{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T20:41:42Z","timestamp":1788381702258,"version":"build-2803163510"},"reference-count":46,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2019,6,8]],"date-time":"2019-06-08T00:00:00Z","timestamp":1559952000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>We report on new Zn\u2013Salen oligomer receptors able to recognize a nerve agent simulant, namely dimethyl methylphosphonate (DMMP), by a supramolecular approach. In particular, three Zn-Salen oligomers (Zn\u2013Oligo\u2013A, \u2013B, and \u2013C), differing by the length distribution, were obtained and characterized by NMR, Gel Permeation Chromatography (GPC), UV-Vis, and fluorescence spectroscopy. Furthermore, we investigated their recognition properties towards DMMP by using fluorescence measurements. We found that the recognition ability depends on the length of the oligomeric chain, and the Zn\u2013Oligo\u2013C shows a binding constant value higher than those already reported in literature for the DMMP detection.<\/jats:p>","DOI":"10.3390\/molecules24112160","type":"journal-article","created":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T03:16:51Z","timestamp":1560136611000},"page":"2160","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Supramolecular Detection of a Nerve Agent Simulant by Fluorescent Zn\u2013Salen Oligomer Receptors"],"prefix":"10.3390","volume":"24","author":[{"given":"Roberta","family":"Puglisi","sequence":"first","affiliation":[{"name":"Department of Chemical Sciences, University of Catania, Viale A. Doria 6, 95100 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3382-9272","authenticated-orcid":false,"given":"Placido G.","family":"Mineo","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, University of Catania, Viale A. Doria 6, 95100 Catania, Italy"},{"name":"CNR-IPCB Istituto per i Polimeri, Compositi e Biomateriali, Via P. Gaifami 18, I-95126 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Pappalardo","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, University of Catania, Viale A. Doria 6, 95100 Catania, Italy"},{"name":"Department of Chemical Sciences, University of Catania Research Unit (I.N.S.T.M.) UdR of Catania, Viale A. Doria 6, 95125 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6850-3080","authenticated-orcid":false,"given":"Antonino","family":"Gulino","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, University of Catania, Viale A. Doria 6, 95100 Catania, Italy"},{"name":"Department of Chemical Sciences, University of Catania Research Unit (I.N.S.T.M.) UdR of Catania, Viale A. Doria 6, 95125 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1584-5869","authenticated-orcid":false,"given":"Giuseppe","family":"Trusso Sfrazzetto","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, University of Catania, Viale A. Doria 6, 95100 Catania, Italy"},{"name":"Department of Chemical Sciences, University of Catania Research Unit (I.N.S.T.M.) UdR of Catania, Viale A. Doria 6, 95125 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,6,8]]},"reference":[{"key":"ref_1","unstructured":"Romano, J.A., Lukey, B.J., and Salem, H. (2007). Chemical Warfare Agents Chemistry, Pharmacology, Toxicology, and Therapeutics, Taylor & Francis Group. [2nd ed.]."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1021\/ar2002864","article-title":"Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents","volume":"45","author":"Mercey","year":"2012","journal-title":"Acc. Chem. Res."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1080\/15563650.2018.1469759","article-title":"Novichok: A murderous nerve agent attack in the UK","volume":"56","author":"Vale","year":"2018","journal-title":"Clin. 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