{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T08:19:19Z","timestamp":1762071559762,"version":"build-2065373602"},"reference-count":49,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T00:00:00Z","timestamp":1665532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Key R&amp;D Program of Hainan Province, China","award":["ZDYF2022SHFZ020","2022C02023","820RC585","HNSF-OP-2021-2"],"award-info":[{"award-number":["ZDYF2022SHFZ020","2022C02023","820RC585","HNSF-OP-2021-2"]}]},{"name":"\u201cPioneer\u201d and \u201cLeading Goose\u201d R&amp;D Program of Zhejiang","award":["ZDYF2022SHFZ020","2022C02023","820RC585","HNSF-OP-2021-2"],"award-info":[{"award-number":["ZDYF2022SHFZ020","2022C02023","820RC585","HNSF-OP-2021-2"]}]},{"name":"High-level talent project of Hainan Natural Science Foundation","award":["ZDYF2022SHFZ020","2022C02023","820RC585","HNSF-OP-2021-2"],"award-info":[{"award-number":["ZDYF2022SHFZ020","2022C02023","820RC585","HNSF-OP-2021-2"]}]},{"name":"Open Project of Ministry of Education Key Laboratory for Ecology of Tropical Islands, Hainan Normal University, China","award":["ZDYF2022SHFZ020","2022C02023","820RC585","HNSF-OP-2021-2"],"award-info":[{"award-number":["ZDYF2022SHFZ020","2022C02023","820RC585","HNSF-OP-2021-2"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Camellia vietnamensis Huang is an important woody oil crop in China, which has attracted much attention because of its abundant nutritional components and pharmaceutical value. Its seeds undergo a complex series of physiological and biochemical changes during maturation, with consequent alterations in metabolites. In order to investigate the endogenous metabolism of C. vietnamensis on Hainan Island during seed development, in this study, ultra-high-performance liquid tandem chromatography coupled with quadrupole time-of-flight mass spectrometry (UHPLC\/Q-TOF-MS) and multivariate statistical analysis (MSA) were used to analyze the differences in the chemical compounds of C. vietnamensis seeds among the four maturation stages. A total of 293 metabolites were identified from the methanol extract of the seeds of C. vietnamensis. Five metabolites, belonging to benzene and substituted derivatives, 5\u2032-deoxyribonucleosides and linear 1,3-diarylpropanoids, were found in all three comparison groups, with consistently down-regulated trends. The Kyoto Encyclopedia of Genes and Genomes (KEGG) results showed that phloretin and 5\u2032-methylthioadenosine were the differentially expressed metabolites when seeds were in the growth periods of S2 and S3, and indole and L-tryptophan were the differentially expressed metabolites when seeds were in the growth periods of S3 and S4. In addition, 34 flavonoid metabolites were detected, of which 4 were differentially expressed. It was indicated that flavonoids dynamically change during all the oil-tea camellia seed development stages. The findings provide data for the better understanding of endogenous metabolic pathways during C. vietnamensis seed development.<\/jats:p>","DOI":"10.3390\/molecules27206817","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T05:31:18Z","timestamp":1665552678000},"page":"6817","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Comparison of the Main Metabolites in Different Maturation Stages of Camelliavietnamensis Huang Seeds"],"prefix":"10.3390","volume":"27","author":[{"given":"Heqin","family":"Yan","sequence":"first","affiliation":[{"name":"Key Laboratory for Quality Regulation of Tropical Horticultural Plants of Hainan Province, College of Horticulture, Hainan University, Haikou 570228, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Zheng","sequence":"additional","affiliation":[{"name":"Key Laboratory for Quality Regulation of Tropical Horticultural Plants of Hainan Province, College of Horticulture, Hainan University, Haikou 570228, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhouchen","family":"Ye","sequence":"additional","affiliation":[{"name":"Key Laboratory for Quality Regulation of Tropical Horticultural Plants of Hainan Province, College of Horticulture, Hainan University, Haikou 570228, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6311-4214","authenticated-orcid":false,"given":"Jing","family":"Yu","sequence":"additional","affiliation":[{"name":"Key Laboratory for Quality Regulation of Tropical Horticultural Plants of Hainan Province, College of Horticulture, Hainan University, Haikou 570228, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yougen","family":"Wu","sequence":"additional","affiliation":[{"name":"College of Tropical Crops, Hainan University, Haikou 570228, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Feng, J.L., Yang, Z.J., Chen, S.P., El-Kassaby, Y.A., and Chen, H. 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