{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T20:51:14Z","timestamp":1775595074460,"version":"3.50.1"},"reference-count":41,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T00:00:00Z","timestamp":1637020800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Stinging nettle (Urtica dioica L.) is a good source of biologically active compounds with proven beneficial health effects. This study aimed to investigate the effect of nettle herb supplementation on chemical composition, including the content of selected minerals and pigments, the in vitro glycemic response, and the cooking and sensory quality of extruded pasta. Tagliatelle-shaped pasta was produced under semi-technical scale by partial replacement of durum wheat semolina with 0, 1, 2, 3, 4, and 5% of lyophilized nettle. The partial substitution with freeze-dried nettle caused a statistically significant (p \u2264 0.05) increase in the content of minerals, especially calcium, iron, potassium, and magnesium in the products. The calcium content in the pasta fortified with 5%-addition of stinging nettle was 175.9 mg 100 g\u22121 and this concentration was 5.8 times higher than in the control sample. At the same time, high content of chlorophylls and carotenoids (237.58 \u00b5g g\u22121 and 13.35 \u00b5g g\u22121, respectively) was noticed. Enriching pasta with a 0\u20135% addition of stinging nettle resulted in a statistically significant (p \u2264 0.05) increase in the content of the total dietary fiber (TDF) (from 5.1 g 100 g\u22121 to 8.82 g 100 g\u22121) and the insoluble dietary fiber (IDF) (from 2.29 g 100 g\u22121 to 5.63 g 100 g\u22121). The lowest hydrolysis index of starch (HI = 17.49%) and the lowest glycemic index (GI = 49.31%) were noted for the pasta enriched with 3% nettle.<\/jats:p>","DOI":"10.3390\/molecules26226909","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T02:42:28Z","timestamp":1637116948000},"page":"6909","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Stinging Nettle (Urtica dioica L.) as a Functional Component in Durum Wheat Pasta Production: Impact on Chemical Composition, In Vitro Glycemic Index, and Quality Properties"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7079-4836","authenticated-orcid":false,"given":"Ada","family":"Kraw\u0119cka","sequence":"first","affiliation":[{"name":"Department of Plant Food Technology and Gastronomy, University of Life Sciences in Lublin, Skromna 8 Street, 20-704 Lublin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6526-6764","authenticated-orcid":false,"given":"Aldona","family":"Sobota","sequence":"additional","affiliation":[{"name":"Department of Plant Food Technology and Gastronomy, University of Life Sciences in Lublin, Skromna 8 Street, 20-704 Lublin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urszula","family":"Pankiewicz","sequence":"additional","affiliation":[{"name":"Department of Analysis and Evaluation of Food Quality, University of Life Sciences in Lublin, Skromna 8 Street, 20-704 Lublin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4921-294X","authenticated-orcid":false,"given":"Ewelina","family":"Zieli\u0144ska","sequence":"additional","affiliation":[{"name":"Department of Analysis and Evaluation of Food Quality, University of Life Sciences in Lublin, Skromna 8 Street, 20-704 Lublin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1462-6146","authenticated-orcid":false,"given":"Piotr","family":"Zarzycki","sequence":"additional","affiliation":[{"name":"Department of Plant Food Technology and Gastronomy, University of Life Sciences in Lublin, Skromna 8 Street, 20-704 Lublin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,11,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"191","DOI":"10.21164\/pomjlifesci.78","article-title":"Stinging nettle (Urtica dioica L.)-botanical characteristics, biochemical composition and health benefits","volume":"61","author":"Jakubczyk","year":"2015","journal-title":"Pomeranian J. Life Sci."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Kregiel, D., Pawlikowska, E., and Antolak, H. (2018). Urtica spp.: Ordinary plants with extraordinary properties. Molecules, 23.","DOI":"10.3390\/molecules23071664"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.hermed.2012.11.001","article-title":"Stinging nettles leaf (Urtica dioica L.): Extraordinary vegetable medicine","volume":"3","author":"Upton","year":"2013","journal-title":"J. Herb. Med."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jff.2017.02.019","article-title":"Chemical composition of stinging nettle leaves obtained by different analytical approaches","volume":"32","author":"Popov","year":"2017","journal-title":"J. Funct. Foods"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.phymed.2012.09.016","article-title":"Lipophilic stinging nettle extracts possess potent anti-inflammatory activity, are not cytotoxic and may be superior to traditional tinctures for treating inflammatory disorders","volume":"20","author":"Johnson","year":"2013","journal-title":"Phytomedicine"},{"key":"ref_6","first-page":"4012450","article-title":"Functional Cereal Products in the Diet for Type 2 Diabetes Patients","volume":"Volume 2019","author":"Sobota","year":"2019","journal-title":"Int. J. Food Sci."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"126091","DOI":"10.1016\/j.foodchem.2019.126091","article-title":"The functional food production: Application of stinging nettle leaves and its extracts in the baking of a bread","volume":"312","year":"2020","journal-title":"Food Chem."},{"key":"ref_8","first-page":"104","article-title":"Effect of nettle leaves powder (Urtica dioica L.) addition on the quality of bread","volume":"27","author":"Man","year":"2019","journal-title":"J. Herb. Med."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"111329","DOI":"10.1016\/j.lwt.2021.111329","article-title":"Development of no-salt herbal bread using a method based on scalded flour","volume":"145","author":"Dziki","year":"2021","journal-title":"LWT Food Sci. Technol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ijgfs.2016.05.001","article-title":"Nettle cheese: Using nettle leaves (Urtica dioica) to coagulate milk in the fresh cheese making process","volume":"4","author":"Fiol","year":"2016","journal-title":"Int. J. Gastron. Food Sci."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"7723","DOI":"10.1007\/s13197-015-1916-y","article-title":"Nettle (Urtica dioica L.) extracts as functional ingredients for production of chocolates with improved bioactive composition and sensory properties","volume":"52","author":"Komes","year":"2015","journal-title":"J. Food Sci. Technol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.jff.2019.04.004","article-title":"Nanocomposite of montmorillonite\/nettle extract: A potential ingredient for functional foods development","volume":"57","author":"Rutakhli","year":"2019","journal-title":"J. Funct. Foods"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"109555","DOI":"10.1016\/j.foodres.2020.109555","article-title":"Improving functionality, bioavailability, nutraceutical and sensory attributes of fortified foods using phenolics-loaded nanocarriers as natural ingredients","volume":"137","author":"Delfanian","year":"2020","journal-title":"Food Res. Int."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1111\/ijfs.14521","article-title":"Application of vegetable concentrates and powders in coloured pasta production","volume":"55","author":"Sobota","year":"2020","journal-title":"Int. J. Food Sci. Technol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"130141","DOI":"10.1016\/j.foodchem.2021.130141","article-title":"Valorization of natural colors as health-promoting bioactive compounds: Phytochemical profile, extraction techniques, and pharmacological perspectives","volume":"362","author":"Manzoor","year":"2021","journal-title":"Food Chem."},{"key":"ref_16","first-page":"55","article-title":"Proximate, Mineral Composition and Sensory Acceptability of Home Made Noodles from Stinging Nettle (Urtica simensis) Leaves and Wheat Flour Blends","volume":"6","author":"Alemayehu","year":"2016","journal-title":"Int. J. Food Sci. Nutr. Eng."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"108959","DOI":"10.1016\/j.lwt.2019.108959","article-title":"Effect of moisturizing pre-treatment of dietary fibre preparations on formation of gluten network during model dough mixing\u2014A study with application of FT-IR and FT-Raman spectroscopy","volume":"121","author":"Nawrocka","year":"2020","journal-title":"LWT Food Sci. Technol."},{"key":"ref_18","first-page":"152","article-title":"Zmiany zawarto\u015bci t\u0142uszczu wolnego w czasie procesu produkcji makaronu jajecznego","volume":"22","author":"Sobota","year":"2015","journal-title":"Zywn. Nauk. Technol. Jakosc\/Food. Sci. Technol. Qual."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.tifs.2021.01.078","article-title":"Update of the concept of type 5 resistant starch (RS5): Self-assembled starch V-type complexes","volume":"109","author":"Tovar","year":"2021","journal-title":"Trends Food Sci. Technol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"857120","DOI":"10.1155\/2013\/857120","article-title":"Mineral properties and dietary value of raw and processed stinging nettle (Urtica dioica L.)","volume":"2013","author":"Rutto","year":"2013","journal-title":"Int. J. Food Sci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.7251\/QOL1301026R","article-title":"Determination of protein and mineral contents in stinging nettle","volume":"7","author":"Rafajlovska","year":"2013","journal-title":"Qual. Life (Banja Luka) APEIRON"},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Paulauskien\u0117, A., Tarasevi\u010dien\u0117, \u017d., and Laukagalis, V. (2021). Influence of harvesting time on the chemical composition of wild stinging nettle (Urtica dioica L.). Plants, 10.","DOI":"10.3390\/plants10040686"},{"key":"ref_23","first-page":"8","article-title":"Highlights on nutritional and therapeutic value of stinging nettle (Urtica Dioica). Nutrition View project Quality management in hospitals","volume":"7","author":"Ait","year":"2015","journal-title":"Int. J. Pharm. Pharm. Sci."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"101743","DOI":"10.1016\/j.algal.2019.101743","article-title":"Effect of Arthrospira platensis (spirulina) incorporation on the rheological and bioactive properties of gluten-free fresh pasta","volume":"45","author":"Fradinho","year":"2020","journal-title":"Algal Res."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Kraw\u0119cka, A., Sobota, A., and Sykut-Doma\u0144ska, E. (2020). Physicochemical, Sensory, and Cooking Qualities of Pasta Enriched with Oat \u03b2-Glucans, Xanthan Gum, and Vital Gluten. Foods, 9.","DOI":"10.3390\/foods9101412"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Zarzycki, P., Sykut-Doma\u0144ska, E., Sobota, A., Teterycz, D., Kraw\u0119cka, A., Blicharz-Kania, A., Andrejko, D., and Zdybel, B. (2020). Flaxseed Enriched Pasta\u2014Chemical Composition and Cooking Quality. Foods, 9.","DOI":"10.3390\/foods9040404"},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Yu, K., Zhou, H.-M., Zhu, K.-X., Guo, X.-N., and Peng, W. (2020). Water Cooking Stability of Dried Noodles Enriched with Different Particle Size and Concentration Green Tea Powders. Foods, 9.","DOI":"10.3390\/foods9030298"},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Teterycz, D., Sobota, A., Przygodzka, D., and Lysakowska, P. (2021). Hemp seed (Cannabis sativa L.) enriched pasta: Physicochemical properties and quality evaluation. PLoS ONE, 16.","DOI":"10.1371\/journal.pone.0248790"},{"key":"ref_29","first-page":"277","article-title":"Ocena glikemii poposi\u0142kowej i indeksu glikemicznego innowacyjnych pe\u0142noziarnistych produkt\u00f3w zbo\u017cowych u zdrowych doros\u0142ych os\u00f3b","volume":"3","author":"Lange","year":"2018","journal-title":"Handel Wewn\u0119trzny"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.numecd.2017.07.005","article-title":"A systematic review on the relations between pasta consumption and cardio-metabolic risk factors","volume":"27","author":"Huang","year":"2017","journal-title":"Nutr. Metab. Cardiovasc. Dis."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1016\/j.foodchem.2017.11.027","article-title":"Inhibitory effects of edible seaweeds, polyphenolics and alginates on the activities of porcine pancreatic \u03b1-amylase","volume":"245","author":"Zaharudin","year":"2018","journal-title":"Food Chem."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.lwt.2017.09.002","article-title":"Slowing starch digestion and inhibiting digestive enzyme activity using plant flavanols\/tannins\u2014A review of efficacy and mechanisms","volume":"87","author":"Barrett","year":"2018","journal-title":"LWT Food Sci. Technol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s11130-018-0711-0","article-title":"The Antidiabetic Potential of Black Mulberry Extract-Enriched Pasta through Inhibition of Enzymes and Glycemic Index","volume":"74","author":"Yazdankhah","year":"2019","journal-title":"Plant Foods Hum. Nutr."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.foodres.2017.11.003","article-title":"Inhibitory activity of phenolic-rich pistachio green hull extract-enriched pasta on key type 2 diabetes relevant enzymes and glycemic index","volume":"105","author":"Lalegani","year":"2018","journal-title":"Food Res. Int."},{"key":"ref_35","unstructured":"AACC (2020, July 29). American Association of Cereal Chemistry Approved Methods. 10th ed. St.Paul. Available online: http:\/\/methods.aaccnet.org\/toc.aspx."},{"key":"ref_36","unstructured":"AOAC (2020, July 29). Association of Official Analytical Chemists International. Official Methods (20th ed.). Rockville. Available online: https:\/\/www.aoac.org\/official-methods-of-analysis-21st-edition-2019\/."},{"key":"ref_37","unstructured":"International Organization for Standardization ISO 6491:1998 (2020, July 29). Determination of phosphorus content. Spectrophotometric method. Available online: https:\/\/www.iso.org\/standard\/12864.html."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.foodchem.2013.10.031","article-title":"Effect of abiotic elicitation on main health-promoting compounds, antioxidant activity and commercial quality of butter lettuce (Lactuca sativa L.)","volume":"148","author":"Jakubczyk","year":"2014","journal-title":"Food Chem."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1017\/S0007114510000589","article-title":"Relative glycaemic impact of customarily consumed portions of eighty-three foods measured by digesting in vitro and adjusting for food mass and apparent glucose disposal","volume":"104","author":"Monro","year":"2010","journal-title":"Br. J. Nutr."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.lwt.2013.09.004","article-title":"Antioxidant capacity, arabinoxylans content and invitro glycaemic index of cereal-based snacks incorporated with brewer\u2019s spent grain","volume":"55","author":"Reis","year":"2014","journal-title":"LWT Food Sci. Technol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S0271-5317(97)00010-9","article-title":"A starch hydrolysis procedure to estimate glycemic index","volume":"17","year":"1997","journal-title":"Nutr. Res."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/26\/22\/6909\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:31:09Z","timestamp":1760167869000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/26\/22\/6909"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,16]]},"references-count":41,"journal-issue":{"issue":"22","published-online":{"date-parts":[[2021,11]]}},"alternative-id":["molecules26226909"],"URL":"https:\/\/doi.org\/10.3390\/molecules26226909","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,16]]}}}