{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T05:57:18Z","timestamp":1790488638816,"version":"4.1.0"},"reference-count":29,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T00:00:00Z","timestamp":1594598400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010751","name":"Fondecyt","doi-asserted-by":"publisher","award":["1180265, 1191902"],"award-info":[{"award-number":["1180265, 1191902"]}],"id":[{"id":"10.13039\/501100010751","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fondequip","award":["EQM150106"],"award-info":[{"award-number":["EQM150106"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>A new copper (I) complex, [Cu(NN1)2](ClO4), was synthesized, where NN1 was a imine ligand 6-((quinolin-2-ylmethylene)amino)-2H-chromen-2-one obtained by a derivatization of natural compound coumarin. The structural characterization in solution was done by NMR techniques, UV-Vis and cyclic voltammetry. The potential antibacterial effect of [Cu(NN1)2](ClO4), was assessed for F. psychrophilum isolated 10094. F. psychrophilum is a Gram-negative bacterium which causes diseases such as bacterial cold-water disease and rainbow trout fry syndrome, causing large economic losses in the freshwater salmonid aquaculture industry. This complex show to have antibacterial activity against F. psychrophilum 10094 at non-cytotoxic concentration in cell line derived from trout (F. psychrophilum 10094 IC50 16.0 \u00b1 0.9; RT-GUT IC50 53.0 \u00b1 3.1 \u00b5g\/mL).<\/jats:p>","DOI":"10.3390\/molecules25143183","type":"journal-article","created":{"date-parts":[[2020,7,22]],"date-time":"2020-07-22T05:10:30Z","timestamp":1595394630000},"page":"3183","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["New Copper(I) Complex with a Coumarin as Ligand with Antibacterial Activity against Flavobacterium psychrophilum"],"prefix":"10.3390","volume":"25","author":[{"given":"Maialen","family":"Aldabaldetrecu","sequence":"first","affiliation":[{"name":"Laboratory of Coordination Compounds and Supramolecularity, Faculty of Chemistry and Biology, University of Santiago of Chile, 9170002 Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mick","family":"Parra","sequence":"additional","affiliation":[{"name":"Laboratory of Natural Products Chemistry, Centre of Aquatic Biotechnology, Faculty of Chemistry and Biology, University of Santiago of Chile, 9170002 Santiago, Chile"},{"name":"Laboratory of Bacterial Metagenomic, Centre of Aquatic Biotechnology, Faculty of Chemistry and Biology, University of Santiago of Chile, 9170002 Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarita","family":"Soto","sequence":"additional","affiliation":[{"name":"Laboratory of Biochemistry and Oral Biology, Faculty of Odontology, University of Chile, 8380000 Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4689-3874","authenticated-orcid":false,"given":"Pablo","family":"Arce","sequence":"additional","affiliation":[{"name":"Laboratory of Coordination Compounds and Supramolecularity, Faculty of Chemistry and Biology, University of Santiago of Chile, 9170002 Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4573-6460","authenticated-orcid":false,"given":"Mario","family":"Tello","sequence":"additional","affiliation":[{"name":"Laboratory of Bacterial Metagenomic, Centre of Aquatic Biotechnology, Faculty of Chemistry and Biology, University of Santiago of Chile, 9170002 Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9827-5162","authenticated-orcid":false,"given":"Juan","family":"Guerrero","sequence":"additional","affiliation":[{"name":"Laboratory of Coordination Compounds and Supramolecularity, Faculty of Chemistry and Biology, University of Santiago of Chile, 9170002 Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda","family":"Modak","sequence":"additional","affiliation":[{"name":"Laboratory of Natural Products Chemistry, Centre of Aquatic Biotechnology, Faculty of Chemistry and Biology, University of Santiago of Chile, 9170002 Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,7,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1046\/j.1365-2761.2003.00488.x","article-title":"Flavobacterium psychrophilum infections in salmonid fish","volume":"26","author":"Nematollahi","year":"2003","journal-title":"J. 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