{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T19:38:19Z","timestamp":1781638699406,"version":"3.54.5"},"reference-count":90,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,4,12]],"date-time":"2022-04-12T00:00:00Z","timestamp":1649721600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>The fruit and leaves of Eugenia dysenterica DC., locally known as cagaita, are rich in antioxidant glycosylated quercetin derivatives and phenolic compounds that have beneficial effects on diabetes mellitus, hypertension and general inflammation. We conducted a literature search to investigate the nutraceutical potentials of these phenolic compounds for treating obesity, diabetes mellitus and intestinal inflammatory disease. The phenolic compounds in E. dysenterica have demonstrated effects on carbohydrate metabolism, which can prevent the development of these chronic diseases and reduce LDL (low-density lipoprotein) cholesterol and hypertension. E. dysenterica also improves intestinal motility and microbiota and protects gastric mucosa, thereby preventing inflammation. However, studies are necessary to identify the mechanism by which E. dysenterica nutraceutical compounds act on such pathological processes to support future research.<\/jats:p>","DOI":"10.3390\/molecules27082477","type":"journal-article","created":{"date-parts":[[2022,4,12]],"date-time":"2022-04-12T22:48:45Z","timestamp":1649803725000},"page":"2477","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Nutraceutic Potential of Bioactive Compounds of Eugenia dysenterica DC in Metabolic Alterations"],"prefix":"10.3390","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9171-4698","authenticated-orcid":false,"given":"Lidiani Figueiredo","family":"Santana","sequence":"first","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul\u2014UFMS, Campo Grande 79070-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3010-9715","authenticated-orcid":false,"given":"Sandramara","family":"Sasso","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul\u2014UFMS, Campo Grande 79070-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana Figueiredo Santana","family":"Aquino","sequence":"additional","affiliation":[{"name":"Higher Level Technician, Personnel Development Division, State University of Mato Grosso do Sul\u2014UEMS, Dourados 79804-970, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karine","family":"de C\u00e1ssia Freitas","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul\u2014UFMS, Campo Grande 79070-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"de C\u00e1ssia Avellaneda Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul\u2014UFMS, Campo Grande 79070-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8599-9276","authenticated-orcid":false,"given":"Arnildo","family":"Pott","sequence":"additional","affiliation":[{"name":"Institute of Biosciences, Federal University of Mato Grosso do Sul\u2014UFMS, Campo Grande 79079-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9020-8002","authenticated-orcid":false,"given":"Valter Arag\u00e3o","family":"do Nascimento","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul\u2014UFMS, Campo Grande 79070-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Bogo","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul\u2014UFMS, Campo Grande 79070-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia","family":"de Oliveira Figueiredo","sequence":"additional","affiliation":[{"name":"Laboratory Pronabio (Bioactive Natural Products)-Chemistry Institute, Federal University of Mato Grosso do Sul\u2014UFMS, Campo Grande 79074-460, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1115-4083","authenticated-orcid":false,"given":"Priscila Aiko","family":"Hiane","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul\u2014UFMS, Campo Grande 79070-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.foodchem.2017.06.118","article-title":"Nutritional and Bioactive Potential of Myrtaceae Fruits during Ripening","volume":"239","author":"Seraglio","year":"2018","journal-title":"Food Chem."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1590\/S0102-695X2006000500006","article-title":"Estudo Fitoqu\u00edmico e Avalia\u00e7\u00e3o das Atividades Moluscicida e Larvicida dos Extratos da Casca do Caule e Folha de Eugenia Malaccensis L. 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