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Yet, lactose intolerance conditions demand low-lactose and lactose-free products in the market. These increasing nutritional claims and labels on food products entail simple and reliable methods of analysis that can be used for meeting quality standards, nutritional claims and legal requirements. In this study, terahertz time\u2013domain spectroscopy (THz-TDS) was employed to analyse \u03b1-lactose monohydrate qualitatively and quantitatively in food products. Both absorption spectra and absorption coefficient spectra were investigated for their prediction performance. Regression models for lactose quantification using peak area and height of the absorption peaks 0.53 and 1.37 THz were developed and assessed in infant formula samples. Satisfactory prediction results were achieved in ideal conditions with pure standards, but not in all predictions of infant formula samples. Reasons and further implications are discussed.<\/jats:p>","DOI":"10.3390\/molecules27155040","type":"journal-article","created":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T22:33:11Z","timestamp":1659997991000},"page":"5040","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Terahertz Spectroscopic Analysis of Lactose in Infant Formula: Implications for Detection and Quantification"],"prefix":"10.3390","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8042-4513","authenticated-orcid":false,"given":"Sopanant","family":"Datta","sequence":"first","affiliation":[{"name":"Science Division, Mahidol University International College, Mahidol University, Salaya, Phutthamonthon, Nakhon Pathom 73170, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3798-9935","authenticated-orcid":false,"given":"Kiattiwut","family":"Prasertsuk","sequence":"additional","affiliation":[{"name":"National Electronics and Computer Technology, National Science and Technology Development Agency, 112 Thailand Science Park, Khlong Luang 12120, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2533-9505","authenticated-orcid":false,"given":"Nuttawat","family":"Khammata","sequence":"additional","affiliation":[{"name":"Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3345-1126","authenticated-orcid":false,"given":"Patharakorn","family":"Rattanawan","sequence":"additional","affiliation":[{"name":"National Electronics and Computer Technology, National Science and Technology Development Agency, 112 Thailand Science Park, Khlong Luang 12120, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5538-5030","authenticated-orcid":false,"given":"Jia Yi","family":"Chia","sequence":"additional","affiliation":[{"name":"National Electronics and Computer Technology, National Science and Technology Development Agency, 112 Thailand Science Park, Khlong Luang 12120, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4222-0808","authenticated-orcid":false,"given":"Rungroj","family":"Jintamethasawat","sequence":"additional","affiliation":[{"name":"National Electronics and Computer Technology, National Science and Technology Development Agency, 112 Thailand Science Park, Khlong Luang 12120, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7229-6857","authenticated-orcid":false,"given":"Thawatchart","family":"Chulapakorn","sequence":"additional","affiliation":[{"name":"National Electronics and Computer Technology, National Science and Technology Development Agency, 112 Thailand Science Park, Khlong Luang 12120, Thailand"},{"name":"Department of Construction Sciences, Lund University, 22100 Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8558-6199","authenticated-orcid":false,"given":"Taweetham","family":"Limpanuparb","sequence":"additional","affiliation":[{"name":"Science Division, Mahidol University International College, Mahidol University, Salaya, Phutthamonthon, Nakhon Pathom 73170, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,8]]},"reference":[{"key":"ref_1","unstructured":"Food and Agriculture Organizaion (2022, March 02). 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