{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T08:15:13Z","timestamp":1780388113680,"version":"3.54.1"},"reference-count":63,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T00:00:00Z","timestamp":1593734400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002848","name":"Comisi\u00f3n Nacional de Investigaci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"publisher","award":["1180059"],"award-info":[{"award-number":["1180059"]}],"id":[{"id":"10.13039\/501100002848","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Persicaria maculosa (Polygonaceae) (known as lady\u2019s thumb) is an annual morphologically variable weed that is widely distributed in Chile. The purpose of this study was to investigate the antifeedant potential of methanolic (MeOH), ethanolic (EtOH), and dichloromethane (DCM) extracts from the aerial parts of this plant collected in the Valpara\u00edso and Curic\u00f3 provinces (Chile) and relate this activity to the antioxidant capacity and the presence of phenolic compounds in the extracts. A phenolic profile based on HPLC-ESI-MS\/MS allowed the identification of 26 phenolic compounds, most of them glycosyl derivatives of isorhamnetin, quercetin, and kaempferol. In addition, the total phenolic content (TP), total flavonoids (TF), and antioxidant activity measured by 2,2-diphenyl-1-picrylhydrazyl (DPPH), superoxide anion scavenging (O2\u2212), ferric-reducing antioxidant power (FRAP), and cupric-reducing antioxidant capacity (CUPRAC) of the extracts are reported. The antifeedant potentials of the plant extracts were tested against Epilachna paenulata, Pseudaletia adultera, Macrosiphum euphorbiae, and Diaphorina citri insects for the first time. The activity against the aphid M. euphorbiae was significant for the DCM extracts of plants from Valpara\u00edso and Curic\u00f3 (settling % = 23% \u00b1 4% and 23% \u00b1 5%, respectively). The antifeedant activities against the beetle E. paenulata and the lepidoptera P. adultera were significant for Valpara\u00edso extracts, especially when tested against E. Paenulata (IFP = 1.0 \u00b1 0.0). Finally, the MeOH and EtOH extracts from Valpara\u00edso plants reduced the diet consumption of the psilid D. citri (p &lt; 0.05). The results showed that P. maculosa is a good source of flavonoids with some antioxidant capacities and has potential interest as botanical eco-friendly alternative with deterrent activity.<\/jats:p>","DOI":"10.3390\/molecules25133054","type":"journal-article","created":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T11:07:42Z","timestamp":1594033662000},"page":"3054","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Phenolic Fingerprinting, Antioxidant, and Deterrent Potentials of Persicaria maculosa Extracts"],"prefix":"10.3390","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7607-4853","authenticated-orcid":false,"given":"Luisa","family":"Quesada-Romero","sequence":"first","affiliation":[{"name":"Laboratorio de Ecolog\u00eda Qu\u00edmica, Instituto de Qu\u00edmica, Pontificia Universidad Cat\u00f3lica de Valpara\u00edso, Avda. Universidad 330. Curauma, Valpara\u00edso 2340000, Chile"},{"name":"Facultad de Ciencias para el cuidado de la Salud, Universidad San Sebasti\u00e1n, General Lagos 1163, Valdivia 5090000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Fern\u00e1ndez-Galleguillos","sequence":"additional","affiliation":[{"name":"Instituto de Farmacia, Facultad de Ciencias, Universidad Austral de Chile, Valdivia 5090000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3566-1979","authenticated-orcid":false,"given":"Jan","family":"Bergmann","sequence":"additional","affiliation":[{"name":"Laboratorio de Ecolog\u00eda Qu\u00edmica, Instituto de Qu\u00edmica, Pontificia Universidad Cat\u00f3lica de Valpara\u00edso, Avda. Universidad 330. Curauma, Valpara\u00edso 2340000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda-Eugenia","family":"Amor\u00f3s","sequence":"additional","affiliation":[{"name":"Laboratorio de Ecolog\u00eda Qu\u00edmica, Facultad de Qu\u00edmica, Universidad de la Rep\u00fablica, Gral. Flores 2124 CP 11800, Montevideo 11800, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7285-7033","authenticated-orcid":false,"given":"Felipe","family":"Jim\u00e9nez-Aspee","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias B\u00e1sicas Biom\u00e9dicas, Facultad de Ciencias de la Salud, Universidad de Talca, Avenida Lircay S\/N, Talca 3460000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2527-2400","authenticated-orcid":false,"given":"Andr\u00e9s","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Laboratorio de Ecolog\u00eda Qu\u00edmica, Facultad de Qu\u00edmica, Universidad de la Rep\u00fablica, Gral. Flores 2124 CP 11800, Montevideo 11800, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4552-3123","authenticated-orcid":false,"given":"Mario","family":"Simirgiotis","sequence":"additional","affiliation":[{"name":"Instituto de Farmacia, Facultad de Ciencias, Universidad Austral de Chile, Valdivia 5090000, Chile"},{"name":"Center for Interdisciplinary Studies on the Nervous System, Universidad Austral de Chile, Campus Isla Teja, Valdivia 5090000, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Rossini","sequence":"additional","affiliation":[{"name":"Laboratorio de Ecolog\u00eda Qu\u00edmica, Facultad de Qu\u00edmica, Universidad de la Rep\u00fablica, Gral. Flores 2124 CP 11800, Montevideo 11800, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,7,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s40816-016-0016-5","article-title":"A preliminary evaluation of cytotoxicity, antihyperglycemic and antinociceptive activity of Polygonum hydropiper L. ethanolic leaf extract","volume":"2","author":"Oany","year":"2017","journal-title":"Clin. Phytoscience"},{"key":"ref_2","first-page":"21","article-title":"The genus Polygonum (Polygonaceae): An ethnopharmacological and phytochemical perspectives - Review","volume":"6","author":"Narasimhulu","year":"2014","journal-title":"Int. J. Pharm. Pharm. 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