{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T07:10:29Z","timestamp":1792480229311,"version":"4.5.0"},"reference-count":45,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T00:00:00Z","timestamp":1666137600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>In the current study, the phytochemical constituents of volatile organic compounds (VOCs) obtained from Sida rhombifolia L. were identified by GC-FID and GC-MS analysis. A total of 73 volatile organic compounds were identified. The major components of S. rhombifolia VOCs were identified as palmitic acid (21.56%), phytol (7.02%), 6,10,14-trimethyl-2-pentadecanone (6.30%), oleic acid (5.48%), 2-pentyl-furan (5.23%), and linoleic acid (3.21%). The VOCs are rich in fatty acids (32.50%), olefine aldehyde (9.59%), ketone (9.41%), enol (9.02%), aldehyde (8.63%), and ketene (6.41%). The antioxidant capacity of S. rhombifolia VOCs was determined by 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH), 2,2-azinobis-(3-ethylbenzothiazolin-6-sulfonic acid) diammonium salt (ABTS), and ferric reducing\/antioxidant power (FRAP) methods with butylated hydroxytoluene (BHT) and Trolox as standard. The VOCs showed dose-dependent antioxidant activity with IC50 (50% inhibitory concentration) values of 5.48 \u00b1 0.024 and 1.47 \u00b1 0.012 mg\/mL for DPPH and ABTS assays, respectively. FRAP antioxidant capacity was 83.10 \u00b1 1.66 mM\/g. The results show that the VOCs distilled from S. rhombifolia have a moderate antioxidant property that can be utilized as a natural botanical supplement or an antioxidant.<\/jats:p>","DOI":"10.3390\/molecules27207067","type":"journal-article","created":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T22:19:53Z","timestamp":1666217993000},"page":"7067","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Chemical Composition and In Vitro Antioxidant Activity of Sida rhombifolia L. Volatile Organic Compounds"],"prefix":"10.3390","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8932-1190","authenticated-orcid":false,"given":"Ziyue","family":"Xu","sequence":"first","affiliation":[{"name":"SDU-ANU Joint Science College, Shandong University, Weihai 264209, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peizhong","family":"Gao","sequence":"additional","affiliation":[{"name":"SDU-ANU Joint Science College, Shandong University, Weihai 264209, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dun","family":"Liu","sequence":"additional","affiliation":[{"name":"SDU-ANU Joint Science College, Shandong University, Weihai 264209, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenzhi","family":"Song","sequence":"additional","affiliation":[{"name":"SDU-ANU Joint Science College, Shandong University, Weihai 264209, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingfan","family":"Zhu","sequence":"additional","affiliation":[{"name":"SDU-ANU Joint Science College, Shandong University, Weihai 264209, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4480-330X","authenticated-orcid":false,"given":"Xu","family":"Liu","sequence":"additional","affiliation":[{"name":"Marine College, Shandong University, Weihai 264209, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"384","DOI":"10.3390\/antiox2040384","article-title":"Chemical Composition and Antioxidant Activity of Essential Oils from Cinnamodendron dinisii Schwacke and Siparuna guianensis Aublet","volume":"2","author":"Andrade","year":"2013","journal-title":"Antioxidants"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Thomford, N.E., Senthebane, D.A., Rowe, A., Munro, D., Seele, P., Maroyi, A., and Dzobo, K. 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