{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:01:37Z","timestamp":1790625697971,"version":"4.1.0"},"reference-count":77,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2020,11,6]],"date-time":"2020-11-06T00:00:00Z","timestamp":1604620800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>In the scenario of promising sources of functional foods and preventive drugs, microalgae and cyanobacteria are attracting global attention. In this review, the current and future role of microalgae as natural sources of functional foods for human health and, in particular, for oral health has been reported and discussed in order to provide an overview on the state of art on microalgal effects on human oral health. It is well known that due to their richness in high-valuable products, microalgae offer good anti-inflammatory, antioxidant, antitumoral, anti-glycemic, cholesterol-lowering, and antimicrobial activity. Moreover, the findings of the present research show that microalgae could also have a significant impact on oral health: several studies agree on the potential application of microalgae for oral cancer prevention as well as for the treatment of chronic periodontitis and different oral diseases with microbial origin. Thus, beneficial effects of microalgae could be implemented in different medical fields. Microalgae and cyanobacteria could represent a potential natural alternative to antibiotic, antiviral, or antimycotic therapies, as well as a good supplement for the prevention and co-adjuvant treatment of different oral diseases. Nevertheless, more studies are required to identify strains of interest, increase overall functioning, and make safe, effective products available for the whole population.<\/jats:p>","DOI":"10.3390\/molecules25215164","type":"journal-article","created":{"date-parts":[[2020,11,8]],"date-time":"2020-11-08T20:23:35Z","timestamp":1604867015000},"page":"5164","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Cyanobacteria and Microalgae as Sources of Functional Foods to Improve Human General and Oral Health"],"prefix":"10.3390","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1723-106X","authenticated-orcid":false,"given":"Gianmaria Fabrizio","family":"Ferrazzano","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Reproductive Sciences and Oral Sciences, School of Paediatric Dentistry, University of Naples \u201cFederico II\u201d, 80131 Naples, Italy"},{"name":"Unesco Chair on Health Education and Sustainable Development, University of Naples, \u201cFederico II\u201d, 80121 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4190-0043","authenticated-orcid":false,"given":"Cristina","family":"Papa","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive Sciences and Oral Sciences, School of Paediatric Dentistry, University of Naples \u201cFederico II\u201d, 80131 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3018-7921","authenticated-orcid":false,"given":"Antonino","family":"Pollio","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Naples \u201cFederico II\u201d, 80126 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aniello","family":"Ingenito","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive Sciences and Oral Sciences, School of Paediatric Dentistry, University of Naples \u201cFederico II\u201d, 80131 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giancarla","family":"Sangianantoni","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive Sciences and Oral Sciences, School of Paediatric Dentistry, University of Naples \u201cFederico II\u201d, 80131 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2648-175X","authenticated-orcid":false,"given":"Tiziana","family":"Cantile","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive Sciences and Oral Sciences, School of Paediatric Dentistry, University of Naples \u201cFederico II\u201d, 80131 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,11,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1078\/1438-4639-00045","article-title":"Biochemical and pharmacological investigations of selected cyanobacteria","volume":"203","author":"Mundt","year":"2001","journal-title":"Int. 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