{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T15:02:41Z","timestamp":1761490961259,"version":"build-2065373602"},"reference-count":40,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,2,23]],"date-time":"2020-02-23T00:00:00Z","timestamp":1582416000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["CTQ2011-26481, CTQ2015-69583-R and RTI2018-094605-B-I00"],"award-info":[{"award-number":["CTQ2011-26481, CTQ2015-69583-R and RTI2018-094605-B-I00"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>A family of complexes of the formula trans-[RuCl2(L)(R-pybox)] (R-pybox = (S,S)-iPr-pybox, (R,R)-Ph-pybox, L = monodentate phosphonite, PPh(OR)2, and phosphinite, L = PPh2(OR), ligands) were screened in the catalytic asymmetric transfer hydrogenation of acetophenone, observing a strong influence of the nature of both the R-pybox substituents and the L ligand in the process. The best results were obtained with complex trans-[RuCl2{PPh2(OEt)}{(R,R)-Ph-pybox}] (2c), which provided high conversion and enantioselectivity (up to 96% enantiomeric excess, e.e.) for the reduction of a variety of aromatic ketones, affording the (S)-benzylalcohols.<\/jats:p>","DOI":"10.3390\/molecules25040990","type":"journal-article","created":{"date-parts":[[2020,2,27]],"date-time":"2020-02-27T03:21:16Z","timestamp":1582773676000},"page":"990","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Asymmetric Transfer Hydrogenation of Arylketones Catalyzed by Enantiopure Ruthenium(II)\/Pybox Complexes Containing Achiral Phosphonite and Phosphinite Ligands"],"prefix":"10.3390","volume":"25","author":[{"given":"Miguel","family":"Claros","sequence":"first","affiliation":[{"name":"Departamento de Qu\u00edmica Org\u00e1nica e Inorg\u00e1nica-IUQOEM (Unidad Asociada al CSIC), Centro de Innovaci\u00f3n en Qu\u00edmica Avanzada (ORFEO-CINQA), Universidad de Oviedo, E-33006 Oviedo, Principado de Asturias, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eire","family":"de Juli\u00e1n","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica Org\u00e1nica e Inorg\u00e1nica-IUQOEM (Unidad Asociada al CSIC), Centro de Innovaci\u00f3n en Qu\u00edmica Avanzada (ORFEO-CINQA), Universidad de Oviedo, E-33006 Oviedo, Principado de Asturias, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josefina","family":"D\u00edez","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica Org\u00e1nica e Inorg\u00e1nica-IUQOEM (Unidad Asociada al CSIC), Centro de Innovaci\u00f3n en Qu\u00edmica Avanzada (ORFEO-CINQA), Universidad de Oviedo, E-33006 Oviedo, Principado de Asturias, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Lastra","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica Org\u00e1nica e Inorg\u00e1nica-IUQOEM (Unidad Asociada al CSIC), Centro de Innovaci\u00f3n en Qu\u00edmica Avanzada (ORFEO-CINQA), Universidad de Oviedo, E-33006 Oviedo, Principado de Asturias, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9921-0029","authenticated-orcid":false,"given":"M. Pilar","family":"Gamasa","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica Org\u00e1nica e Inorg\u00e1nica-IUQOEM (Unidad Asociada al CSIC), Centro de Innovaci\u00f3n en Qu\u00edmica Avanzada (ORFEO-CINQA), Universidad de Oviedo, E-33006 Oviedo, Principado de Asturias, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,2,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4608","DOI":"10.1021\/acs.organomet.8b00625","article-title":"Asymmetric Transfer Hydrogenation of Ketones with Well-Defined Manganese(I) PNN and PNNP Complexes","volume":"37","author":"Demmans","year":"2018","journal-title":"Organometallics"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1021\/ar5003818","article-title":"Recent Advances in Osmium-Catalyzed Hydrogenation and Dehydrogenation Reactions","volume":"48","author":"Chelucci","year":"2015","journal-title":"Acc. 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