australia","volume":"96","author":"Sivasithamparam","year":"2005","journal-title":"Ann. Bot."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1104\/pp.111.179531","article-title":"Brachypodium as a model for the grasses: Today and the future","volume":"157","author":"Brkljacic","year":"2011","journal-title":"Plant Physiol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1093\/pcp\/pci122","article-title":"Volatile C6-aldehydes and allo-ocimene activate defense genes and induce resistance against Botrytis cinerea in Arabidopsis thaliana","volume":"46","author":"Kishimoto","year":"2005","journal-title":"Plant Cell Physiol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"4788","DOI":"10.1073\/pnas.081557298","article-title":"Jasmonic acid carboxyl methyltransferase: A key enzyme for jasmonate-regulated plant responses","volume":"98","author":"Seo","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1093\/pcp\/41.4.391","article-title":"Involvement of jasmonate-and salicylate-related signaling pathways for the production of specific herbivore-induced volatiles in plants","volume":"41","author":"Ozawa","year":"2000","journal-title":"Plant Cell Physiol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1046\/j.1365-313x.2002.01198.x","article-title":"Herbivore-induced volatiles induce the emission of ethylene in neighboring lima bean plants","volume":"29","author":"Arimura","year":"2002","journal-title":"Plant J."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"7713","DOI":"10.1073\/pnas.87.19.7713","article-title":"Interplant communication: Airborne methyl jasmonate induces synthesis of proteinase inhibitors in plant leaves","volume":"87","author":"Farmer","year":"1990","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1365-3059.2004.00947.x","article-title":"The salicylic acid-dependent defence pathway is effective against different pathogens in tomato and tobacco","volume":"53","author":"Achuo","year":"2004","journal-title":"Plant Pathol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1105\/tpc.015412","article-title":"ACD6, a novel ankyrin protein, is a regulator and an effector of salicylic acid signaling in the Arabidopsis defense response","volume":"15","author":"Lu","year":"2003","journal-title":"Plant Cell"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1046\/j.1365-313x.1998.00324.x","article-title":"C6-volatiles derived from the lipoxygenase pathway induce a subset of defense-related genes","volume":"16","author":"Bate","year":"2001","journal-title":"Plant J."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1007\/s00442-006-0365-8","article-title":"Priming of plant defense responses in nature by airborne signaling between Artemisia tridentata and Nicotiana attenuata","volume":"148","author":"Kessler","year":"2006","journal-title":"Oecologia"},{"key":"ref_38","unstructured":"Korea Chemical Bank. Available online:http:\/\/www.chembank.org\/."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1093\/jn\/130.9.2243","article-title":"Dietary intakes of flavonols, flavones and isoflavones by japanese women and the inverse correlation between quercetin intake and plasma LDL cholesterol concentration","volume":"130","author":"Arai","year":"2000","journal-title":"J. Nutr."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"3164","DOI":"10.1167\/iovs.04-1369","article-title":"Flavonoids protect human retinal pigment epithelial cells from oxidative-stress\u2013induced death","volume":"47","author":"Hanneken","year":"2006","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1067\/mai.2003.1456","article-title":"Fisetin, a flavonol, inhibits TH2-type cytokine production by activated human basophils","volume":"111","author":"Higa","year":"2003","journal-title":"J. Allergy Clin. Immunol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s00204-002-0346-6","article-title":"Wogonin and fisetin induction of apoptosis through activation of easpase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1","volume":"76","author":"Chen","year":"2002","journal-title":"Arch. Toxicol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1093\/carcin\/bgn078","article-title":"Fisetin, a novel dietary flavonoid, causes Apoptosis and cell cycle arrest in human prostate cancer LNCaP cells","volume":"29","author":"Khan","year":"2008","journal-title":"Carcinogenesis"},{"key":"ref_44","first-page":"561","article-title":"Advances in studies of species, habitats distribution and chemical composition of Snow lotuses (Saussurea) in China","volume":"16","author":"Chen","year":"1999","journal-title":"Chin. Bull. Bot."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.jep.2005.01.054","article-title":"Inhibitory effect of jaceosidin isolated from Artemisiaargyi on the function of E6 and E7 oncoproteins of HPV 16","volume":"98","author":"Lee","year":"2005","journal-title":"J. Ethnopharmacol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1021\/np900158f","article-title":"Influenza A (H1N1) antiviral and cytotoxic agents from Ferula assa-foetida","volume":"72","author":"Lee","year":"2009","journal-title":"J. Nat. Prod."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Veloso, J., Prego, C., Varela, M., Carballeira, R., Bernal, A., Merino, F., and D\u00edaz, J. (2013). Properties of capsaicinoids for the control of fungi and oomycetes pathogenic to pepper. Plant Biol.","DOI":"10.1111\/j.1438-8677.2012.00717.x"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1128\/jb.50.4.459-467.1945","article-title":"The paper-disc agar-plate method for the assay of antibiotic substances","volume":"50","author":"Sherwood","year":"1945","journal-title":"J. Bacteriol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1002\/ps.1714","article-title":"Jasmonate-and salicylate-mediated plant defense responses to insect herbivores, pathogens and parasitic plants","volume":"65","author":"Smith","year":"2009","journal-title":"Pest Manag. Sci."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"8711","DOI":"10.1073\/pnas.130425197","article-title":"Enhancement of induced disease resistance by simultaneous activation of salicylate-and jasmonate-dependent defense pathways in Arabidopsis thaliana","volume":"97","author":"Pieterse","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"18842","DOI":"10.1073\/pnas.0708139104","article-title":"Regulation of tradeoffs between plant defenses against pathogens with different lifestyles","volume":"104","author":"Spoel","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1469-8137.2004.01211.x","article-title":"Evaluation of natural and synthetic stimulants of plant immunity by microarray technology","volume":"165","author":"Mueller","year":"2005","journal-title":"New Phytol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S1369-5266(02)00275-3","article-title":"Cross talk between signaling pathways in pathogen defense","volume":"5","author":"Kunkel","year":"2002","journal-title":"Curr. Opin. Plant Biol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"e1000772","DOI":"10.1371\/journal.pgen.1000772","article-title":"Network properties of robust immunity in plants","volume":"5","author":"Tsuda","year":"2009","journal-title":"PLoS Genet."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1146\/annurev-phyto-081211-172955","article-title":"Plant Immunity to necrotrophs","volume":"50","author":"Mengiste","year":"2012","journal-title":"Annu. Rev. Phytopathol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"252","DOI":"10.3389\/fpls.2013.00252","article-title":"Reprogramming of plants during systemic acquired resistance","volume":"4","author":"Gruner","year":"2013","journal-title":"Front. Plant Sci."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0378-8741(96)01384-0","article-title":"The antimicrobial properties of chile peppers (Capsicum species) and their uses in mayan medicine","volume":"52","author":"Cichewicz","year":"1996","journal-title":"J. Ethnopharmacol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0378-8741(98)00134-2","article-title":"Antimicrobial properties of alkamides present in flavouring plants traditionally used in Mesoamerica: Affinin and capsaicin","volume":"64","year":"1999","journal-title":"J. Ethnopharmacol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1271\/bbb.66.532","article-title":"Studies on the antimicrobial mechanisms of capsaicin using yeast DNA microarray","volume":"66","author":"Kurita","year":"2002","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1002\/app.23766","article-title":"Study on the antimicrobial activities of the capsaicin microcapsules","volume":"102","author":"Xing","year":"2006","journal-title":"J. Appl. Polym. Sci."},{"key":"ref_61","first-page":"417","article-title":"Effect of capsaicin on germination of Colletotrichum capsici conidia","volume":"42","author":"Kraikruan","year":"2008","journal-title":"Kasetsart J. Nat. Sci."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1104\/pp.88.3.936","article-title":"Antifungal hydrolases in pea tissue","volume":"88","author":"Mauch","year":"1988","journal-title":"Plant Physiol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.pmpp.2003.09.002","article-title":"Induced defence in tobacco by Pseudomonas chlororaphis strain O6 involves at least the ethylene pathway","volume":"63","author":"Spencer","year":"2003","journal-title":"Physiol. Mol. Plant Pathol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"e48744","DOI":"10.1371\/journal.pone.0048744","article-title":"Induced resistance by a long-chain bacterial volatile: Elicitation of plant systemic defense by a C13 volatile produced by Paenibacillus polymyxa","volume":"7","author":"Lee","year":"2012","journal-title":"PLoS One"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.pestbp.2012.04.007","article-title":"Plumbagin as a new natural herbicide candidate for Sicyon angulatus control agent with the target 8-amino-7-oxononanoate synthase","volume":"103","author":"Choi","year":"2012","journal-title":"Pestic. Biochem. Physiol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/0031-9422(86)88047-5","article-title":"Epi-isoshinanolone from Plumbago scandens","volume":"25","author":"Bhattacharyya","year":"1986","journal-title":"Phytochemistry"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"350","DOI":"10.5423\/PPJ.NT.02.2013.0018","article-title":"Systemic induction of the small antibacterial compound in the leaf exudate during benzothiadiazole-elicited systemic acquired resistance in pepper","volume":"29","author":"Lee","year":"2013","journal-title":"Plant Pathol. 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