{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:59:27Z","timestamp":1791921567554,"version":"4.3.4"},"reference-count":126,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2018,10,9]],"date-time":"2018-10-09T00:00:00Z","timestamp":1539043200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Significant attention has been given to organotin(IV) dithiocabamate compounds in recent times. This is due to their ability to stabilize specific stereochemistry in their complexes, and their diverse application in agriculture, biology, catalysis and as single source precursors for tin sulfide nanoparticles. These complexes have good coordination chemistry, stability and diverse molecular structures which, thus, prompt their wide range of biological activities. Their unique stereo-electronic properties underline their relevance in the area of medicinal chemistry. Organotin(IV) dithiocabamate compounds owe their functionalities and usefulness to the individual properties of the organotin(IV) and the dithiocarbamate moieties present within the molecule. These individual properties create a synergy of action in the hybrid complex, prompting an enhanced biological activity. In this review, we discuss the chemistry of organotin(IV) dithiocarbamate complexes that accounts for their relevance in biology and medicine.<\/jats:p>","DOI":"10.3390\/molecules23102571","type":"journal-article","created":{"date-parts":[[2018,10,9]],"date-time":"2018-10-09T11:10:44Z","timestamp":1539083444000},"page":"2571","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":149,"title":["Organotin(IV) Dithiocarbamate Complexes: Chemistry and Biological Activity"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7769-5264","authenticated-orcid":false,"given":"Jerry O.","family":"Adeyemi","sequence":"first","affiliation":[{"name":"Material Science Innovation and Modelling (MaSIM) Research Focus Area, Faculty of Natural and Agricultural Science, North-West University, Mafikeng Campus, Private Bag X2046, Mmabatho 2735, South Africa"},{"name":"Department of Chemistry, Faculty of Natural and Agricultural Science, North-West University, Mafikeng Campus, Private Bag X2046, Mmabatho 2735, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damian C.","family":"Onwudiwe","sequence":"additional","affiliation":[{"name":"Material Science Innovation and Modelling (MaSIM) Research Focus Area, Faculty of Natural and Agricultural Science, North-West University, Mafikeng Campus, Private Bag X2046, Mmabatho 2735, South Africa"},{"name":"Department of Chemistry, Faculty of Natural and Agricultural Science, North-West University, Mafikeng Campus, Private Bag X2046, Mmabatho 2735, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,10,9]]},"reference":[{"key":"ref_1","first-page":"5","article-title":"The scope of metal complexes in drug design\u2014A review","volume":"49","author":"Pattan","year":"2012","journal-title":"Indian Drugs"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1029039","DOI":"10.1080\/23312009.2015.1029039","article-title":"Antituberculosis study of organotin(IV) complexes: A review","volume":"1","author":"Iqbal","year":"2015","journal-title":"Cogent Chem."},{"key":"ref_3","unstructured":"Miller, J.S., and Drillon, M. 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