{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T07:50:42Z","timestamp":1791877842937,"version":"4.3.4"},"reference-count":155,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2016,7,29]],"date-time":"2016-07-29T00:00:00Z","timestamp":1469750400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Phenylethanoid glycosides (PhGs) are widely distributed in traditional Chinese medicines as well as in other medicinal plants, and they were characterized by a phenethyl alcohol (C6-C2) moiety attached to a \u03b2-glucopyranose\/\u03b2-allopyranose via a glycosidic bond. The outstanding activity of PhGs in diverse diseases proves their importance in medicinal chemistry research. This review summarizes new findings on PhGs over the past 10 years, concerning the new structures, their bioactivities, including neuroprotective, anti-inflammatory, antioxidant, antibacterial and antivirus, cytotoxic, immunomodulatory, and enzyme inhibitory effects, and pharmacokinetic properties.<\/jats:p>","DOI":"10.3390\/molecules21080991","type":"journal-article","created":{"date-parts":[[2016,7,29]],"date-time":"2016-07-29T10:40:24Z","timestamp":1469788824000},"page":"991","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":144,"title":["Phenylethanoid Glycosides: Research Advances in Their Phytochemistry, Pharmacological Activity and Pharmacokinetics"],"prefix":"10.3390","volume":"21","author":[{"given":"Zhenzhen","family":"Xue","sequence":"first","affiliation":[{"name":"Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2016,7,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.foodchem.2011.02.083","article-title":"Antioxidant and cholinesterases inhibitory activities of Verbascum xanthophoeniceum Griseb and its phenylethanoid glycosides","volume":"128","author":"Georgiev","year":"2011","journal-title":"Food Chem."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.fitote.2011.10.003","article-title":"Iridoid, phenylethanoid and flavonoid glycosides from Sideritis trojana","volume":"83","author":"Kirmizibekmez","year":"2012","journal-title":"Fitoterapia"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1039\/NP9941100591","article-title":"Phenylethanoid glycosides in plants: Structure and biological activity","volume":"11","author":"Jimenez","year":"1994","journal-title":"Nat. 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