{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T05:50:28Z","timestamp":1787637028915,"version":"build-2736575974"},"reference-count":173,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2021,1,30]],"date-time":"2021-01-30T00:00:00Z","timestamp":1611964800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006109","name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV","doi-asserted-by":"publisher","award":["VEGA 1\/0589\/19"],"award-info":[{"award-number":["VEGA 1\/0589\/19"]}],"id":[{"id":"10.13039\/501100006109","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>During the time of the novel coronavirus disease 2019 (COVID-19) pandemic, it has been crucial to search for novel antiviral drugs from plants and well as other natural sources as alternatives for prophylaxis. This work reviews the antiviral potential of plant extracts, and the results of previous research for the treatment and prophylaxis of coronavirus disease and previous kinds of representative coronaviruses group. Detailed descriptions of medicinal herbs and crops based on their origin native area, plant parts used, and their antiviral potentials have been conducted. The possible role of plant-derived natural antiviral compounds for the development of plant-based drugs against coronavirus has been described. To identify useful scientific trends, VOSviewer visualization of presented scientific data analysis was used.<\/jats:p>","DOI":"10.3390\/molecules26030727","type":"journal-article","created":{"date-parts":[[2021,1,30]],"date-time":"2021-01-30T21:15:51Z","timestamp":1612041351000},"page":"727","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["COVID-19 Prophylaxis Efforts Based on Natural Antiviral Plant Extracts and Their Compounds"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4219-9292","authenticated-orcid":false,"given":"Oksana","family":"Sytar","sequence":"first","affiliation":[{"name":"Department of Plant Physiology, Slovak University of Agriculture, A. Hlinku 2, 94976 Nitra, Slovakia"},{"name":"Department of Plant Biology, Institute of Biology, Kiev National, University of Taras Shevchenko, Volodymyrska, 64, 01033 Kyiv, Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3470-6100","authenticated-orcid":false,"given":"Marian","family":"Brestic","sequence":"additional","affiliation":[{"name":"Department of Plant Physiology, Slovak University of Agriculture, A. Hlinku 2, 94976 Nitra, Slovakia"},{"name":"Department of Botany and Plant Physiology, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamycka 129, 16500 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9027-1976","authenticated-orcid":false,"given":"Shokoofeh","family":"Hajihashemi","sequence":"additional","affiliation":[{"name":"Plant Biology Department, Faculty of Science, Behbahan Khatam Alanbia University of Technology, 47189-63616 Khuzestan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4114-6909","authenticated-orcid":false,"given":"Milan","family":"Skalicky","sequence":"additional","affiliation":[{"name":"Department of Botany and Plant Physiology, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamycka 129, 16500 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Kube\u0161","sequence":"additional","affiliation":[{"name":"Department of Botany and Plant Physiology, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamycka 129, 16500 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Lamilla-Tamayo","sequence":"additional","affiliation":[{"name":"Department of Botany and Plant Physiology, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamycka 129, 16500 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulkar","family":"Ibrahimova","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biology and Biotechnology, Azerbaijan National Academy of Sciences, Matbuat Avenue 2A, Az 1073 Baku, Azerbaijan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayyara","family":"Ibadullayeva","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biology and Biotechnology, Azerbaijan National Academy of Sciences, Matbuat Avenue 2A, Az 1073 Baku, Azerbaijan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0121-0715","authenticated-orcid":false,"given":"Marco","family":"Landi","sequence":"additional","affiliation":[{"name":"Department of Agriculture, Food and Environment, University of Pisa, 56126 Behbahan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,1,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.bj.2020.04.007","article-title":"COVID-19: The first documented coronavirus pandemic in history","volume":"43","author":"Liu","year":"2020","journal-title":"Biomed. 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