{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T01:28:28Z","timestamp":1772501308895,"version":"3.50.1"},"reference-count":55,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2021,9,12]],"date-time":"2021-09-12T00:00:00Z","timestamp":1631404800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>The main objective of this work was to contribute to the reduction in the contamination of phenolic compounds contained in margin by an adsorption process on two types of raw bentonite. The margin used in the studies was collected from a semi-modern oil mill located in the Nador\u2013Morocco region. The results of the physico-chemical analyses showed that the effluents of the oil mills showed that they are highly polluted, particularly in terms of the total suspended solids (TSS), chemical oxygen demand (COD), and iron content of around 154.82 (mg\/L), and copper content of 31.72 (mg\/L). The mineralogy of bentonites studied by X-ray diffraction (XRD) reveals the existence of two types of montmorillonite; theoretically, the diffraction peak (001) of the montmorillonite appears at 15 \u00c5, with a basal spacing that corresponds to a calcium pole, and the diffraction peak (001) appears at 12\u00c5, with a basal spacing that corresponds to a sodium pole. The specific surface area of the bentonite used is characterized by a large specific surface area, varying between 127.62 m2\u00b7g\u22121 and 693.04 m2\u00b7g\u22121, which is due to the presence of hydrated interleaved cations. This surface is likely to increase in aqueous solution depending on the solid\/liquid ratio that modulates the degree of hydration. With a high cation exchange capacity (CEC) (146.54 meq\/100 g), samples of margin mixed with raw bentonites at different percentages vary between 5% and 100%. The potential of Moroccan bentonite for the phenol adsorption of 9.17 (g\/L) from aqueous solutions was investigated. Adsorption tests have confirmed the effectiveness of these natural minerals in reducing phenolic compounds ranging from 8.72% to 76.23% contained in the margin and the efficiency of heavy metal retention through microelements on raw bentonites. The very encouraging results obtained in this work could aid in the application of adsorption for the treatment of margin.<\/jats:p>","DOI":"10.3390\/molecules26185528","type":"journal-article","created":{"date-parts":[[2021,9,12]],"date-time":"2021-09-12T21:48:01Z","timestamp":1631483281000},"page":"5528","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Valorization of Moroccan Bentonite Deposits: \u201cPurification and Treatment of Margin by the Adsorption Process\u201d"],"prefix":"10.3390","volume":"26","author":[{"given":"Hanane","family":"Ait Hmeid","sequence":"first","affiliation":[{"name":"Laboratory Observatory of the Marchica Lagoon of Nador and Limiting Regions (OLMAN-RL), Multidisciplinary Faculty of Nador, Mohamed 1st University, Nador 60700, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustapha","family":"Akodad","sequence":"additional","affiliation":[{"name":"Laboratory Observatory of the Marchica Lagoon of Nador and Limiting Regions (OLMAN-RL), Multidisciplinary Faculty of Nador, Mohamed 1st University, Nador 60700, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8976-7731","authenticated-orcid":false,"given":"Mourad","family":"Baghour","sequence":"additional","affiliation":[{"name":"Laboratory Observatory of the Marchica Lagoon of Nador and Limiting Regions (OLMAN-RL), Multidisciplinary Faculty of Nador, Mohamed 1st University, Nador 60700, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4575-0871","authenticated-orcid":false,"given":"Abdelmajid","family":"Moumen","sequence":"additional","affiliation":[{"name":"Laboratory Observatory of the Marchica Lagoon of Nador and Limiting Regions (OLMAN-RL), Multidisciplinary Faculty of Nador, Mohamed 1st University, Nador 60700, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Skalli","sequence":"additional","affiliation":[{"name":"Laboratory Observatory of the Marchica Lagoon of Nador and Limiting Regions (OLMAN-RL), Multidisciplinary Faculty of Nador, Mohamed 1st University, Nador 60700, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghizlane","family":"Azizi","sequence":"additional","affiliation":[{"name":"Laboratory Observatory of the Marchica Lagoon of Nador and Limiting Regions (OLMAN-RL), Multidisciplinary Faculty of Nador, Mohamed 1st University, Nador 60700, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hicham","family":"Gueddari","sequence":"additional","affiliation":[{"name":"Laboratory Observatory of the Marchica Lagoon of Nador and Limiting Regions (OLMAN-RL), Multidisciplinary Faculty of Nador, Mohamed 1st University, Nador 60700, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mostapha","family":"Maach","sequence":"additional","affiliation":[{"name":"Laboratory Observatory of the Marchica Lagoon of Nador and Limiting Regions (OLMAN-RL), Multidisciplinary Faculty of Nador, Mohamed 1st University, Nador 60700, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mimoun","family":"Aalaoul","sequence":"additional","affiliation":[{"name":"Laboratory of Applied Geosciences, Faculty of Sciences of Oujda, Mohamed 1st University, Oujda 60000, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Anjjar","sequence":"additional","affiliation":[{"name":"Laboratory of Georessources and Environment (GRE), Faculty of Science and Technology, University Sidi Mohamed Ben Abdellah, B.P.2202-Imouzzer Road, Fes 30000, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7550-4287","authenticated-orcid":false,"given":"Lahcen","family":"Daoudi","sequence":"additional","affiliation":[{"name":"Laboratory of Geosciences Georesources and Environment, Department of Geology, Faculty of Science and Technology University Cadi Ayyad, Marrakech 40000, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,9,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e02386","DOI":"10.1016\/j.heliyon.2019.e02386","article-title":"Pollution estimation from olive mills wastewater in Jordan","volume":"5","author":"Khdair","year":"2019","journal-title":"Heliyon"},{"key":"ref_2","first-page":"488","article-title":"Valorisation of natural mineral substances (NMS) at adsorption techniques: Case of olive oil mill waste waters","volume":"7","author":"Jeddi","year":"2016","journal-title":"J. Mater. Environ. Sci."},{"key":"ref_3","first-page":"2247","article-title":"Adsorption du ph\u00e9nol en milieu aqueux par une pyrophyllite marocaine brute et trait\u00e9e (Adsorption of phenol in aqueous medium by a raw and treated moroccan pyrophyllite)","volume":"6","author":"Benabdallah","year":"2015","journal-title":"J. Mater. Environ. Sci."},{"key":"ref_4","first-page":"121","article-title":"Physico-chemical and microbiological study of oil mill wastewater (OMW) from three different regions of Morocco (Ouazzane, Fes Boulman and B\u00e9ni Mellal)","volume":"5","author":"Esmail","year":"2014","journal-title":"J. Mater. Environ. Sci."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.biortech.2012.12.119","article-title":"Anaerobic co-digestion of solid waste: Effect of increasing organic loading rates and characterization of the solubilised organic matter","volume":"130","author":"Ganesh","year":"2013","journal-title":"Bioresour. Technol."},{"key":"ref_6","first-page":"20","article-title":"Tables of composition and nutritive value of feedstuffs for rabbits: First proposal from European working group","volume":"6","author":"Perez","year":"1998","journal-title":"World Rabbit. Sci."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"3756","DOI":"10.1021\/es990743o","article-title":"Sorption of ionizable organic solutes by surfactant-modified zeolite","volume":"34","author":"Li","year":"2000","journal-title":"Environ. Sci. Technol."},{"key":"ref_8","first-page":"1223","article-title":"Feasibility of olive mill wastewater treatment by multi-soil-layering ecotechnology","volume":"9","author":"Ouazzani","year":"2018","journal-title":"J. Mater. Environ. Sci."},{"key":"ref_9","first-page":"10","article-title":"Activation of Jordanian bentonite by hydrochloric acid and its potential for olive mill wastewater enhanced treatment","volume":"2018","year":"2018","journal-title":"J. Chem."},{"key":"ref_10","first-page":"101","article-title":"Adsorption of lead and copper by a carbon black and sodium bentonite composite material: Study on adsorption isotherms and kinetics","volume":"38","author":"Matthews","year":"2019","journal-title":"Iran. J. Chem. Chem. Eng."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"558","DOI":"10.4314\/ijbcs.v12i1.43","article-title":"Adsorption d\u2019un colorant basique, Bleu de M\u00e9thyl\u00e8ne, en solution aqueuse, sur un bioadsorbant issu de d\u00e9chets agricoles de Cucumeropsis mannii Naudin","volume":"12","author":"Kifuani","year":"2018","journal-title":"Int. J. Biol. Chem. Sci."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1289\/ehp.8983145","article-title":"Adsorption of organic chemicals in soils","volume":"83","author":"Calvet","year":"1989","journal-title":"Environ. Health Perspect."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1006\/jcis.1999.6247","article-title":"Effect of pore clogging on kinetics of lead uptake by clinoptilolite","volume":"215","author":"Inglezakis","year":"1999","journal-title":"J. Colloid Interface Sci."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0001-8686(00)00082-8","article-title":"Adsorption\u2014From theory to practice","volume":"93","author":"Dabrowski","year":"2001","journal-title":"Adv. Colloid Interface Sci."},{"key":"ref_15","unstructured":"Iboukhoulef, H. (2014). Traitement des Margines des Huileries d\u2019olive par les Proc\u00e9d\u00e9s d\u2019oxydation Avanc\u00e9e Bas\u00e9 sur le Syst\u00e8me Fenton-Like (H2 O2\/Cu). [Ph.D. Thesis, University Mouloud Mammer]."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Jannah, M., Mulyati, S., Rosnelly, C.M., and Muchtar, S. (2021, January 27). The influences of operating conditions on the removal of Fe (II) in water by adsorption using bentonite as a low-cost adsorbent. Proceedings of the IOP Conference Series: Materials Science and Engineering IOP Publishing, Songkhla, Thailand.","DOI":"10.1088\/1757-899X\/1087\/1\/012055"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"13368","DOI":"10.1039\/D0NJ02259D","article-title":"Removal of paraquat from aqueous solutions by a bentonite modified zero-valent iron adsorbent","volume":"44","author":"Dehgani","year":"2020","journal-title":"New J. Chem."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.matpr.2019.04.007","article-title":"Particle size distribution and statistic analysis of the grain size messinian bentonite from the kert bassin (northern Morocco)","volume":"13","author":"Akodad","year":"2019","journal-title":"Mater. Today Proc."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Ait Hmeid, H., Akodad, M., Aalaoul, M., Baghour, M., Moumen, A., Skalli, A., Anjjar, A., Conti, P., Sfalanga, A., and Khyabani, R.F. (2020). Clay mineralogy, chemical and geotechnical characterization of bentonite from Beni Bou Ifrour Massif (the Eastern Rif, Morocco). Geol. Soc. Lond., 502.","DOI":"10.1144\/SP502-2019-25"},{"key":"ref_20","first-page":"38714","article-title":"Petrographic, mineralogical and geochemical characterization of volcanic products from north-eastmorocco","volume":"10","author":"Akodad","year":"2020","journal-title":"Int. J. Dev. Res."},{"key":"ref_21","first-page":"1","article-title":"British geological survey: Industrial minerals laboratory manual","volume":"124","author":"Inglethorpe","year":"1993","journal-title":"J. Mat."},{"key":"ref_22","first-page":"74","article-title":"Mineralogical and chemical characterization of various bentonite and smectite-rich clay materials\u2014Part A: Comparison and development of mineralogical characterization methods\u2014Part B: Mineralogical and chemical characterization of clay materials","volume":"52","author":"Kumpulainen","year":"2010","journal-title":"Posiva. Oy."},{"key":"ref_23","unstructured":"Khenifi, A. (2010). Elaboration de Materiaux a Base d\u2019Argiles, Caracterisation, et Application a l\u2019elimination des Polluants Organiques. [Ph.D. Thesis, University of Science and Technology of Oran Mohamed Boudiaf]."},{"key":"ref_24","first-page":"105","article-title":"Nonyl-and dodecylamines intercalated bentonite and illite from Turkey","volume":"23","author":"Akcay","year":"1999","journal-title":"Turk. J. Chem."},{"key":"ref_25","unstructured":"Bouras, O. (2003). Proprietes Adsorbantes d\u2019Argiles Pontees Organophiles: Synthese et Caracterisation. [Ph.D. Thesis, University of Limoges]."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s12034-007-0042-5","article-title":"Instrumental characterization of clay by XRF, XRD and FTIR","volume":"30","author":"Nayak","year":"2007","journal-title":"Bull. Mater. Sci."},{"key":"ref_27","unstructured":"Zahaf, F. (2017). Etude Structurale des Argiles Modifi\u00e9es Appliqu\u00e9es \u00e0 l\u2019Adsorption des Polluants. [Ph.D. Thesis, University Mustapha Stambouli of Mascara]."},{"key":"ref_28","first-page":"1","article-title":"Spectroscopic characterization of bentonite","volume":"4","author":"Endo","year":"2017","journal-title":"J. Lasers Opt. Photonics"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.desal.2006.04.060","article-title":"Development of an Algerian material montmorillonite clay. Adsorption of phenol, 2-dichlorophenol and 2,4,6-trichlorophenol from aqueous solutions onto montmorillonite exchanged with transition metal complexes","volume":"206","author":"Boufatit","year":"2007","journal-title":"Desalination"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/j.jhazmat.2007.09.070","article-title":"A comparative study of the adsorption and desorption of o-xylene onto bentonite clay and alumina","volume":"153","author":"Zaitan","year":"2008","journal-title":"J. Hazard. Mater."},{"key":"ref_31","first-page":"63","article-title":"Synthesis and catalytic activity of vanadia-doped iron-pillared clays for cyclohexene epoxidation","volume":"6","author":"Brahimi","year":"2015","journal-title":"Res. J. Pharm. Biol. Chem. Sci."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/ppsc.201100030","article-title":"Characterization of nano-porous bentonite (montmorillonite) particles using FTIR and BET-BJH analyses","volume":"28","year":"2011","journal-title":"Part. Syst. Charact."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"101155","DOI":"10.1016\/j.jwpe.2020.101155","article-title":"Study of the adsorption\/desorption of MB dye solution using bentonite adsorbent coating","volume":"34","author":"Momina","year":"2020","journal-title":"J. Water Process. Eng."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0169-1317(01)00101-6","article-title":"Mineralogy and firing characteristics of a clay from the valley of Ourika (Morocco)","volume":"21","author":"Hajjaji","year":"2002","journal-title":"Appl. Clay Sci."},{"key":"ref_35","first-page":"1","article-title":"Experimental design and modeling of removal of organic matter and nutrients in the OMW by calcium bentonite","volume":"234","author":"Akodad","year":"2021","journal-title":"E3S Web Conf."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.clay.2008.07.006","article-title":"Characterization of Al, Cr-pillared clays and CO oxidation","volume":"43","author":"Tomul","year":"2009","journal-title":"Appl. Clay Sci."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/j.1747-0765.2007.00128.x","article-title":"Characteristics of wastewater treatment using a multi-soil-layering system in relation to wastewater contamination levels and hydraulic loading rates","volume":"53","author":"Masunaga","year":"2007","journal-title":"Soil Sci. Plant Nut."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/j.1747-0765.2007.00118.x","article-title":"Characteristics of CO2, CH4 and N2O emissions from a multi-soil-layering system during wastewater treatment","volume":"53","author":"Masunaga","year":"2007","journal-title":"Soil Sci. Plant Nut."},{"key":"ref_39","first-page":"53","article-title":"Caract\u00e9risation des margines issues d\u2019une huilerie moderne et essais de leur traitement par coagulation-floculation par la chaux et le sulfate d\u2019aluminium","volume":"21","author":"Achak","year":"2008","journal-title":"J. Water Sci."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1080\/00380768.2011.590944","article-title":"Quantitative evaluation of treatment processes and mechanisms of organic matter, phosphorus, and nitrogen removal in a multi-soil-layering system","volume":"57","author":"Sato","year":"2011","journal-title":"Soil Sci. Plant Nutr."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.ecoleng.2018.04.003","article-title":"Optimization of hydraulic efficiency and wastewater treatment performances using a new design of vertical flow Multi-Soil-Layering (MSL) technology","volume":"117","author":"Latrach","year":"2018","journal-title":"Ecol. Eng."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1016\/j.biortech.2007.03.022","article-title":"Reduction of organic pollutants in olive mill wastewater by using different mineral substrates as adsorbents","volume":"99","author":"Santi","year":"2008","journal-title":"Bioresour. Technol."},{"key":"ref_43","unstructured":"Moore, D.M., and Reynolds, R.C. (1989). X-ray Diffraction and the Identification and Analysis of Clay Minerals, Oxford University Press (OUP)."},{"key":"ref_44","first-page":"136","article-title":"Un nouvel essai d\u2019identification des sols-l\u2019essai au bleu de methylene","volume":"88","author":"Lan","year":"1977","journal-title":"Bull Liaison Lab Ponts Chauss"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.clay.2015.05.020","article-title":"Identification of clay minerals in mixtures subjected to differential thermal and thermogravimetry analyses and methylene blue adsorption tests","volume":"114","author":"Arab","year":"2015","journal-title":"Appl. Clay Sci."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1016\/j.soilbio.2008.11.017","article-title":"Genotypic variability in P use efficiency for symbiotic nitrogen fixation is associated with variation of proton efflux in cowpea rhizosphere","volume":"41","author":"Alkama","year":"2009","journal-title":"Soil Biol. Biochem."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1080\/00380768.2014.974480","article-title":"Soil science and plant nutrition removal of bacterial indicators and pathogens from domestic wastewater by the multi-soil-layering(MSL) system","volume":"61","author":"Latrach","year":"2015","journal-title":"Soil Sci. Plant Nut."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"139","DOI":"10.3390\/agriculture2020139","article-title":"Low soil phosphorus availability increases acid phosphatases activities and affects partitioning in nodules, seeds and rhizosphere of Phaseolus vulgaris","volume":"2","author":"Bargaz","year":"2012","journal-title":"Agriculture"},{"key":"ref_49","unstructured":"American Public Health Association, American Water Works Association, Water Pollution Control Federation, and Water Environment Federation (1912). Standard Methods for the Examination of Water and Wastewater, American Public Health Association."},{"key":"ref_50","unstructured":"Rodier, J., Geoffray, C., and Rodi, L. (1984). L\u2019Analyse de l\u2019Eau: Eaux Naturelles, Eaux R\u00e9siduaires, Eau de Mer: Chimie, Physico-Chimie, Bact\u00e9riologie, Biologie, DUNOD."},{"key":"ref_51","unstructured":"Macheix, J.J., Fleuriet, A., and Billo, J.A. (1990). Fruit Phenolics, CRC Press Inc."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1080\/10408399109527552","article-title":"Phenolic compounds and polyphenoloxidase in relation to browning in grapes and wines","volume":"30","author":"Macheix","year":"1991","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"01002","DOI":"10.1051\/e3sconf\/202124001002","article-title":"Bioaccumulation and health risk assessment of trace elements in Mytilus galloprovincialis as sea food in the Al Hoceima coasts (Morocco)","volume":"240","author":"Azizi","year":"2021","journal-title":"E3S Web Conf."},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Azizi, G., Layachi, M., Akodad, M., Ngadi, H., Baghour, M., Skalli, A., Ghalit, M., Gharibi, E., and Moumen, A. (2020). Assessment of heavy metals (Fe, Cu and Ni) contamination of seawater and mussel, Mytilus Galloprovincialis, from Al Hoceima Moroccan coasts: Heavy metal concentrations in Mytilus Galloprovincialis. Geo-IT Water Resour., 1\u20136.","DOI":"10.1145\/3399205.3399229"},{"key":"ref_55","first-page":"100","article-title":"A new approach for assessing the absorption of disposable baby diapers and superabsorbent polymers: A comparative study","volume":"8","author":"Bachra","year":"2020","journal-title":"Results Mater."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/26\/18\/5528\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:01:12Z","timestamp":1760166072000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/26\/18\/5528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,12]]},"references-count":55,"journal-issue":{"issue":"18","published-online":{"date-parts":[[2021,9]]}},"alternative-id":["molecules26185528"],"URL":"https:\/\/doi.org\/10.3390\/molecules26185528","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,12]]}}}