{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:09:41Z","timestamp":1790338181142,"version":"4.1.0"},"reference-count":25,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2017,1,6]],"date-time":"2017-01-06T00:00:00Z","timestamp":1483660800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>The follow-up of phytochemical and pharmacological studies of Sida rhombifolia L. (Malvaceae) aims to strengthen the chemosystematics and pharmacology of Sida genera and support the ethnopharmacological use of this species as hypotensive herb. The present work reports phytoconstituents isolated and identified from aerial parts of S. rhombifolia by using chromatographic and spectroscopic methods. The study led to the isolation of scopoletin (1), scoporone (2), ethoxy-ferulate (3), kaempferol (4), kaempferol-3-O-\u03b2-d-glycosyl-6\u2032\u2032-\u03b1-d-rhamnose (5), quindolinone (6), 11-methoxy-quindoline (7), quindoline (8), and the cryptolepine salt (9). The alkaloids quindolinone (6) and cryptolepine salt (9) showed vasorelaxant activity in rodent isolated mesenteric arteries.<\/jats:p>","DOI":"10.3390\/molecules22010094","type":"journal-article","created":{"date-parts":[[2017,1,6]],"date-time":"2017-01-06T10:08:12Z","timestamp":1483697292000},"page":"94","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Alkaloids and Phenolic Compounds from Sida rhombifolia L. (Malvaceae) and Vasorelaxant Activity of Two Indoquinoline Alkaloids"],"prefix":"10.3390","volume":"22","author":[{"given":"Otemberg","family":"Chaves","sequence":"first","affiliation":[{"name":"Post Graduation Program in Bioactive Natural and Synthetic Products, Health Sciences Center, Federal University of Para\u00edba, 58051-970 Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanna","family":"Teles","sequence":"additional","affiliation":[{"name":"Post Graduation in Development and Technological Innovation in Medicines, Federal University of Paraiba, 58051-900 Jo\u00e3o Pessoa, PB, Brazil"},{"name":"Department of Chemistry and Physics, Agrarian Sciences Center, Federal University of Para\u00edba, 58397-972 Areia, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7199-8053","authenticated-orcid":false,"given":"Matheus","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Post Graduation Program in Bioactive Natural and Synthetic Products, Health Sciences Center, Federal University of Para\u00edba, 58051-970 Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le\u00f4nidas","family":"Mendes Junior","sequence":"additional","affiliation":[{"name":"Post Graduation Program in Bioactive Natural and Synthetic Products, Health Sciences Center, Federal University of Para\u00edba, 58051-970 Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Agra","sequence":"additional","affiliation":[{"name":"Post Graduation Program in Bioactive Natural and Synthetic Products, Health Sciences Center, Federal University of Para\u00edba, 58051-970 Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valdir","family":"Braga","sequence":"additional","affiliation":[{"name":"Post Graduation Program in Bioactive Natural and Synthetic Products, Health Sciences Center, Federal University of Para\u00edba, 58051-970 Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00e2nia","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Molecular Sciences, Federal Rural University of Pernambuco, Campus Dois Irm\u00e3os, 52171-900 Recife, PE, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Souza","sequence":"additional","affiliation":[{"name":"Post Graduation Program in Bioactive Natural and Synthetic Products, Health Sciences Center, Federal University of Para\u00edba, 58051-970 Jo\u00e3o Pessoa, PB, Brazil"},{"name":"Post Graduation in Development and Technological Innovation in Medicines, Federal University of Paraiba, 58051-900 Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2017,1,6]]},"reference":[{"key":"ref_1","unstructured":"Carvalho, P.E.R., and Gaiad, S. \u00c1rvore do Conhecimento Esp\u00e9cies Arb\u00f3reas Brasileiras. 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