{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T15:09:06Z","timestamp":1789744146743,"version":"4.0.1"},"reference-count":66,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2022,10,7]],"date-time":"2022-10-07T00:00:00Z","timestamp":1665100800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>We report on the green preparation of one-dimensional metal coordination polymers by sonochemical approach. The spacer ligand 4,4\u2032-bipyridine was ultrasonicated with chloride or acetate zinc salts to obtain [Zn(4,4\u2032-bipy)Cl2]\u221e and [Zn(4,4\u2032-bipy)2(OAc)2]\u221e, respectively. Benign solvents such as ethanol and water were selected as reaction media, and the synthesis took place in a few minutes\u2014a very short time compared to conventional methods where some days\u2019 synthesis is required. X-ray powder diffraction, Fourier transform infrared spectroscopy, thermal analysis (thermogravimetric and differential scanning calorimetry), and CHN techniques investigated the influence of using different reaction solvents on the chemical, structural, and thermal properties of the final products. The 1D [Zn(4,4\u2032-bipy)Cl2]\u221e and [Zn(4,4\u2032-bipy)2(OAc)2]\u221e polymers, in agreement with the structures reported in the literature, were obtained in the form of nanocrystals with an average crystal size around 100 nm. As a proof of concept, a set of Gram-positive (Staphylococcus aureus) and Gram-negative bacteria (Klebsiella pneumoniae), and three yeast strains (Candida albicans, Candida krusei, Candida glabrata) were tested to evaluate the antimicrobial activity of the coordination polymers, following the Kirby\u2013Bauer procedure and microplate dilution method. Thus, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and minimal biofilm inhibitory concentration (MBIC) were evaluated. Except for Candida krusei, the compounds showed an appreciable antimicrobial and antibiofilm activity against these strains grown in the liquid medium.<\/jats:p>","DOI":"10.3390\/molecules27196677","type":"journal-article","created":{"date-parts":[[2022,10,9]],"date-time":"2022-10-09T23:31:43Z","timestamp":1665358303000},"page":"6677","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Green Preparation of Antimicrobial 1D-Coordination Polymers: [Zn(4,4\u2032-bipy)Cl2]\u221e and [Zn(4,4\u2032-bipy)2(OAc)2]\u221e by Ultrasonication of Zn(II) Salts and 4,4\u2032-Bipyridine"],"prefix":"10.3390","volume":"27","author":[{"given":"Alessandra","family":"Scano","sequence":"first","affiliation":[{"name":"Department of Chemical and Geological Sciences, University of Cagliari and INSTM Unit, SS 554 Bivio per Sestu, 09042 Monserrato, CA, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Mereu","sequence":"additional","affiliation":[{"name":"Department of Chemical and Geological Sciences, University of Cagliari and INSTM Unit, SS 554 Bivio per Sestu, 09042 Monserrato, CA, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Cabras","sequence":"additional","affiliation":[{"name":"Department of Chemical and Geological Sciences, University of Cagliari and INSTM Unit, SS 554 Bivio per Sestu, 09042 Monserrato, CA, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8354-0608","authenticated-orcid":false,"given":"Giada","family":"Mannias","sequence":"additional","affiliation":[{"name":"Department of Chemical and Geological Sciences, University of Cagliari and INSTM Unit, SS 554 Bivio per Sestu, 09042 Monserrato, CA, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Garau","sequence":"additional","affiliation":[{"name":"Department of Chemical and Geological Sciences, University of Cagliari and INSTM Unit, SS 554 Bivio per Sestu, 09042 Monserrato, CA, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7598-7290","authenticated-orcid":false,"given":"Martina","family":"Pilloni","sequence":"additional","affiliation":[{"name":"Department of Chemical and Geological Sciences, University of Cagliari and INSTM Unit, SS 554 Bivio per Sestu, 09042 Monserrato, CA, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germano","family":"Orr\u00f9","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, Molecular Biology Service, University of Cagliari, 09124 Cagliari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4385-8002","authenticated-orcid":false,"given":"Alessandra","family":"Scano","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, Molecular Biology Service, University of Cagliari, 09124 Cagliari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2467-1514","authenticated-orcid":false,"given":"Guido","family":"Ennas","sequence":"additional","affiliation":[{"name":"Department of Chemical and Geological Sciences, University of Cagliari and INSTM Unit, SS 554 Bivio per Sestu, 09042 Monserrato, CA, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,7]]},"reference":[{"key":"ref_1","unstructured":"Batten, S.R., Turner, D.R., and Neville, M.S. 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