{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T14:39:40Z","timestamp":1771166380944,"version":"3.50.1"},"reference-count":70,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2017,9,4]],"date-time":"2017-09-04T00:00:00Z","timestamp":1504483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Bovine mastitis a major disease that is commonly associated with bacterial infection. The common treatment is with antibiotics administered intramammary into infected quarters of the udder. The excessive use of antibiotics leads to multidrug resistance and associated risks for human health. In this context, the search for alternative drugs based on plants has become a priority in livestock medicine. These products have a low manufacturing cost and no reports of antimicrobial resistance to these have been documented. In this context, the main objective of this study was to determine the antimicrobial effect of extracts and products of several indigenous, or acclimatized plants on pathogens isolated from bovine mastitis. A total of eleven plant alcoholic extracts and eight plant-derived products were tested against 32 microorganisms isolated from milk. The obtained results have shown an inhibition of bacterial growth for all tested plants, with better results for Evernia prunastri, Artemisia absinthium, and Lavandula angustifolia. Moreover, E. prunastri, Populus nigra, and L. angustifolia presented small averages of minimum inhibitory and bactericidal concentrations. Among the plant-derived products, three out of eight have shown a strong anti-microbial effect comparable with the effect of florfenicol and enrofloxacin, and better than individual plant extracts possibly due to synergism. These results suggest an important anti-microbial effect of these products on pathogens isolated from bovine mastitis with a possible applicability in this disease.<\/jats:p>","DOI":"10.3390\/molecules22091473","type":"journal-article","created":{"date-parts":[[2017,9,4]],"date-time":"2017-09-04T11:11:52Z","timestamp":1504523512000},"page":"1473","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Medicinal Plants Based Products Tested on Pathogens Isolated from Mastitis Milk"],"prefix":"10.3390","volume":"22","author":[{"given":"Claudia","family":"Pa\u0219ca","sequence":"first","affiliation":[{"name":"Department of Apiculture and Sericiculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca 400372, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liviu","family":"M\u0103rghita\u0219","sequence":"additional","affiliation":[{"name":"Department of Apiculture and Sericiculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca 400372, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Dezmirean","sequence":"additional","affiliation":[{"name":"Department of Apiculture and Sericiculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca 400372, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8079-4354","authenticated-orcid":false,"given":"Otilia","family":"Bobi\u0219","sequence":"additional","affiliation":[{"name":"Life Science Institute \u201cKing Michael I of Romania\u201d, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca 400372, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victori\u021ba","family":"Bonta","sequence":"additional","affiliation":[{"name":"Life Science Institute \u201cKing Michael I of Romania\u201d, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca 400372, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flore","family":"Chiril\u0103","sequence":"additional","affiliation":[{"name":"Department of Microbiology (Veterinary Medicine), University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca 400372, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioana","family":"Matei","sequence":"additional","affiliation":[{"name":"Department of Microbiology (Veterinary Medicine), University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca 400372, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicodim","family":"Fi\u021b","sequence":"additional","affiliation":[{"name":"Department of Microbiology (Veterinary Medicine), University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca 400372, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2017,9,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1053\/tvjl.2002.0724","article-title":"Bovine mastitis: An evolving disease","volume":"164","author":"Bradley","year":"2002","journal-title":"Vet. 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