{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:36:39Z","timestamp":1760236599305,"version":"build-2065373602"},"reference-count":101,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T00:00:00Z","timestamp":1638489600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003407","name":"MIUR","doi-asserted-by":"publisher","award":["PON PANDION 01_00375"],"award-info":[{"award-number":["PON PANDION 01_00375"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>In the field of optical sensors, small molecules responsive to metal cations are of current interest. Probes displaying aggregation-induced emission (AIE) can solve the problems due to the aggregation-caused quenching (ACQ) molecules, scarcely emissive as aggregates in aqueous media and in tissues. The addition of a metal cation to an AIE ligand dissolved in solution can cause a \u201cturn-on\u201d of the fluorescence emission. Half-cruciform-shaped molecules can be a winning strategy to build specific AIE probes. Herein, we report the synthesis and characterization of a novel L-shaped fluorophore containing a benzofuran core condensed with 3-hydroxy-2-naphthaldehyde crossed with a nitrobenzene moiety. The novel AIE probe produces a fast colorimetric and fluorescence response toward zinc (II) in both in neutral and basic conditions. Acting as a tridentate ligand, it produces a complex with enhanced and red-shifted emission in the DR\/NIR spectral range. The AIE nature of both compounds was examined on the basis of X-ray crystallography and DFT analysis.<\/jats:p>","DOI":"10.3390\/molecules26237347","type":"journal-article","created":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T03:10:38Z","timestamp":1638760238000},"page":"7347","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A Novel L-Shaped Fluorescent Probe for AIE Sensing of Zinc (II) Ion by a DR\/NIR Response"],"prefix":"10.3390","volume":"26","author":[{"given":"Rosita","family":"Diana","sequence":"first","affiliation":[{"name":"Department of Agriculture, University of Napoli Federico II, 80055 Portici, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0572-5436","authenticated-orcid":false,"given":"Ugo","family":"Caruso","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, University of Napoli Federico II, 80126 Napoli, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2853-5643","authenticated-orcid":false,"given":"Francesco Silvio","family":"Gentile","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, University of Napoli Federico II, 80126 Napoli, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4795-2573","authenticated-orcid":false,"given":"Luigi","family":"Di Costanzo","sequence":"additional","affiliation":[{"name":"Department of Agriculture, University of Napoli Federico II, 80055 Portici, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9253-0794","authenticated-orcid":false,"given":"Barbara","family":"Panunzi","sequence":"additional","affiliation":[{"name":"Department of Agriculture, University of Napoli Federico II, 80055 Portici, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1039\/C3CS60271K","article-title":"Recent progress in the development of near-infrared fluorescent probes for bioimaging applications","volume":"43","author":"Guo","year":"2014","journal-title":"Chem. Soc. Rev."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.chempr.2017.05.010","article-title":"AIE Luminogens for Bioimaging and Theranostics: From Organelles to Animals","volume":"3","author":"Qian","year":"2017","journal-title":"Chem"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1605497","DOI":"10.1002\/adma.201605497","article-title":"Rational Design of Molecular Fluorophores for Biological Imaging in the NIR-II Window","volume":"29","author":"Yang","year":"2017","journal-title":"Adv. Mater."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1080\/00268977000100171","article-title":"The energy gap law for radiationless transitions in large molecules","volume":"18","author":"Englman","year":"1970","journal-title":"J. Mol. Phys."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"7289","DOI":"10.1021\/j100081a010","article-title":"Energy gap law for nonradiative and radiative charge transfer in isolated and in solvated supermolecules","volume":"98","author":"Bixon","year":"1994","journal-title":"J. Phys. Chem."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"213693","DOI":"10.1016\/j.ccr.2020.213693","article-title":"AIE-based luminescence probes for metal ion detection","volume":"429","author":"Alam","year":"2021","journal-title":"Coord. Chem. Rev."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1021\/acschembio.8b00014","article-title":"Fluorescent Chemosensors as Future Tools for Cancer Biology","volume":"13","author":"Singh","year":"2018","journal-title":"ACS Chem. Biol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"6449","DOI":"10.1039\/C6CS00413J","article-title":"Fluorescent chemosensors manipulated by dual\/triple interplaying sensing mechanisms","volume":"45","author":"He","year":"2016","journal-title":"Chem. Soc. Rev."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Hong, Y., Lam, J.W.Y., and Tang, B.Z. (2009). Aggregation-induced emission: Phenomenon, mechanism and applications. Chem. Commun., 4332\u20134353.","DOI":"10.1039\/b904665h"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"7817","DOI":"10.1021\/jp101568f","article-title":"Theory of excited state decays and optical spectra: Application to polyatomic molecules","volume":"114","author":"Niu","year":"2010","journal-title":"J. Phys. Chem. A"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.chemphys.2010.03.004","article-title":"Vibration correlation function formalism of radiative and non-radiative rates for complex molecules","volume":"370","author":"Peng","year":"2010","journal-title":"Chem. Phys."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.physrep.2013.12.002","article-title":"Excited states structure and processes: Understanding organic light-emitting diodes at the molecular level","volume":"537","author":"Shuai","year":"2014","journal-title":"Phys. Rep."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"7258","DOI":"10.1039\/C7SC03076B","article-title":"2,5-bis(4-alkoxycarbonylphenyl)-1,4-diaryl-1,4-dihydropyrrolo[3,2-b]pyrrole (AAPP) AIEgens: Tunable RIR and TICT characteristics and their multifunctional applications","volume":"8","author":"Li","year":"2017","journal-title":"Chem. Sci."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.aca.2018.01.056","article-title":"An active fluorescent probe based on aggregation-induced emission for intracellular bioimaging of Zn2+ and tracking of interactions with single-stranded DNA","volume":"1013","author":"Wen","year":"2018","journal-title":"Anal. Chim. Acta"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"10721","DOI":"10.1021\/acs.iecr.0c01869","article-title":"Advanced Properties and Applications of AIEgens-Inspired Smart Materials","volume":"59","author":"Roy","year":"2020","journal-title":"Ind. Eng. Chem. Res."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"9888","DOI":"10.1002\/anie.201916729","article-title":"Aggregation-Induced Emission: New Vistas at the Aggregate Level","volume":"59","author":"Zhao","year":"2020","journal-title":"Angew. Chem.-Int. Ed."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"100317","DOI":"10.1016\/j.jphotochemrev.2019.100317","article-title":"\u201cAggregation-induced emission\u201d of transition metal compounds: Design, mechanistic insights, and applications","volume":"41","author":"Alam","year":"2019","journal-title":"J. Photochem. Photobiol. C Photochem. Rev."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1002\/cphc.201900113","article-title":"Aggregation-Induced Emission-Based Sensing Platform for Selective Detection of Zn2+: Experimental and Theoretical Investigations","volume":"20","author":"Naskar","year":"2019","journal-title":"ChemPhysChem"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1002\/ejic.201600005","article-title":"Aggregation-Induced Phosphorescent Emission from ReI Complexes: Synthesis and Property Studies","volume":"2016","author":"Chen","year":"2016","journal-title":"Eur. J. Inorg. Chem."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s40242-021-0331-3","article-title":"AIE Ligand Constructed Zn(II) Complex with Reversible Photo-induced Color and Emission Changes","volume":"37","author":"Qin","year":"2021","journal-title":"Chem. Res. Chin. Univ."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"4073","DOI":"10.1039\/D1QM00078K","article-title":"AIE polymers in sensing, imaging and theranostic applications","volume":"5","author":"Hu","year":"2021","journal-title":"Mater. Chem. Front."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"4485","DOI":"10.1039\/C6SC01254J","article-title":"An arch-bridge-type fluorophore for bridging the gap between aggregation-caused quenching (ACQ) and aggregation-induced emission (AIE)","volume":"7","author":"Huang","year":"2016","journal-title":"Chem. Sci."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Caruso, U., Panunzi, B., Diana, R., Concilio, S., Sessa, L., Shikler, R., Nabha, S., Tuzi, A., and Piotto, S. (2018). AIE\/ACQ effects in two DR\/NIR emitters: A structural and DFT comparative analysis. Molecules, 23.","DOI":"10.3390\/molecules23081947"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"3212","DOI":"10.1021\/ol501226x","article-title":"Acid-responsive fluorescent compounds based on nitro-group-substituted L-shaped pentacycles, pyrrolo[1,2-a][1,8]naphthylidines","volume":"16","author":"Tateno","year":"2014","journal-title":"Org. Lett."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Diana, R., Caruso, U., Di Costanzo, L., Bakayoko, G., and Panunzi, B. (2020). A novel DR\/NIR T-shaped aiegen: Synthesis and x-ray crystal structure study. Crystals, 10.","DOI":"10.3390\/cryst10040269"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.dyepig.2013.09.037","article-title":"Fluorescence response of pyridinyl- and\/or dibutylaniline-Capped 2,6,9,10-Tetravinylanthracenes to metal ions","volume":"101","author":"Zheng","year":"2014","journal-title":"Dye. Pigment."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.snb.2012.11.066","article-title":"Multisignaling metal sensor: Optical, electrochemical, and electrochemiluminescent responses of cruciform-shaped alkynylpyrene for selective recognition of Fe3+","volume":"177","author":"Oh","year":"2013","journal-title":"Sens. Actuators B Chem."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"9346","DOI":"10.1039\/C7NJ01531C","article-title":"T-Shaped donor-acceptor-donor type tetraphenylethylene substituted quinoxaline derivatives: Aggregation-induced emission and mechanochromism","volume":"41","author":"Ekbote","year":"2017","journal-title":"New J. Chem."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"3899","DOI":"10.1021\/cr940745l","article-title":"Structural Changes Accompanying Intramolecular Electron Transfer: Focus on Twisted Intramolecular Charge-Transfer States and Structures","volume":"103","author":"Grabowski","year":"2003","journal-title":"Chem. Rev."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"11581","DOI":"10.1002\/chem.200900656","article-title":"Controlling the conformational changes in donor-acceptor [4]dendralenes through intramolecular charge-transfer processes","volume":"15","author":"Kanibolotsky","year":"2009","journal-title":"Chem. -A Eur. J."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"4228","DOI":"10.1039\/C4CS00325J","article-title":"Biosensing by luminogens with aggregation-induced emission characteristics","volume":"44","author":"Kwok","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Panunzi, B., Diana, R., and Caruso, U. (2019). A highly efficient white luminescent zinc (II) based metallopolymer by RGB approach. Polymers, 11.","DOI":"10.3390\/polym11101712"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1016\/j.ccr.2006.03.007","article-title":"Photophysics in bipyridyl and terpyridyl platinum(II) acetylides","volume":"250","author":"Castellano","year":"2006","journal-title":"Coord. Chem. Rev."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.inoche.2012.11.037","article-title":"Fluorescent metallopolymers with Zn(II) in a Schiff base\/phenoxide coordination environment","volume":"29","author":"Caruso","year":"2013","journal-title":"Inorg. Chem. Commun."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"4304","DOI":"10.1021\/ja003693s","article-title":"Highly phosphorescent bis-cyclometalated iridium complexes: Synthesis, photophysical characterization, and use in organic light emitting diodes","volume":"123","author":"Lamansky","year":"2001","journal-title":"J. Am. Chem. Soc."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1002\/macp.201500120","article-title":"High solid state photoluminescence quantum yields and effective color tuning in polyvinylpyridine based zinc(II) metallopolymers","volume":"216","author":"Borbone","year":"2015","journal-title":"Macromol. Chem. Phys."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"7061","DOI":"10.1039\/c2cs35171d","article-title":"Photofunctional triplet excited states of cyclometalated Ir(iii) complexes: Beyond electroluminescence","volume":"41","author":"You","year":"2012","journal-title":"Chem. Soc. Rev."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.inoche.2010.09.027","article-title":"Two aminobenzothiazole derivatives for Pd(II) and Zn(II) coordination: Synthesis, characterization and solid state fluorescence","volume":"14","author":"Caruso","year":"2011","journal-title":"Inorg. Chem. Commun."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Diana, R., and Panunzi, B. (2021). Zinc (Ii) and aiegens: The \u201cclip approach\u201d for a novel fluorophore family. A review. Molecules, 26.","DOI":"10.3390\/molecules26144176"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"11718","DOI":"10.1021\/acs.chemrev.5b00263","article-title":"Aggregation-Induced Emission: Together We Shine, United We Soar!","volume":"115","author":"Mei","year":"2015","journal-title":"Chem. Rev."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1021\/acsanm.8b00226","article-title":"Multifunctional Metallo-Organic Vesicles Displaying Aggregation-Induced Emission: Two-Photon Cell-Imaging, Drug Delivery, and Specific Detection of Zinc Ion","volume":"1","author":"Wei","year":"2018","journal-title":"ACS Appl. Nano Mater."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Diana, R., and Panunzi, B. (2020). The role of zinc(II) ion in fluorescence tuning of tridentate pincers: A review. Molecules, 25.","DOI":"10.3390\/molecules25214984"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"15349","DOI":"10.1002\/chem.201403811","article-title":"Restriction of intramolecular motions: The general mechanism behind aggregation-induced emission","volume":"20","author":"Leung","year":"2014","journal-title":"Chem. -A Eur. J."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.inoche.2019.04.007","article-title":"Highly efficient dicyano-phenylenevinylene fluorophore as polymer dopant or zinc-driven self-assembling building block","volume":"104","author":"Diana","year":"2019","journal-title":"Inorg. Chem. Commun."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1901520","DOI":"10.1002\/adom.201901520","article-title":"Exploration of High Efficiency AIE-Active Deep\/Near-Infrared Red Emitters in OLEDs with High-Radiance","volume":"8","author":"Wan","year":"2020","journal-title":"Adv. Opt. Mater."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.optmat.2017.03.018","article-title":"A morphology and size-dependent ON-OFF switchable NIR-emitting naphthothiazolium cyanine dye: AIE-active CIEE effect","volume":"66","author":"Yang","year":"2017","journal-title":"Opt. Mater."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.ijbiomac.2018.09.153","article-title":"Evaluating the biological properties of synthetic 4-nitrophenyl functionalized benzofuran derivatives with telomeric DNA binding and antiproliferative activities","volume":"121","author":"Carella","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/j.crci.2008.05.015","article-title":"Synthesis, structure and reactivity of amino-benzodifurane derivatives","volume":"12","author":"Caruso","year":"2009","journal-title":"Comptes Rendus Chim."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Caruso, U., Diana, R., Tuzi, A., and Panunzi, B. (2020). Novel solid-state emissive polymers and polymeric blends from a T-Shaped benzodifuran scaffold: A comparative study. Polymers, 12.","DOI":"10.3390\/polym12030718"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.inoche.2019.04.016","article-title":"A symmetrical azo-based fluorophore and the derived salen multipurpose framework for emissive layers","volume":"104","author":"Diana","year":"2019","journal-title":"Inorg. Chem. Commun."},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Reshma, R., Selwin Joseyphus, R., Arish, D., Reshmi Jaya, R.J., and Johnson, J. (2021). Tridentate imidazole-based Schiff base metal complexes: Molecular docking, structural and biological studies. J. Biomol. Struct. Dyn.","DOI":"10.1080\/07391102.2021.1914171"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"127682","DOI":"10.1016\/j.molstruc.2020.127682","article-title":"Structural, spectral and biological investigations on Cu(II) and Zn(II) complexes derived from NNO donor tridentate Schiff base: Crystal structure of a 1D Cu(II) coordination polymer","volume":"1206","author":"Jayendran","year":"2020","journal-title":"J. Mol. Struct."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1002\/ejic.201400095","article-title":"Series of O,N,O-tridentate ligands zinc(II) complexes with high solid-state photoluminescence quantum yield","volume":"16","author":"Borbone","year":"2014","journal-title":"Eur. J. Inorg. Chem."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1107\/S0907444909047374","article-title":"Integration, scaling, space-group assignment and post-refinement","volume":"66","author":"Kabsch","year":"2010","journal-title":"Acta Crystallogr. Sect. D Biol. Crystallogr."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1107\/S1600576715016970","article-title":"Solving proteins at non-atomic resolution by direct methods","volume":"48","author":"Burla","year":"2015","journal-title":"J. Appl. Crystallogr."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1107\/S0108767307043930","article-title":"A short history of SHELX","volume":"64","author":"Sheldrick","year":"2008","journal-title":"Acta Crystallogr. Sect. A Found. Crystallogr."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1107\/S0021889812029111","article-title":"WinGX and ORTEP for Windows: An update","volume":"45","author":"Farrugia","year":"2012","journal-title":"J. Appl. Crystallogr."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1107\/S1600576719014092","article-title":"Mercury 4.0: From visualization to analysis, design and prediction","volume":"53","author":"MacRae","year":"2020","journal-title":"J. Appl. Crystallogr."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"204111","DOI":"10.1063\/5.0004892","article-title":"The CRYSTAL code, 1976-2020 and beyond, a long story","volume":"152","author":"Dovesi","year":"2020","journal-title":"J. Chem. Phys."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"5648","DOI":"10.1063\/1.464913","article-title":"Density-functional thermochemistry. III. The role of exact exchange","volume":"98","author":"Becke","year":"1993","journal-title":"J. Chem. Phys."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1103\/PhysRevB.37.785","article-title":"Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density","volume":"37","author":"Lee","year":"1988","journal-title":"Phys. Rev. B"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"154104","DOI":"10.1063\/1.3382344","article-title":"A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu","volume":"132","author":"Grimme","year":"2010","journal-title":"J. Chem. Phys."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"2364","DOI":"10.1002\/jcc.26013","article-title":"BSSE-correction scheme for consistent gaussian basis sets of double- and triple-zeta valence with polarization quality for solid-state calculations","volume":"40","author":"Laun","year":"2019","journal-title":"J. Comput. Chem."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"3297","DOI":"10.1039\/b508541a","article-title":"Balanced basis sets of split valence, triple zeta valence and quadruple zeta valence quality for H to Rn: Design and assessment of accuracy","volume":"7","author":"Weigend","year":"2005","journal-title":"Phys. Chem. Chem. Phys."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"10796","DOI":"10.1039\/D0TA01760D","article-title":"Metal defects in HKUST-1 MOF revealed by vibrational spectroscopy: A combined quantum mechanical and experimental study","volume":"8","author":"Gentile","year":"2020","journal-title":"J. Mater. Chem. A"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"4450","DOI":"10.1039\/c2dt32427j","article-title":"Aggregates of a triphenylene based chemosensing ensemble for sensitive detection of cyanide ions in an aqueous medium","volume":"42","author":"Bhalla","year":"2013","journal-title":"Dalton Trans."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"15195","DOI":"10.1039\/D0NJ02687E","article-title":"A selective purine-based fluorescent chemosensor for the \u201cnaked-eye\u201d detection of zinc ions (Zn2+): Applications in live cell imaging and test strips","volume":"44","author":"Xu","year":"2020","journal-title":"New J. Chem."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1021\/acs.iecr.7b03826","article-title":"Fluorescent Sensor for Sequentially Monitoring Zinc(II) and Cyanide Anion in Near-Perfect Aqueous Media","volume":"57","author":"Jang","year":"2018","journal-title":"Ind. Eng. Chem. Res."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.dyepig.2012.09.020","article-title":"A novel class of Zn(II) Schiff base complexes with aggregation-induced emission enhancement (AIEE) properties: Synthesis, characterization and photophysical\/electrochemical properties","volume":"96","author":"Xie","year":"2013","journal-title":"Dye. Pigment."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.jcis.2017.11.034","article-title":"A new three-dimensional zinc-based metal-organic framework as a fluorescent sensor for detection of cadmium ion and nitrobenzene","volume":"513","author":"Pan","year":"2018","journal-title":"J. Colloid Interface Sci."},{"key":"ref_71","doi-asserted-by":"crossref","unstructured":"Diana, R., Panunzi, B., Tuzi, A., Piotto, S., Concilio, S., and Caruso, U. (2019). An amphiphilic pyridinoyl-hydrazone probe for colorimetric and fluorescence pH sensing. Molecules, 24.","DOI":"10.3390\/molecules24213833"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.inoche.2014.05.009","article-title":"Bulky group functionalized porphyrin and its Zn (II) complex with high emission in aggregation","volume":"46","author":"Zhang","year":"2014","journal-title":"Inorg. Chem. Commun."},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Diana, R., Panunzi, B., Concilio, S., Marrafino, F., Shikler, R., Caruso, T., and Caruso, U. (2019). The effect of bulky substituents on two \u03c0-conjugated mesogenic fluorophores. Their organic polymers and zinc-bridged luminescent networks. Polymers, 11.","DOI":"10.3390\/polym11091379"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"26477","DOI":"10.1038\/srep26477","article-title":"Nanomolar pyrophosphate detection and nucleus staining in living cells with simple terpyridine-Zn(II) complexes","volume":"6","author":"Chao","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.molstruc.2019.07.098","article-title":"Two tridentate pyridinyl-hydrazone zinc(II) complexes as fluorophores for blue emitting layers","volume":"1197","author":"Diana","year":"2019","journal-title":"J. Mol. Struct."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1080\/10610278.2019.1659266","article-title":"Self-assembly of emissive metallocycles with tetraphenylethylene, BODIPY and terpyridine in one system","volume":"31","author":"Yan","year":"2019","journal-title":"Supramol. Chem."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"2842","DOI":"10.1039\/C7SC05442D","article-title":"Isotopic graphene-isolated-Au-nanocrystals with cellular Raman-silent signals for cancer cell pattern recognition","volume":"9","author":"Zou","year":"2018","journal-title":"Chem. Sci."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"20488","DOI":"10.1039\/C7RA01135K","article-title":"Red-shift in fluorescence emission of D-A type asymmetrical Zn(II) complexes by extending the \u03c0-\u03c0 stacking interaction","volume":"7","author":"Wang","year":"2017","journal-title":"RSC Adv."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"2100174","DOI":"10.1002\/marc.202100174","article-title":"Significantly Red-Shifted Emissions of Nonconventional AIE Polymers Containing Zwitterionic Components","volume":"42","author":"Huang","year":"2021","journal-title":"Macromol. Rapid Commun."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.1039\/C5TC03369A","article-title":"Long wavelength AIEgen of quinoline-malononitrile","volume":"4","author":"Guo","year":"2016","journal-title":"J. Mater. Chem. C"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.snb.2015.10.110","article-title":"A ratiometric fluorescent chemosensor for Zn2+ in aqueous solution through an ESIPT coupled AIE process","volume":"224","author":"Qin","year":"2016","journal-title":"Sens. Actuators B Chem."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"3305","DOI":"10.1016\/j.tet.2017.04.039","article-title":"A novel \u201cturn-on\u201d dipyrrin-type fluorescent detector of Zn2+ based on tetraphenylethene","volume":"73","author":"Dong","year":"2017","journal-title":"Tetrahedron"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.jlumin.2017.10.064","article-title":"Highly selective turn-on fluorogenic chemosensor for Zn(II) detection based on aggregation-induced emission","volume":"194","author":"Wen","year":"2018","journal-title":"J. Lumin."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.dyepig.2017.12.025","article-title":"Tailoring the sensing behaviors to Zn2+ and AIEE properties of phenanthroline derivatives through isomer engineering","volume":"150","author":"Liang","year":"2018","journal-title":"Dye. Pigment."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"11080","DOI":"10.1039\/c1cc13790e","article-title":"A new ligand and its complex with multi-stimuli-responsive and aggregation-induced emission effects","volume":"47","author":"Xu","year":"2011","journal-title":"Chem. Commun."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1039\/C8TC05526B","article-title":"Two spirobifluorene-based fluorescent probes with aggregation-induced emission properties: Synthesis and application in the detection of Zn2+ and cell imaging","volume":"7","author":"Wan","year":"2019","journal-title":"J. Mater. Chem. C"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"14039","DOI":"10.1039\/C6DT02657E","article-title":"A selective fluorescent sensor for Zn2+ based on aggregation-induced emission (AIE) activity and metal chelating ability of bis(2-pyridyl)diphenylethylene","volume":"45","author":"Gabr","year":"2016","journal-title":"Dalton Trans."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"4806","DOI":"10.1039\/C6NJ03953G","article-title":"Hexaphenylbenzene-based fluorescent aggregates for detection of zinc and pyrophosphate ions in aqueous media: Tunable self-assembly behaviour and construction of a logic device","volume":"41","author":"Pramanik","year":"2017","journal-title":"New J. Chem."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1021\/acsomega.6b00564","article-title":"Zinc(II)-Tetradentate-Coordinated Probe with Aggregation-Induced Emission Characteristics for Selective Imaging and Photoinactivation of Bacteria","volume":"2","author":"Feng","year":"2017","journal-title":"ACS Omega"},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1016\/j.tetlet.2010.02.009","article-title":"A new fluorescent sensor for the detection of pyrophosphate based on a tetraphenylethylene moiety","volume":"51","author":"Park","year":"2010","journal-title":"Tetrahedron Lett."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1246\/cl.200001","article-title":"A New Thiophene-based Aggregation-induced Emission Chemosensor for Selective Detection of Zn2+ Ions and Its Turn off","volume":"49","author":"Musib","year":"2020","journal-title":"Chem. Lett."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"12019","DOI":"10.1039\/D0NJ02236E","article-title":"Thieno[3,2-c]pyran: An ESIPT based fluorescence \u201cturn-on\u201d molecular chemosensor with AIE properties for the selective recognition of Zn2+ ion","volume":"44","author":"Singhal","year":"2020","journal-title":"New J. Chem."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"9651","DOI":"10.1039\/C7TC03046K","article-title":"Synthesis of an aggregation-induced emission (AIE) active salicylaldehyde based Schiff base: Study of mechanoluminescence and sensitive Zn(ii) sensing","volume":"5","author":"Pasha","year":"2017","journal-title":"J. Mater. Chem. C"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jphotochem.2014.12.013","article-title":"A tetraphenylethylene-based \u201cturn on\u201d fluorescent sensor for the rapid detection of Ag+ ions with high selectivity","volume":"301","author":"Li","year":"2015","journal-title":"J. Photochem. Photobiol. A Chem."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"5750","DOI":"10.1002\/anie.201801653","article-title":"Fluorogenic Ag+\u2013Tetrazolate Aggregation Enables Efficient Fluorescent Biological Silver Staining","volume":"57","author":"Xie","year":"2018","journal-title":"Angew. Chem.-Int. Ed."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1039\/C9DT03985F","article-title":"Turn-on fluorescence in a pyridine-decorated tetraphenylethylene: The cooperative effect of coordination-driven rigidification and silver ion induced aggregation","volume":"49","author":"Wang","year":"2020","journal-title":"Dalton Trans."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ica.2017.01.002","article-title":"From cadmium(II)-aroylhydrazone complexes to metallopolymers with enhanced photoluminescence. A structural and DFT study","volume":"458","author":"Borbone","year":"2017","journal-title":"Inorganica Chimica Acta"},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jlumin.2019.04.052","article-title":"Fluorescence pH-dependent sensing of Zn(II)by a tripodal ligand. A comparative X-ray and DFT study","volume":"212","author":"Panunzi","year":"2019","journal-title":"J. Lumin."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1021\/ac504153c","article-title":"Fluorescence Turn-On Chemosensor for Highly Selective and Sensitive Detection and Bioimaging of Al3+ in Living Cells Based on Ion-Induced Aggregation","volume":"87","author":"Gui","year":"2015","journal-title":"Anal. Chem."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.dyepig.2018.03.055","article-title":"A real-time tripodal colorimetric\/fluorescence sensor for multiple target metal ions","volume":"155","author":"Diana","year":"2018","journal-title":"Dye. Pigment."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1021\/acssensors.6b00289","article-title":"Highly Selective Turn-On Fluorogenic Chemosensor for Robust Quantification of Zn(II) Based on Aggregation Induced Emission Enhancement Feature","volume":"1","author":"Shyamal","year":"2016","journal-title":"ACS Sens."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/26\/23\/7347\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:39:32Z","timestamp":1760168372000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/26\/23\/7347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,3]]},"references-count":101,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2021,12]]}},"alternative-id":["molecules26237347"],"URL":"https:\/\/doi.org\/10.3390\/molecules26237347","relation":{},"ISSN":["1420-3049"],"issn-type":[{"type":"electronic","value":"1420-3049"}],"subject":[],"published":{"date-parts":[[2021,12,3]]}}}