{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T15:12:17Z","timestamp":1792422737545,"version":"4.5.0"},"reference-count":122,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T00:00:00Z","timestamp":1626652800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Science and Technology","award":["MOST 109-2622-E-007-008; MOST 109-2321-B-182A-006 -"],"award-info":[{"award-number":["MOST 109-2622-E-007-008; MOST 109-2321-B-182A-006 -"]}]},{"name":"Chang Gung Memorial Hospital Research Grant","award":["CMRPG3H1661; CMRPG3K0781"],"award-info":[{"award-number":["CMRPG3H1661; CMRPG3K0781"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Infertility is a state of the male or female reproductive system that is defined as the failure to achieve pregnancy even after 12 or more months of regular unprotected sexual intercourse. Assisted reproductive technology (ART) plays a crucial role in addressing infertility. Various ART are now available for infertile couples. Fertilization in vitro (IVF), intracytoplasmic sperm injection (ICSI) and intrauterine insemination (IUI) are the most common techniques in this regard. Various microfluidic technologies can incorporate various ART procedures such as embryo and gamete (sperm and oocyte) analysis, sorting, manipulation, culture and monitoring. Hence, this review intends to summarize the current knowledge about the application of this approach towards cell biology to enhance ART.<\/jats:p>","DOI":"10.3390\/molecules26144354","type":"journal-article","created":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T10:07:37Z","timestamp":1626689257000},"page":"4354","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["A Review on Microfluidics: An Aid to Assisted Reproductive Technology"],"prefix":"10.3390","volume":"26","author":[{"given":"Anand Baby","family":"Alias","sequence":"first","affiliation":[{"name":"Institute of NanoEngineering and MicroSystems, National Tsing Hua University, Hsinchu 30013, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Yuan","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan"},{"name":"Department of Obstetrics and Gynecology, Chang Gung University and College of Medicine, Taoyuan 33305, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6631-780X","authenticated-orcid":false,"given":"Da-Jeng","family":"Yao","sequence":"additional","affiliation":[{"name":"Institute of NanoEngineering and MicroSystems, National Tsing Hua University, Hsinchu 30013, Taiwan"},{"name":"Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,7,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Pourakbari, R., Ahmadi, H., Yousefi, M., and Aghebati-Maleki, L. 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