{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:58:09Z","timestamp":1787029089408,"version":"build-2736575974"},"reference-count":104,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T00:00:00Z","timestamp":1611532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Plants have had historical significance in medicine since the beginning of civilization. The oldest medical pharmacopeias of the African, Arabian, and Asian countries solely utilize plants and herbs to treat pain, oral diseases, skin diseases, microbial infections, multiple types of cancers, reproductive disorders among a myriad of other ailments. The World Health Organization (WHO) estimates that over 65% of the world population solely utilize botanical preparations as medicine. Due to the abundance of plants, plant-derived medicines are more readily accessible, affordable, convenient, and have safer side-effect profiles than synthetic drugs. Plant-based decoctions have been a significant part of Jamaican traditional folklore medicine. Jamaica is of particular interest because it has approximately 52% of the established medicinal plants that exist on earth. This makes the island particularly welcoming for rigorous scientific research on the medicinal value of plants and the development of phytomedicine thereof. Viral infections caused by the human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2), hepatitis virus B and C, influenza A virus, and the severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) present a significant global burden. This is a review of some important Jamaican medicinal plants, with particular reference to their antiviral activity.<\/jats:p>","DOI":"10.3390\/molecules26030607","type":"journal-article","created":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T09:59:40Z","timestamp":1611568780000},"page":"607","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Antiviral Activity of Jamaican Medicinal Plants and Isolated Bioactive Compounds"],"prefix":"10.3390","volume":"26","author":[{"given":"Henry","family":"Lowe","sequence":"first","affiliation":[{"name":"Biotech R &amp; D Institute, University of the West Indies, Mona, 99999 Kingston, Jamaica"},{"name":"Vilotos Pharmaceuticals Inc., Baltimore, MD 21202, USA"},{"name":"Flavocure Biotech Inc., Baltimore, MD 21202, USA"},{"name":"Institute of Human Virology (IHV), University of Maryland School of Medicine, Baltimore, MD 21201, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blair","family":"Steele","sequence":"additional","affiliation":[{"name":"Biotech R &amp; D Institute, University of the West Indies, Mona, 99999 Kingston, Jamaica"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Bryant","sequence":"additional","affiliation":[{"name":"Biotech R &amp; D Institute, University of the West Indies, Mona, 99999 Kingston, Jamaica"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emadelden","family":"Fouad","sequence":"additional","affiliation":[{"name":"Physics Department, Florida Polytechnic Institute, Lakeland, FL 33805, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9683-6192","authenticated-orcid":false,"given":"Ngeh","family":"Toyang","sequence":"additional","affiliation":[{"name":"Vilotos Pharmaceuticals Inc., Baltimore, MD 21202, USA"},{"name":"Flavocure Biotech Inc., Baltimore, MD 21202, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilfred","family":"Ngwa","sequence":"additional","affiliation":[{"name":"Physics Department, Florida Polytechnic Institute, Lakeland, FL 33805, USA"},{"name":"Brigham and Women\u2019s Hospital, Dana-Faber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,1,25]]},"reference":[{"key":"ref_1","unstructured":"Robinson, M.M., and Zhang, X. 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