{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T04:04:58Z","timestamp":1793160298834,"version":"4.5.0"},"reference-count":203,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2016,2,9]],"date-time":"2016-02-09T00:00:00Z","timestamp":1454976000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Sectorial Operational Programme Human Resources Development (SOP HRD)","award":["SOP HRD\/159\/1.5\/S\/135760"],"award-info":[{"award-number":["SOP HRD\/159\/1.5\/S\/135760"]}]},{"name":"University of Medicine and Pharmacy Carol Davila, Bucharest, Romania","award":["Young Scientist Grant 2014-2016"],"award-info":[{"award-number":["Young Scientist Grant 2014-2016"]}]},{"name":"Romanian National Authority for Scientific Research andInnovation, CNCS \u2013 UEFISCDI","award":["PN-II-RU-TE-2014-4-1879"],"award-info":[{"award-number":["PN-II-RU-TE-2014-4-1879"]}]},{"name":"Romanian-US Fulbright Commission","award":["Senior Fulbright Grant 2015-2016"],"award-info":[{"award-number":["Senior Fulbright Grant 2015-2016"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>There is a growing interest in the development of organic nanomaterials for biomedical applications. An increasing number of studies focus on the uses of nanomaterials with organic structure for regeneration of bone, cartilage, skin or dental tissues. Solid evidence has been found for several advantages of using natural or synthetic organic nanostructures in a wide variety of dental fields, from implantology, endodontics, and periodontics, to regenerative dentistry and wound healing. Most of the research is concentrated on nanoforms of chitosan, silk fibroin, synthetic polymers or their combinations, but new nanocomposites are constantly being developed. The present work reviews in detail current research on organic nanoparticles and their potential applications in the dental field.<\/jats:p>","DOI":"10.3390\/molecules21020207","type":"journal-article","created":{"date-parts":[[2016,2,10]],"date-time":"2016-02-10T01:43:44Z","timestamp":1455068624000},"page":"207","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":99,"title":["Organic Nanomaterials and Their Applications in the Treatment of Oral Diseases"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7719-3988","authenticated-orcid":false,"given":"Maria","family":"Virlan","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Faculty of Dentistry, University of Medicine and Pharmacy Carol Davila, Blvd. EroiiSanitari, No. 8, RO-050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Miricescu","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Dentistry, University of Medicine and Pharmacy Carol Davila, Blvd. EroiiSanitari, No. 8, RO-050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radu","family":"Radulescu","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Dentistry, University of Medicine and Pharmacy Carol Davila, Blvd. EroiiSanitari, No. 8, RO-050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Sabliov","sequence":"additional","affiliation":[{"name":"Agricultural and Biological Engineering Department, Louisiana State University and LSU Ag Center, 149 EB Doran Building, Baton Rouge, LA 70803, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Totan","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Dentistry, University of Medicine and Pharmacy Carol Davila, Blvd. EroiiSanitari, No. 8, RO-050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogdan","family":"Calenic","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Dentistry, University of Medicine and Pharmacy Carol Davila, Blvd. EroiiSanitari, No. 8, RO-050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Greabu","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Dentistry, University of Medicine and Pharmacy Carol Davila, Blvd. EroiiSanitari, No. 8, RO-050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2016,2,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"930","DOI":"10.3390\/vaccines3040930","article-title":"From antigen delivery system to adjuvanticy: The board application of nanoparticles in vaccinology","volume":"3","author":"Boraschi","year":"2015","journal-title":"Vaccines"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.addr.2012.09.033","article-title":"Nanoparticle and targeted systems for cancer therapy","volume":"64","author":"Blanchette","year":"2012","journal-title":"Adv. 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