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Therefore, new antiviral drugs urgently need to be found to solve this problem. However, drug research and development is a very difficult task, and finding new antiviral compounds is desirable. A range of medicinal fungi such as Ganoderma lucidum and Cordyceps sinensis are widely used all over the world, and they can enhance human immunity and direct anti-virus activities and other aspects to play an antiviral role. Medicinal fungi are used as foods or as food supplements. In this review, the species of medicinal fungi with antiviral activity in recent decades and the mechanism of antiviral components were reviewed from the perspectives of human, animal, and plant viruses to provide a comprehensive theory based on better clinical utilization of medicinal fungi as antiviral agents.<\/jats:p>","DOI":"10.3390\/molecules27144457","type":"journal-article","created":{"date-parts":[[2022,7,12]],"date-time":"2022-07-12T20:52:41Z","timestamp":1657659161000},"page":"4457","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Medicinal Fungi with Antiviral Effect"],"prefix":"10.3390","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7837-8076","authenticated-orcid":false,"given":"Yu","family":"Zhang","sequence":"first","affiliation":[{"name":"School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoying","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6788-8919","authenticated-orcid":false,"given":"Jianya","family":"Ling","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China"},{"name":"State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/1469-0691.12536","article-title":"The rediscovery of smallpox","volume":"20","author":"Theves","year":"2014","journal-title":"Clin. Microbiol. Infect."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"182","DOI":"10.4161\/rna.8.2.15663","article-title":"RNA virus replication, transcription and recombination","volume":"8","author":"White","year":"2011","journal-title":"RNA Biol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.iac.2014.04.011","article-title":"Antiviral drug allergy","volume":"34","author":"Moran","year":"2014","journal-title":"Immunol. Allergy Clin. N. Am."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1053\/j.ajkd.2005.02.010","article-title":"Antiviral drug-induced nephrotoxicity","volume":"45","author":"Izzedine","year":"2005","journal-title":"Am. J. Kidney Dis."},{"key":"ref_5","first-page":"2126","article-title":"Ganoderma Lucidum Improves Physical Fitness in Women with Fibromyalgia","volume":"32","author":"Pazzi","year":"2015","journal-title":"Nutr. Hosp."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"717","DOI":"10.2174\/138920109789978757","article-title":"Ganoderma lucidum: A Potent Pharmacological Macrofungus","volume":"10","author":"Sanodiya","year":"2009","journal-title":"Curr. Pharm. Biotechnol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1016\/j.ijbiomac.2021.05.139","article-title":"Classification, structure and mechanism of antiviral polysaccharides derived from edible and medicinal fungus","volume":"183","author":"Guo","year":"2021","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Venturella, G., Ferraro, V., Cirlincione, F., and Gargano, M.L. (2021). Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22020634"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1615\/IntJMedMushrooms.2020037460","article-title":"Medicinal Mushrooms against Influenza Viruses","volume":"23","author":"Teplyakova","year":"2021","journal-title":"Int. J. Med. Mushrooms"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1615\/IntJMedMushrooms.v19.i4.10","article-title":"Medicinal Mushrooms in Human Clinical Studies. Part, I. Anticancer, Oncoimmunological, and Immunomodulatory Activities: A Review","volume":"19","author":"Wasser","year":"2017","journal-title":"Int. J. Med. Mushrooms"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.foodchem.2017.09.149","article-title":"Anti-inflammatory properties of edible mushrooms: A review","volume":"243","author":"Muszynska","year":"2018","journal-title":"Food Chem."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e2021579118","DOI":"10.1073\/pnas.2021579118","article-title":"Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection","volume":"118","author":"Jan","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1615\/IntJMedMushrooms.2021038285","article-title":"Rationalization of Mushroom-Based Preventive and Therapeutic Approaches to COVID-19: Review","volume":"23","author":"Rahman","year":"2021","journal-title":"Int. J. Med. Mushrooms"},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Senthil Kumar, K.J., Gokila Vani, M., Hsieh, H.W., Lin, C.C., and Wang, S.Y. (2021). Antcins from Antrodia cinnamomea and Antrodia salmonea Inhibit Angiotensin-Converting Enzyme 2 (ACE2) in Epithelial Cells: Can Be Potential Candidates for the Development of SARS-CoV-2 Prophylactic Agents. Plants, 10.","DOI":"10.3390\/plants10081736"},{"key":"ref_15","first-page":"172","article-title":"Possible therapeutic role of a highly standardized mixture of active compounds derived from cultured Lentinula edodes mycelia (AHCC) in patients infected with 2019 novel coronavirus","volume":"66","author":"Bertuccioli","year":"2020","journal-title":"Minerva Gastroenterol. Dietol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"139330","DOI":"10.1016\/j.scitotenv.2020.139330","article-title":"beta-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective effects\u2014Implications for coronavirus disease (COVID-19) immunotherapies","volume":"732","author":"Murphy","year":"2020","journal-title":"Sci. Total Environ."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"3745","DOI":"10.1080\/07391102.2020.1850352","article-title":"Cordycepin: A bioactive metabolite of Cordyceps militaris and polyadenylation inhibitor with therapeutic potential against COVID-19","volume":"40","author":"Verma","year":"2020","journal-title":"J. Biomol. Struct. Dyn."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1142\/S0192415X08006508","article-title":"Inhibitory Effect of TNF-alpha Produced by Macrophages Stimulated with Grifola frondosa Extract (ME) on the Growth of Influenza A\/Aichi\/2\/68 Virus in MDCK Cells","volume":"36","author":"Obi","year":"2008","journal-title":"Am. J. Chin. Med."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"117","DOI":"10.5941\/MYCO.2016.44.2.117","article-title":"Neuraminidase Inhibitors from the Fruiting Body of Phellinus igniarius","volume":"44","author":"Kim","year":"2016","journal-title":"Mycobiology"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1007\/s12275-013-3384-2","article-title":"The anti-influenza virus effect of Phellinus igniarius extract","volume":"51","author":"Lee","year":"2013","journal-title":"J. Microbiol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.3389\/fmicb.2018.01164","article-title":"Inhibition of Influenza Virus Infection by Lentinus edodes Mycelia Extract Through Its Direct Action and Immunopotentiating Activity","volume":"9","author":"Kuroki","year":"2018","journal-title":"Front. Microbiol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.antiviral.2017.02.010","article-title":"Cryptoporic acid E from Cryptoporus volvatus inhibits influenza virus replication in vitro","volume":"143","author":"Gao","year":"2017","journal-title":"Antivir. Res."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Gao, L., Sun, Y., Si, J., Liu, J., Sun, G., Sun, X., and Cao, L. (2014). Cryptoporus volvatus extract inhibits influenza virus replication in vitro and in vivo. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0113604"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"10194","DOI":"10.1021\/jf0721287","article-title":"In vivo anti-influenza virus activity of an immunomodulatory acidic polysaccharide isolated from Cordyceps militaris grown on germinated soybeans","volume":"55","author":"Ohta","year":"2007","journal-title":"J. Agric. Food Chem."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1007\/s12275-014-4300-0","article-title":"Anti-influenza effect of Cordyceps militaris through immunomodulation in a DBA\/2 mouse model","volume":"52","author":"Lee","year":"2014","journal-title":"J. Microbiol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1007\/s12250-014-3486-y","article-title":"Antiviral activity of Basidiomycete mycelia against influenza type A (serotype H1N1) and herpes simplex virus type 2 in cell culture","volume":"29","author":"Krupodorova","year":"2014","journal-title":"Virol. Sin."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1021\/acsomega.0c05264","article-title":"Novel Fatty Acid in Cordyceps Suppresses Influenza A (H1N1) Virus-Induced Proinflammatory Response Through Regulating Innate Signaling Pathways","volume":"6","author":"Li","year":"2021","journal-title":"ACS Omega"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.ijbiomac.2016.05.046","article-title":"Effect of a polysaccharide from Poria cocos on humoral response in mice immunized by H1N1 influenza and HBsAg vaccines","volume":"91","author":"Wu","year":"2016","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"110049","DOI":"10.1016\/j.biopha.2020.110049","article-title":"Mixed polysaccharides derived from Shiitake mushroom, Poriacocos, Ginger, and Tangerine peel enhanced protective immune responses in mice induced by inactivated influenza vaccine","volume":"126","author":"Zhu","year":"2020","journal-title":"Biomed. Pharm."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.carbpol.2015.12.005","article-title":"Structural characterization and antiviral activity of a novel heteropolysaccharide isolated from Grifola frondosa against enterovirus 71","volume":"144","author":"Zhao","year":"2016","journal-title":"Carbohydr. Polym."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"561758","DOI":"10.3389\/fimmu.2020.561758","article-title":"A Polysaccharide Purified from Ganoderma lucidum Acts as a Potent Mucosal Adjuvant That Promotes Protective Immunity Against the Lethal Challenge with Enterovirus A71","volume":"11","author":"Lin","year":"2020","journal-title":"Front. Immunol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.bbrc.2014.05.019","article-title":"Antiviral effects of two Ganoderma lucidum triterpenoids against enterovirus 71 infection","volume":"449","author":"Zhang","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jbiosc.2011.09.005","article-title":"Cordysobin, a novel alkaline serine protease with HIV-1 reverse transcriptase inhibitory activity from the medicinal mushroom Cordyceps sobolifera","volume":"113","author":"Wang","year":"2012","journal-title":"J. Biosci. Bioeng."},{"key":"ref_34","first-page":"417","article-title":"In Vitro Anti-HIV-1 Activity of Cordyceps sinensis Extracts","volume":"32","author":"Zhu","year":"2016","journal-title":"Bing Du Xue Bao"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.phymed.2010.04.010","article-title":"Isolation of adenosine, iso-sinensetin and dimethylguanosine with antioxidant and HIV-1 protease inhibiting activities from fruiting bodies of Cordyceps militaris","volume":"18","author":"Jiang","year":"2011","journal-title":"Phytomedicine"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1042\/BSR20080153","article-title":"A haemagglutinin from the medicinal fungus Cordyceps militaris","volume":"29","author":"Wong","year":"2009","journal-title":"Biosci. Rep."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.bbagen.2007.09.004","article-title":"A novel lectin with potent antitumor, mitogenic and HIV-1 reverse transcriptase inhibitory activities from the edible mushroom Pleurotus citrinopileatus","volume":"1780","author":"Li","year":"2008","journal-title":"Biochim Biophys Acta"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s00253-008-1639-3","article-title":"Marmorin, a new ribosome inactivating protein with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from the mushroom Hypsizigus marmoreus","volume":"81","author":"Wong","year":"2008","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1016\/S0024-3205(01)01023-2","article-title":"Isolation and characterization of velutin, a novel low-molecular-weight ribosome-inactivating protein from winter mushroom (Flammulina velutipes) fruiting bodies","volume":"68","author":"Wang","year":"2001","journal-title":"Life Sci."},{"key":"ref_40","first-page":"115","article-title":"Schizolysin, a hemolysin from the split gill mushroom Schizophyllum commune","volume":"309","author":"Han","year":"2010","journal-title":"FEMS Microbiol. Lett."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s12275-011-1098-x","article-title":"A novel ribonuclease with potent HIV-1 reverse transcriptase inhibitory activity from cultured mushroom Schizophyllum commune","volume":"49","author":"Zhao","year":"2011","journal-title":"J. Microbiol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1615\/IntJMedMushrooms.2021038682","article-title":"Chemical Compounds and Computational Prediction of Their Inhibitory Effects on the HIV-1 gp120 Receptor by Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), with Antler-Like Morphology of Fruiting Bodies","volume":"23","author":"Cheng","year":"2021","journal-title":"Int. J. Med. Mushrooms"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"413","DOI":"10.6026\/97320630007413","article-title":"Interaction of ganoderic acid on HIV related target: Molecular docking studies","volume":"7","author":"Akbar","year":"2011","journal-title":"Bioinformation"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1248\/cpb.46.1607","article-title":"Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease","volume":"46","author":"Min","year":"1998","journal-title":"Chem. Pharm. Bull."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1016\/S0031-9422(98)00254-4","article-title":"Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum","volume":"49","author":"Meselhy","year":"1998","journal-title":"Phytochemistry"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"PL383","DOI":"10.1016\/S0024-3205(97)00294-4","article-title":"Polysaccharopeptide from Coriolus versicolor has potential for use against human immunodeficiency virus type 1 infection","volume":"60","author":"Collins","year":"1997","journal-title":"Life Sci."},{"key":"ref_47","first-page":"8741698","article-title":"Naturally Derived Anti-HIV Polysaccharide Peptide (PSP) Triggers a Toll-Like Receptor 4-Dependent Antiviral Immune Response","volume":"2018","author":"Lopez","year":"2018","journal-title":"J. Immunol. Res."},{"key":"ref_48","first-page":"88","article-title":"Isolation of a laccase with HIV-1 reverse transcriptase inhibitory activity from fresh fruiting bodies of the Lentinus edodes (Shiitake mushroom)","volume":"48","author":"Sun","year":"2011","journal-title":"Indian J. Biochem. Biophys."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"3363","DOI":"10.1016\/j.lfs.2003.06.023","article-title":"Lentin, a novel and potent antifungal protein from shitake mushroom with inhibitory effects on activity of human immunodeficiency virus-1 reverse transcriptase and proliferation of leukemia cells","volume":"73","author":"Ngai","year":"2003","journal-title":"Life Sci."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/0006-291X(89)91665-3","article-title":"Inhibition of the infectivity and cytopathic effect of human immunodeficiency virus by water-soluble lignin in an extract of the culture medium of Lentinus edodes mycelia (LEM)","volume":"160","author":"Suzuki","year":"1989","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/BF00189409","article-title":"Inhibition (in vitro) of replication and of the cytopathic effect of human immunodeficiency virus by an extract of the culture medium of Lentinus edodes mycelia","volume":"177","author":"Tochikura","year":"1988","journal-title":"Med. Microbiol. Immunol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1615\/IntJMedMushr.v16.i2.80","article-title":"Inhibitory Activity of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes) on Transformed Cells by Human Papillomavirus","volume":"16","author":"Gariglio","year":"2014","journal-title":"Int. J. Med. Mushrooms"},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Palacios, S., Losa, F., Dexeus, D., and Cortes, J. (2017). Beneficial effects of a Coriolus versicolor-based vaginal gel on cervical epithelization, vaginal microbiota and vaginal health: A pilot study in asymptomatic women. BMC Womens Health, 17.","DOI":"10.1186\/s12905-017-0374-2"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.ibmb.2011.11.005","article-title":"The entomopathogenic fungus Beauveria bassiana activate toll and JAK-STAT pathway-controlled effector genes and anti-dengue activity in Aedes aegypti","volume":"42","author":"Dong","year":"2012","journal-title":"Insect Biochem. Mol. Biol."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Panya, A., Songprakhon, P., Panwong, S., Jantakee, K., Kaewkod, T., Tragoolpua, Y., Sawasdee, N., Lee, V.S., Nimmanpipug, P., and Yenchitsomanus, P.T. (2021). Cordycepin Inhibits Virus Replication in Dengue Virus-Infected Vero Cells. Molecules, 26.","DOI":"10.3390\/molecules26113118"},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Ellan, K., Thayan, R., Raman, J., Hidari, K., Ismail, N., and Sabaratnam, V. (2019). Anti-viral activity of culinary and medicinal mushroom extracts against dengue virus serotype 2: An in-vitro study. BMC Complement. Altern. Med., 19.","DOI":"10.1186\/s12906-019-2629-y"},{"key":"ref_57","first-page":"1087","article-title":"Anti-inflammatory effect of mushrooms in dengue-infected human monocytes","volume":"36","author":"Ellan","year":"2019","journal-title":"Trop. Biomed."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"4273","DOI":"10.1080\/07391102.2019.1678523","article-title":"The identification of active compounds in Ganoderma lucidum var. antler extract inhibiting dengue virus serine protease and its computational studies","volume":"38","author":"Lim","year":"2020","journal-title":"J. Biomol. Struct. Dyn."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"19059","DOI":"10.1038\/s41598-019-55723-5","article-title":"Discovery of Ganoderma lucidum triterpenoids as potential inhibitors against Dengue virus NS2B-NS3 protease","volume":"9","author":"Bharadwaj","year":"2019","journal-title":"Sci. Rep."},{"key":"ref_60","first-page":"1261","article-title":"Cordyceps sinensis attenuates HBx-induced cell apoptosis in HK-2 cells through suppressing the PI3K\/Akt pathway","volume":"45","author":"He","year":"2020","journal-title":"Int. J. Mol. Med."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.antiviral.2006.05.011","article-title":"Inhibition of hepatitis B virus by D-fraction from Grifola frondosa: Synergistic effect of combination with interferon-alpha in HepG2 2.2.15","volume":"72","author":"Gu","year":"2006","journal-title":"Antiviral. Res."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/bs.pmbts.2019.03.012","article-title":"The efficacy of Polyporus Umbellatus polysaccharide in treating hepatitis B in China","volume":"163","author":"Guo","year":"2019","journal-title":"Prog. Mol. Biol. Transl. Sci."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/0192-0561(91)90050-H","article-title":"Effect of sizofiran, a polysaccharide, on interferon gamma, antibody production and lymphocyte proliferation specific for hepatitis B virus antigen in patients with chronic hepatitis B","volume":"13","author":"Kakumu","year":"1991","journal-title":"Int. J. Immunopharmacol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1142\/S0192415X06003874","article-title":"Anti-hepatitis activities in the broth of Ganoderma lucidum supplemented with a Chinese herbal medicine","volume":"34","author":"Li","year":"2006","journal-title":"Am. J. Chin. Med."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1007\/s10529-006-9007-9","article-title":"Anti-hepatitis B activities of ganoderic acid from Ganoderma lucidum","volume":"28","author":"Li","year":"2006","journal-title":"Biotechnol. Lett."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1016\/j.ijbiomac.2017.10.100","article-title":"Ultrasound assisted extraction of polysaccharides from Lentinus edodes and its anti-hepatitis B activity in vitro","volume":"107","author":"Zhao","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.bbrc.2015.04.104","article-title":"Anti-HCV effect of Lentinula edodes mycelia solid culture extracts and low-molecular-weight lignin","volume":"462","author":"Matsuhisa","year":"2015","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.bbrc.2014.03.150","article-title":"Anti-HCV activity of the Chinese medicinal fungus Cordyceps militaris","volume":"447","author":"Ueda","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.antiviral.2007.03.011","article-title":"Isolation, identification and function of a novel anti-HSV-1 protein from Grifola frondosa","volume":"75","author":"Gu","year":"2007","journal-title":"Antivir. Res."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0166-3542(93)90073-R","article-title":"Antiviral effect of the extract of culture medium of Lentinus edodes mycelia on the replication of herpes simplex virus type 1","volume":"20","author":"Sarkar","year":"1993","journal-title":"Antivir. Res."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0378-8741(00)00266-X","article-title":"Possible mode of antiviral activity of acidic protein bound polysaccharide isolated from Ganoderma lucidum on herpes simplex viruses","volume":"72","author":"Eo","year":"2000","journal-title":"J. Ethnopharmacol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0378-8741(00)00263-4","article-title":"Antiherpetic activities of acidic protein bound polysaccharide isolated from Ganoderma lucidum alone and in combinations with interferons","volume":"72","author":"Kim","year":"2000","journal-title":"J. Ethnopharmacol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0378-8741(00)00254-3","article-title":"Antiherpetic activities of acidic protein bound polysacchride isolated from Ganoderma lucidum alone and in combinations with acyclovir and vidarabine","volume":"72","author":"Oh","year":"2000","journal-title":"J. Ethnopharmacol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0378-8741(99)00067-7","article-title":"Antiviral activities of various water and methanol soluble substances isolated from Ganoderma lucidum","volume":"68","author":"Eo","year":"1999","journal-title":"J. Ethnopharmacol."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1089\/acm.2006.6297","article-title":"Herbal mixtures containing the mushroom Ganoderma lucidum improve recovery time in patients with herpes genitalis and labialis","volume":"13","author":"Hijikata","year":"2007","journal-title":"J. Altern. Complement. Med."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"866","DOI":"10.18632\/oncoscience.110","article-title":"Cordycepin is a novel chemical suppressor of Epstein-Barr virus replication","volume":"1","author":"Ryu","year":"2014","journal-title":"Oncoscience"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1021\/np0302293","article-title":"Lucidenic acids P and Q, methyl lucidenate P, and other triterpenoids from the fungus Ganoderma lucidum and their inhibitory effects on Epstein-Barr virus activation","volume":"66","author":"Iwatsuki","year":"2003","journal-title":"J. Nat. Prod."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"3273","DOI":"10.3892\/etm.2017.4883","article-title":"Triterpenoids from Ganoderma lucidum inhibit the activation of EBV antigens as telomerase inhibitors","volume":"14","author":"Zheng","year":"2017","journal-title":"Exp. Ther. Med."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.antiviral.2014.08.006","article-title":"Alleviation of respiratory syncytial virus replication and inflammation by fungal immunomodulatory protein FIP-fve from Flammulina velutipes","volume":"110","author":"Chang","year":"2014","journal-title":"Antivir. Res."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/1743-422X-9-37","article-title":"Polysaccharide and extracts from Lentinula edodes: Structural features and antiviral activity","volume":"9","author":"Rincao","year":"2012","journal-title":"Virol. J."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"197638","DOI":"10.1016\/j.virusres.2019.06.001","article-title":"Adjuvant activity of PCP-II, a polysaccharide from Poria cocos, on a whole killed rabies vaccine","volume":"270","author":"Zhang","year":"2019","journal-title":"Virus Res."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1186\/s12985-017-0869-3","article-title":"Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells induces immune responses in mice","volume":"14","author":"Gai","year":"2017","journal-title":"Virol. J."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1002\/jmv.24832","article-title":"Marburg virus-like particles produced in insect cells induce neutralizing antibodies in rhesus macaques","volume":"89","author":"Weiwei","year":"2017","journal-title":"J. Med. Virol."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/j.ijbiomac.2018.04.132","article-title":"Structural characterization and antiviral activity of lentinan from Lentinus edodes mycelia against infectious hematopoietic necrosis virus","volume":"115","author":"Ren","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.ijbiomac.2017.09.092","article-title":"Hericium erinaceus polysaccharide facilitates restoration of injured intestinal mucosal immunity in Muscovy duck reovirus-infected Muscovy ducklings","volume":"107","author":"Wu","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.ijbiomac.2020.12.222","article-title":"Effects of Hericium erinaceus polysaccharide on immunity and apoptosis of the main immune organs in Muscovy duck reovirus-infected ducklings","volume":"171","author":"Liu","year":"2021","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.ijbiomac.2019.08.130","article-title":"Transcriptome analysis of the effects of Hericium erinaceus polysaccharide on the lymphocyte homing in Muscovy duck reovirus-infected ducklings","volume":"140","author":"Liu","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S1050-4648(02)00167-5","article-title":"Dietary \u03b2-1,3-glucan effectively improves immunity and survival of Penaeus monodon challenged with white spot syndrome virus","volume":"15","author":"Chang","year":"2003","journal-title":"Fish Shellfish Immunol."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.14202\/vetworld.2020.1798-1806","article-title":"Anti-feline immunodeficiency virus reverse transcriptase properties of some medicinal and edible mushrooms","volume":"13","author":"Seetaha","year":"2020","journal-title":"Vet. World"},{"key":"ref_90","doi-asserted-by":"crossref","unstructured":"Forzan, M., Pacini, M.I., Bonaccini, P., and Mazzei, M. (2021). Antiviral effect of a commercially phytotherapeutic compound against feline immunodeficiency virus. Nat. Prod. Res.","DOI":"10.1080\/14786419.2021.1960329"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"13936","DOI":"10.1038\/s41598-018-32194-8","article-title":"Extracts of Polypore Mushroom Mycelia Reduce Viruses in Honey Bees","volume":"8","author":"Stamets","year":"2018","journal-title":"Sci. Rep."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.fsi.2012.02.008","article-title":"Administration of recombinant Reishi immunomodulatory protein (rLZ-8) diet enhances innate immune responses and elicits protection against nervous necrosis virus in grouper Epinephelus coioides","volume":"32","author":"Kuan","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1016\/j.ijbiomac.2019.09.079","article-title":"Adjuvanticity of Ganoderma lucidum polysaccharide liposomes on porcine circovirus type-II in mice","volume":"141","author":"Liu","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_94","doi-asserted-by":"crossref","unstructured":"Ma, Z., Zhang, W., Wang, L., Zhu, M., Wang, H., Feng, W.H., and Ng, T.B. (2013). A novel compound from the mushroom Cryptoporus volvatus inhibits porcine reproductive and respiratory syndrome virus (PRRSV) in vitro. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0079333"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1007\/s12272-016-0754-4","article-title":"Chemical constituents from the fruiting bodies of Cryptoporus volvatus","volume":"39","author":"Wang","year":"2016","journal-title":"Arch. Pharm. Res."},{"key":"ref_96","doi-asserted-by":"crossref","unstructured":"Gao, L., Zhang, W., Sun, Y., Yang, Q., Ren, J., Liu, J., Wang, H., and Feng, W.H. (2013). Cryptoporus volvatus extract inhibits porcine reproductive and respiratory syndrome virus (PRRSV) in vitro and in vivo. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0063767"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"107317","DOI":"10.1016\/j.intimp.2020.107317","article-title":"Ergosterol peroxide exhibits antiviral and immunomodulatory abilities against porcine deltacoronavirus (PDCoV) via suppression of NF-kappaB and p38\/MAPK signaling pathways in vitro","volume":"93","author":"Duan","year":"2021","journal-title":"Int. Immunopharmacol."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/s13567-021-00955-5","article-title":"Antiviral effects of ergosterol peroxide in a pig model of porcine deltacoronavirus (PDCoV) infection involves modulation of apoptosis and tight junction in the small intestine","volume":"52","author":"Duan","year":"2021","journal-title":"Vet. Res."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1615\/IntJMedMushrooms.v16.i6.70","article-title":"Methanolic Soluble Fractions of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes) Extract Inhibit Neuraminidase Activity in Newcastle Disease Virus (LaSota)","volume":"16","author":"Shamaki","year":"2014","journal-title":"Int. J. Med. Mushrooms"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.ijbiomac.2014.01.067","article-title":"The adjuvanticity of Ganoderma lucidum polysaccharide for Newcastle disease vaccine","volume":"65","author":"Zhang","year":"2014","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1016\/j.carbpol.2012.06.060","article-title":"In vitro antiviral activity of sulfated Auricularia auricula polysaccharides","volume":"90","author":"Nguyen","year":"2012","journal-title":"Carbohydr. Polym."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.ijbiomac.2013.04.007","article-title":"Cordyceps militaris polysaccharides can improve the immune efficacy of Newcastle disease vaccine in chicken","volume":"59","author":"Wang","year":"2013","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1080\/10286020.2013.874346","article-title":"Two new steroids from sclerotia of the fungus Omphalia lapidescens","volume":"16","author":"Yan","year":"2014","journal-title":"J. Asian Nat. Prod. Res."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1271\/bbb.57.278","article-title":"Antiviral Substances with Systemic Effects Produced by Basidiomycetes such as Fomes fomentarius","volume":"57","author":"Aoki","year":"1993","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.ijbiomac.2013.07.005","article-title":"Inhibitory effect of sulfated lentinan and lentinan against tobacco mosaic virus (TMV) in tobacco seedlings","volume":"61","author":"Wang","year":"2013","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"104570","DOI":"10.1016\/j.pestbp.2020.104570","article-title":"Antiviral activity of basidiomycetous fungi against Groundnut bud necrosis virus in tomato","volume":"166","author":"Sangeetha","year":"2020","journal-title":"Pestic. Biochem. Physiol."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1001\/jama.2020.3072","article-title":"COVID-19-New Insights on a Rapidly Changing Epidemic","volume":"323","author":"Malani","year":"2020","journal-title":"JAMA"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1002\/jmv.27491","article-title":"Omicron variant (B.1.1.529) of SARS-CoV-2, a global urgent public health alert!","volume":"94","author":"Gao","year":"2022","journal-title":"J. Med. Virol."},{"key":"ref_109","first-page":"1","article-title":"Overview of influenza viruses","volume":"370","author":"Pleschka","year":"2013","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"64","DOI":"10.4065\/mcp.2009.0588","article-title":"2009 H1N1 influenza","volume":"85","author":"Sullivan","year":"2010","journal-title":"Mayo. Clin. Proc."},{"key":"ref_111","first-page":"751","article-title":"Influenza: Diagnosis and Treatment","volume":"100","author":"Gaitonde","year":"2019","journal-title":"Am. Fam. Physician"},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1007\/s12011-011-8986-0","article-title":"Determination of trace elements in anti-influenza virus mushrooms","volume":"143","author":"Wang","year":"2011","journal-title":"Biol. Trace Elem. Res."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"e739","DOI":"10.1016\/j.ijid.2009.12.002","article-title":"Enterovirus 71 vaccine: Close but still far","volume":"14","author":"Zhang","year":"2010","journal-title":"Int. J. Infect. Dis."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1086\/592988","article-title":"Enterovirus-associated encephalitis in the California encephalitis project, 1998\u20132005","volume":"198","author":"Fowlkes","year":"2008","journal-title":"J. Infect. Dis."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1097\/QAD.0b013e328362ba67","article-title":"The burden of HIV: Insights from the Global Burden of Disease Study 2010","volume":"27","author":"Ortblad","year":"2013","journal-title":"AIDS"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1007\/s00705-021-05140-9","article-title":"Prevalence of transmitted HIV-1 drug resistance among treatment-naive individuals in China, 2000\u20132016","volume":"166","author":"Yuan","year":"2021","journal-title":"Arch. Virol."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.idc.2013.09.001","article-title":"HPV and HPV-associated diseases","volume":"27","author":"Dunne","year":"2013","journal-title":"Infect. Dis. Clin. N. Am."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s12929-016-0293-9","article-title":"Perspectives for therapeutic HPV vaccine development","volume":"23","author":"Yang","year":"2016","journal-title":"J. Biomed. Sci."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1007\/s12325-020-01594-6","article-title":"Therapeutic Efficacy of a Coriolusversicolor-Based Vaginal Gel in Women with Cervical Uterine High-Risk HPV Infection: A Retrospective Observational Study","volume":"38","author":"Criscuolo","year":"2021","journal-title":"Adv. Ther."},{"key":"ref_120","doi-asserted-by":"crossref","unstructured":"Salazar, M.I., Richardson, J.H., Sanchez-Vargas, I., Olson, K.E., and Beaty, B.J. (2007). Dengue virus type 2: Replication and tropisms in orally infected Aedes aegypti mosquitoes. BMC Microbiol., 7.","DOI":"10.1186\/1471-2180-7-9"},{"key":"ref_121","doi-asserted-by":"crossref","unstructured":"Tian, J.N., Yang, C.C., Chuang, C.K., Tsai, M.H., Wu, R.H., Chen, C.T., and Yueh, A. (2019). A Dengue Virus Type 2 (DENV-2) NS4B-Interacting Host Factor, SERP1, Reduces DENV-2 Production by Suppressing Viral RNA Replication. Viruses, 11.","DOI":"10.3390\/v11090787"},{"key":"ref_122","doi-asserted-by":"crossref","unstructured":"Nanaware, N., Banerjee, A., Mullick Bagchi, S., Bagchi, P., and Mukherjee, A. (2021). Dengue Virus Infection: A Tale of Viral Exploitations and Host Responses. Viruses, 13.","DOI":"10.3390\/v13101967"},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s12223-016-0482-7","article-title":"Herpesvirus: An underestimated virus","volume":"62","author":"Rechenchoski","year":"2017","journal-title":"Folia Microbio."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/B978-0-444-53488-0.00011-0","article-title":"Herpes simplex virus","volume":"123","author":"Widener","year":"2014","journal-title":"Handb. Clin. Neurol."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1615\/IntJMedMushrooms.2018025468","article-title":"In Vitro Evaluation of the Antiviral Activity of Some Mushrooms from Turkey","volume":"20","author":"Dogan","year":"2018","journal-title":"Int. J. Med. Mushrooms"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"509","DOI":"10.3892\/ijmm.2020.4641","article-title":"Update on current views and advances on RSV infection (Review)","volume":"46","author":"Mammas","year":"2020","journal-title":"Int. J. Mol. Med."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s40121-020-00387-2","article-title":"Current State of Respiratory Syncytial Virus Disease and Management","volume":"10","author":"Chatterjee","year":"2021","journal-title":"Infect. Dis. Ther."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.virol.2005.09.015","article-title":"One hundred years of poliovirus pathogenesis","volume":"344","author":"Racaniello","year":"2006","journal-title":"Virology"},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-3527(08)00001-8","article-title":"Chapter 1 The Pathogenesis of Poliomyelitis: What We Don\u2019t Know","volume":"71","author":"Nathanson","year":"2008","journal-title":"Adv. Virus Res."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1146\/annurev-virology-100114-055157","article-title":"Everything You Always Wanted to Know About Rabies Virus (But Were Afraid to Ask)","volume":"2","author":"Davis","year":"2015","journal-title":"Annu. Rev. Virol."},{"key":"ref_131","doi-asserted-by":"crossref","unstructured":"Stitz, L., Vogel, A., Schnee, M., Voss, D., Rauch, S., Mutzke, T., Ketterer, T., Kramps, T., and Petsch, B. (2017). A thermostable messenger RNA based vaccine against rabies. PLoS Negl. Trop. Dis., 11.","DOI":"10.1371\/journal.pntd.0006108"},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s12250-019-00184-3","article-title":"Screening and Identification of Marburg Virus Entry Inhibitors Using Approved Drugs","volume":"35","author":"Zhang","year":"2020","journal-title":"Virol. Sin."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/s13567-016-0341-1","article-title":"Epidemiological characteristics of infectious hematopoietic necrosis virus (IHNV): A review","volume":"47","author":"Dixon","year":"2016","journal-title":"Vet. Res."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1007\/s00284-019-01865-8","article-title":"Muscovy Duck Reovirus Infection Disrupts the Composition of Intestinal Microbiota in Muscovy Ducklings","volume":"77","author":"Chen","year":"2020","journal-title":"Curr. Microbiol."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.fsi.2019.08.011","article-title":"Cellular entry of white spot syndrome virus and antiviral immunity mediated by cellular receptors in crustaceans","volume":"93","author":"Zheng","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"370","DOI":"10.2741\/1235","article-title":"Feline immunodeficiency virus: A concise review","volume":"9","author":"Kanzaki","year":"2004","journal-title":"Front. Biosci. -Landmark"},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"S48","DOI":"10.1016\/j.jip.2009.06.012","article-title":"Deformed wing virus","volume":"103","author":"Genersch","year":"2010","journal-title":"J. Invertebr. Pathol."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.fsi.2019.11.053","article-title":"Red grouper nervous necrosis virus (RGNNV) induces autophagy to promote viral replication","volume":"98","author":"Li","year":"2020","journal-title":"Fish Shellfish Immunol."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"108653","DOI":"10.1016\/j.vetmic.2020.108653","article-title":"Coinfection with porcine circovirus type 2 and Streptococcus suis serotype 2 enhances pathogenicity by dysregulation of the immune responses in piglets","volume":"243","author":"Wang","year":"2020","journal-title":"Vet. Microbiol."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1146\/annurev-animal-022114-111025","article-title":"Porcine Reproductive and Respiratory Syndrome Virus (PRRSV): Pathogenesis and Interaction with the Immune System","volume":"4","author":"Lunney","year":"2016","journal-title":"Annu. Rev. Anim. Biosci."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.virusres.2016.05.028","article-title":"Porcine deltacoronavirus: Overview of infection dynamics, diagnostic methods, prevalence and genetic evolution","volume":"226","author":"Zhang","year":"2016","journal-title":"Virus. Res."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1051\/vetres:2006059","article-title":"Bovine herpesvirus 1 infection and infectious bovine rhinotracheitis","volume":"38","author":"Muylkens","year":"2007","journal-title":"Vet. Res."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.virusres.2014.02.016","article-title":"Newcastle disease virus: Current status and our understanding","volume":"184","author":"Ganar","year":"2014","journal-title":"Virus Res."},{"key":"ref_144","doi-asserted-by":"crossref","unstructured":"Lu, Z.S., Chen, Q.S., Zheng, Q.X., Shen, J.J., Luo, Z.P., Fan, K., Xu, S.H., Shen, Q., and Liu, P.P. (2019). Proteomic and Phosphoproteomic Analysis in Tobacco Mosaic Virus-Infected Tobacco (Nicotiana tabacum). Biomolecules, 9.","DOI":"10.3390\/biom9020039"},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.ijbiomac.2021.08.143","article-title":"Molecular modelling of coat protein of the Groundnut bud necrosis tospovirus and its binding with Squalene as an antiviral agent: In vitro and in silico docking investigations","volume":"189","author":"Sangeetha","year":"2021","journal-title":"Int. J. Biol. Macromol."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/27\/14\/4457\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:49:00Z","timestamp":1760140140000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/27\/14\/4457"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,12]]},"references-count":145,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2022,7]]}},"alternative-id":["molecules27144457"],"URL":"https:\/\/doi.org\/10.3390\/molecules27144457","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,12]]}}}