{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T07:14:05Z","timestamp":1780557245928,"version":"3.54.1"},"reference-count":34,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T00:00:00Z","timestamp":1559260800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Hungarian Research Development and Innovation Office","award":["FK123961"],"award-info":[{"award-number":["FK123961"]}]},{"name":"J\u00e1nos Bolyai Research Scholarship of the Hungarian Academy of Sciences","award":["BO\/00278\/17\/7"],"award-info":[{"award-number":["BO\/00278\/17\/7"]}]},{"name":"New National Excellence Program of the Ministry of Human Capacities","award":["\u00daNKP-18-4-BME-131"],"award-info":[{"award-number":["\u00daNKP-18-4-BME-131"]}]},{"name":"New National Excellence Program of the Ministry of Human Capacities","award":["\u00daNKP-18-3-I-BME-119"],"award-info":[{"award-number":["\u00daNKP-18-3-I-BME-119"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>An efficient and practical method was developed for the synthesis of new (1,2,3\u2011triazol\u20114\u2011yl)methyl phosphinates and (1,2,3-triazol-4-yl)methyl phosphates by the copper(I)\u2011catalyzed azide-alkyne cycloaddition (CuAAC) of organic azides and prop-2-ynyl phosphinate or prop-2-ynyl phosphate. The synthesis of (1\u2011benzyl-1H-1,2,3-triazol-4-yl)methyl diphenylphosphinate was optimized with respect to the reaction parameters, such as the temperature, reaction time, and catalyst loading. The approach was applied to a range of organic azides, which confirmed the wide scope and the substituent tolerance of the process. The method elaborated represents a novel approach for the synthesis of the target compounds.<\/jats:p>","DOI":"10.3390\/molecules24112085","type":"journal-article","created":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T11:59:56Z","timestamp":1559303996000},"page":"2085","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Synthesis of (1,2,3-triazol-4-yl)methyl Phosphinates and (1,2,3-Triazol-4-yl)methyl Phosphates by Copper-Catalyzed Azide-Alkyne Cycloaddition"],"prefix":"10.3390","volume":"24","author":[{"given":"Anna","family":"Tripolszky","sequence":"first","affiliation":[{"name":"Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krisztina","family":"N\u00e9meth","sequence":"additional","affiliation":[{"name":"MS Metabolomics Laboratory, Instrumentation Center, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar Tud\u00f3sok Krt. 2., H-1117 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e1l Tam\u00e1s","family":"Szab\u00f3","sequence":"additional","affiliation":[{"name":"MS Metabolomics Laboratory, Instrumentation Center, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar Tud\u00f3sok Krt. 2., H-1117 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5107-7089","authenticated-orcid":false,"given":"Erika","family":"B\u00e1lint","sequence":"additional","affiliation":[{"name":"Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,5,31]]},"reference":[{"key":"ref_1","unstructured":"Katritzky, A.R., Rees, C.W., and Scriven, C.W.V. 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