{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T02:44:01Z","timestamp":1791686641373,"version":"4.3.4"},"reference-count":101,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T00:00:00Z","timestamp":1627430400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["RTI2018-096626-B-I00"],"award-info":[{"award-number":["RTI2018-096626-B-I00"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Off-flavors produced by undesirable microbial spoilage are a major concern in wineries, as they affect wine quality. This situation is worse in warm areas affected by global warming because of the resulting higher pHs in wines. Natural biotechnologies can aid in effectively controlling these processes, while reducing the use of chemical preservatives such as SO2. Bioacidification reduces the development of spoilage yeasts and bacteria, but also increases the amount of molecular SO2, which allows for lower total levels. The use of non-Saccharomyces yeasts, such as Lachancea thermotolerans, results in effective acidification through the production of lactic acid from sugars. Furthermore, high lactic acid contents (&gt;4 g\/L) inhibit lactic acid bacteria and have some effect on Brettanomyces. Additionally, the use of yeasts with hydroxycinnamate decarboxylase (HCDC) activity can be useful to promote the fermentative formation of stable vinylphenolic pyranoanthocyanins, reducing the amount of ethylphenol precursors. This biotechnology increases the amount of stable pigments and simultaneously prevents the formation of high contents of ethylphenols, even when the wine is contaminated by Brettanomyces.<\/jats:p>","DOI":"10.3390\/molecules26154571","type":"journal-article","created":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T11:12:52Z","timestamp":1627470772000},"page":"4571","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Non-Saccharomyces as Biotools to Control the Production of Off-Flavors in Wines"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1275-6721","authenticated-orcid":false,"given":"Antonio","family":"Morata","sequence":"first","affiliation":[{"name":"enotecUPM, Departamento de Qu\u00edmica y Tecnolog\u00eda de Alimentos, Universidad Polit\u00e9cnica de Madrid, Avenida Puerta de Hierro 2, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0399-4744","authenticated-orcid":false,"given":"Iris","family":"Loira","sequence":"additional","affiliation":[{"name":"enotecUPM, Departamento de Qu\u00edmica y Tecnolog\u00eda de Alimentos, Universidad Polit\u00e9cnica de Madrid, Avenida Puerta de Hierro 2, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"enotecUPM, Departamento de Qu\u00edmica y Tecnolog\u00eda de Alimentos, Universidad Polit\u00e9cnica de Madrid, Avenida Puerta de Hierro 2, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9113-0414","authenticated-orcid":false,"given":"Carlos","family":"Escott","sequence":"additional","affiliation":[{"name":"enotecUPM, Departamento de Qu\u00edmica y Tecnolog\u00eda de Alimentos, Universidad Polit\u00e9cnica de Madrid, Avenida Puerta de Hierro 2, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,7,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1007\/s00253-006-0828-1","article-title":"Modulation of volatile sulfur compounds by wine yeast","volume":"74","author":"Swiegers","year":"2007","journal-title":"Appl. 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