{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T03:27:13Z","timestamp":1791948433924,"version":"4.3.4"},"reference-count":152,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T00:00:00Z","timestamp":1666915200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"French Agence Nationale de la Recherche","award":["2020 07132"],"award-info":[{"award-number":["2020 07132"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Plants are a promising source of bioactive compounds that can be used to tackle many emerging diseases both infectious and non-infectious. Among different plants, Acacia is a very large genus and exhibits a diverse array of bioactive agents with remarkable pharmacological properties against different diseases. Acacia, a herb found all over the world, contains approximately more than 1200 species of the Fabaceae family. In the present review, we have collected detailed information on biochemical as well as pharmacological properties. The data were retrieved using different databases, such as Elsevier, PubMed, Science Direct, Google Scholar, and Scopus, and an extensive literature survey was carried out. Studies have shown that Acacia possesses several secondary metabolites, including amines, cyanogenic glycosides, flavonoids, alkaloids, seed oils, cyclitols, fluoroacetate, gums, non-protein amino acids, diterpenes, fatty acids, terpenes, hydrolyzable tannins, and condensed tannins. These compounds exhibit a wide range of pharmaceutical applications such as anti-inflammatory, antioxidant, antidiarrheal, antidiabetic, anticancer, antiviral, liver protective effects, and so on. Thus, the literature shows the tremendous phytochemical impact of the genus Acacia in medicine. Overall, we recommend that more research should be conducted on the medicinal value and isolation and purification of the effective therapeutic agents from Acacia species for the treatment of various ailments.<\/jats:p>","DOI":"10.3390\/molecules27217340","type":"journal-article","created":{"date-parts":[[2022,10,30]],"date-time":"2022-10-30T09:01:42Z","timestamp":1667120502000},"page":"7340","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":72,"title":["Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Genus Acacia"],"prefix":"10.3390","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7817-425X","authenticated-orcid":false,"given":"Gaber El-Saber","family":"Batiha","sequence":"first","affiliation":[{"name":"Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3413-9150","authenticated-orcid":false,"given":"Nosheen","family":"Akhtar","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, National University of Medical Sciences, Islamabad 46000, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman A.","family":"Alsayegh","sequence":"additional","affiliation":[{"name":"Clinical Nutrition Department, Applied Medical Sciences College, Jazan University, Jazan 82817, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wafaa Fouzi","family":"Abusudah","sequence":"additional","affiliation":[{"name":"Clinical Nutrition Department, College of Applied Medical Sciences, Umm Al-Qura University, Makkah 24381, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najlaa Hamed","family":"Almohmadi","sequence":"additional","affiliation":[{"name":"Clinical Nutrition Department, College of Applied Medical Sciences, Umm Al-Qura University, Makkah 24381, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hazem M.","family":"Shaheen","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thakur Gurjeet","family":"Singh","sequence":"additional","affiliation":[{"name":"Chitkara College of Pharmacy, Chitkara University, Punjab 140401, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"De Waard","sequence":"additional","affiliation":[{"name":"Smartox Biotechnology, 6 rue des Platanes, 38120 Saint-Egr\u00e8ve, France"},{"name":"L\u2019institut du Thorax, INSERM, CNRS, Universit\u00e9 de Nantes, 44007 Nantes, France"},{"name":"LabEx \u00abIon Channels, Science & Therapeutics\u00bb, Universit\u00e9 de Nice Sophia-Antipolis, 06560 Valbonne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,28]]},"reference":[{"key":"ref_1","unstructured":"Maslin, B., Orchard, A., and West, J. (2003). Nomenclatural and Classification History of Acacia (Leguminosae: Mimosoideae), and the Implications of Generic Subdivision, Department of Conservation & Land Management."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.foodhyd.2017.04.008","article-title":"Acacia gum: History of the future","volume":"78","author":"Sanchez","year":"2018","journal-title":"Food Hydrocoll."},{"key":"ref_3","first-page":"292","article-title":"Antifungal activity of polyphenolic complex of Acacia nilotica bark","volume":"124","author":"Bhargava","year":"1998","journal-title":"Indian For."},{"key":"ref_4","first-page":"377","article-title":"Antifungal activity of fluid extract and essential oil from anise fruits (Pimpinella anisum L., Apiaceae)","volume":"55","author":"Kosalec","year":"2005","journal-title":"Acta Pharm."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1186\/s12906-017-1878-x","article-title":"In vitro antioxidant and antimalarial activities of leaves, pods and bark extracts of Acacia nilotica (L.) Del","volume":"17","author":"Sadiq","year":"2017","journal-title":"BMC Complement. Alter. Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.sjbs.2014.03.005","article-title":"Metabolomic profiling and antioxidant activity of some Acacia species","volume":"21","author":"Sheded","year":"2014","journal-title":"Saudi J. Biol. Sci."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1016\/j.jsps.2017.09.010","article-title":"Comparative anticancer and antimicrobial activity of aerial parts of Acacia salicina, Acacia laeta, Acacia hamulosa and Acacia tortilis grown in Saudi Arabia","volume":"25","author":"Alajmi","year":"2017","journal-title":"Saudi Pharm. J."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/S0305-1978(03)00082-6","article-title":"Phytochemistry of Acacia\u2014sensu lato","volume":"31","author":"Seigler","year":"2003","journal-title":"Biochem. Syst. Ecol."},{"key":"ref_9","first-page":"665","article-title":"Studies on antihypertensive and antispasmodic activities of methanol extract of Acacia nilotica pods","volume":"13","author":"Gilani","year":"1999","journal-title":"Phytother. Res. Int. J. Devoted Pharmacol. Toxicol. Eval. Nat. Product Deriva."},{"key":"ref_10","first-page":"80","article-title":"Evaluation of Antimicrobial Potentiality of 50% Aqueous Ethanoloic Leaf Extract of Clitoria ternatea L.","volume":"7","author":"Das","year":"2014","journal-title":"Asian J. Pharm. Clin. Research. Innovare Acad."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e252526","DOI":"10.1590\/1519-6984.252526","article-title":"Evaluation of in vitro anticancer potential of pharmacological ethanolic plant extracts Acacia modesta and Opuntia monocantha against liver cancer cells","volume":"84","author":"Abid","year":"2022","journal-title":"Braz. J. Biol."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Afsar, T., Khan, M.R., Razak, S., Ullah, S., and Mirza, B. (2015). Antipyretic, anti-inflammatory and analgesic activity of Acacia hydaspica R. Parker and its phytochemical analysis. BMC Complement. Altern. Med., 15.","DOI":"10.1186\/s12906-015-0658-8"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1021\/jf072922s","article-title":"Effect of Phytocompounds from the Heartwood of Acacia confusa on Inflammatory Mediator Production","volume":"56","author":"Wu","year":"2008","journal-title":"J. Agric. Food Chem."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"100616","DOI":"10.1016\/j.fbio.2020.100616","article-title":"Phenolic profiling, biological activities and in silico studies of Acacia tortilis (Forssk.) Hayne ssp. raddiana extracts","volume":"36","author":"Ziani","year":"2020","journal-title":"Food Biosci."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"46","DOI":"10.4314\/ajtcam.v5i1.31255","article-title":"In vivo screening of antimalarial activity of Acacia mellifera (Benth)(Leguminosae) on Plasmodium berghei in mice","volume":"5","author":"Mutai","year":"2008","journal-title":"Afr. J. Tradit. Complement. Alter. Med."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Amoussa, A.M.O., Lagnika, L., Bourjot, M., Vonthron-Senecheau, C., and Sanni, A. (2016). Triterpenoids from Acacia ataxacantha DC: Antimicrobial and antioxidant activities. BMC Complement. Altern. Med., 16.","DOI":"10.1186\/s12906-016-1266-y"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s12906-018-2113-0","article-title":"Acacia hydaspica R. Parker ameliorates cisplatin induced oxidative stress, DNA damage and morphological alterations in rat pulmonary tissue","volume":"18","author":"Afsar","year":"2018","journal-title":"Complement. Altern. Med."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.phytol.2012.11.008","article-title":"Loranthin: A new polyhydroxylated flavanocoumarin from Plicosepalus acacia with significant free radical scavenging and antimicrobial activity","volume":"6","author":"Badr","year":"2013","journal-title":"Phytochem. Lett."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1111\/jam.12328","article-title":"Isolation, characterization and mode of antimicrobial action against Vibrio cholerae of methyl gallate isolated from Acacia farnesiana","volume":"115","author":"Heredia","year":"2013","journal-title":"J. Appl. Microbiol."},{"key":"ref_20","first-page":"37","article-title":"LC\/TOF\/ESI\/MS based detection of bioactive compounds present in leaf and bark extract of Acacia arabica","volume":"5","author":"Deboshree","year":"2013","journal-title":"Recent Res. Sci. Technol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"S417","DOI":"10.12980\/APJTB.4.2014C1038","article-title":"Antioxidant and anti\u2013acetylcholinesterase activities of extracts and secondary metabolites from Acacia cyanophylla","volume":"4","author":"Ghribia","year":"2014","journal-title":"Asian Pac. J. Trop. Biomed."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Prayogo, Y.H., Syafii, W., Sari, R.K., and Batubara, I. (2021). Pharmacological Activity and Phytochemical Profile of Acacia Heartwood Extracts. Sci. Pharm., 89.","DOI":"10.3390\/scipharm89030037"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1007\/s42452-021-04513-8","article-title":"Secondary metabolites, antibacterial and antioxidant properties of the leaf extracts of Acacia rigidula benth. and Acacia berlandieri benth","volume":"3","author":"Cavazos","year":"2021","journal-title":"SN Appl. Sci."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1080\/14786419.2014.947497","article-title":"Evaluation of antioxidant activities of the edible and medicinal Acacia albida organs related to phenolic compounds","volume":"29","author":"Karoune","year":"2015","journal-title":"Nat. Product Res."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Paula, V., Pedro, S.I., Campos, M.G., Delgado, T., Estevinho, L.M., and Anjos, O. (2022). Special Bioactivities of Phenolics from Acacia dealbata L. with Potential for Dementia, Diabetes and Antimicrobial Treatments. Appl. Sci., 12.","DOI":"10.3390\/app12031022"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1080\/14786419.2013.863200","article-title":"New cytotoxic spirostane saponin and biflavonoid glycoside from the leaves of Acacia saligna (Labill.) H.L. Wendl","volume":"28","author":"Gedara","year":"2014","journal-title":"Nat. Prod. Res."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.sajb.2011.09.001","article-title":"Activity of South African medicinal plants against Listeria monocytogenes biofilms, and isolation of active compounds from Acacia karroo","volume":"78","author":"Nyila","year":"2012","journal-title":"South Afr. J. Botany"},{"key":"ref_28","first-page":"35","article-title":"Antifilarial Effect of a Plant Acacia auriculiformis on Canine Dirofilariasis","volume":"37","author":"Chakraborty","year":"1995","journal-title":"Trop. Med."},{"key":"ref_29","first-page":"372","article-title":"Hydroethanolic leaf extract of Acacia auriculiformis exhibited antidiabetic and antioxidant activities","volume":"9","author":"Sharma","year":"2022","journal-title":"Egypt. J. Basic Appl. Sci."},{"key":"ref_30","first-page":"859","article-title":"Antioxidant and antimutagenic activities of Acacia pennatula pods","volume":"70","author":"Pacheco","year":"2011","journal-title":"J. Sci. Ind. Res."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"111","DOI":"10.14499\/indonesianjpharm27iss2pp111","article-title":"Cytotoxic and anti-viral activity of Acacia catechu on human peripheral blood mononuclear cells","volume":"27","author":"Gupta","year":"2016","journal-title":"Indones. J. Pharm."},{"key":"ref_32","first-page":"308","article-title":"Antibacterial and cytotoxic activities of Acacia aroma extracts","volume":"24","author":"Mattana","year":"2012","journal-title":"Emir. J. Food Agric."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0031-9422(97)00240-9","article-title":"Toxic amines and alkaloids from Acacia berlandieri","volume":"46","author":"Clement","year":"1997","journal-title":"Phytochemistry"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"5821","DOI":"10.1073\/pnas.101619098","article-title":"Avicins: Triterpenoid saponins from Acacia victoriae (Bentham) induce apoptosis by mitochondrial perturbation","volume":"98","author":"Haridas","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1007\/BF02864559","article-title":"Tannins from mimosoid legumes of Texas and Mexico","volume":"55","author":"Readel","year":"2001","journal-title":"Econ. Botany"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.fct.2009.01.009","article-title":"Antioxidant and anti-quorum sensing activities of green pod of Acacia nilotica L.","volume":"47","author":"Singh","year":"2009","journal-title":"Food Chem. Toxicol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.fct.2007.01.002","article-title":"Evaluation of antioxidant potential of ethyl acetate extract\/fractions of Acacia auriculiformis A","volume":"45","author":"Singh","year":"2007","journal-title":"Cunn. Food Chem. Toxicol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.foodchem.2009.11.022","article-title":"Umbelliferone\u2013an antioxidant isolated from Acacia nilotica (L.) Willd. Ex. Del","volume":"120","author":"Singh","year":"2010","journal-title":"Food Chem."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/0031-9422(79)83057-5","article-title":"Non-protein amino acids of Acacia species and their effect on the feeding of the acridids Anacridium melanorhodon and Locusta migratoria","volume":"18","author":"Evans","year":"1979","journal-title":"Phytochemistry"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1006\/jare.1995.0035","article-title":"Seasonal variation of two phenolic amines in Acacia berlandieri","volume":"30","author":"Forbes","year":"1995","journal-title":"J. Arid Environ."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1071\/CH9640160","article-title":"Alkaloids of the Australian Leguminosae. III. The occurrence of phenylethylamine derivatives in Acacia species","volume":"17","author":"Fitzgerald","year":"1964","journal-title":"Aust. J. Chem."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1071\/CH9650433","article-title":"Alkaloids of the Australian Leguminosae. V. The occurrence of methylated tryptamines in Acacia maidenii F. Muell","volume":"18","author":"Fitzgerald","year":"1965","journal-title":"Aust. J. Chem."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"588","DOI":"10.2307\/2666723","article-title":"Taxonomic revision of South American species of the genus Acacia subgenus Acacia (Fabaceae: Mimosoideae)","volume":"25","author":"Ebinger","year":"2000","journal-title":"Syst. Botany"},{"key":"ref_44","first-page":"315","article-title":"Comparative tanning ability of extracts from four North American species of Acacia","volume":"84","author":"Seigler","year":"1989","journal-title":"J. Am. Leather Chem. Assoc."},{"key":"ref_45","unstructured":"Maslin, B.R., Conn, E.E., and Dunn, J.E. (1987). Cyanogenic Australian Species of Acacia: A Preliminary Account of Their Toxicity Potential, Australian Centre for International Agricultural Research."},{"key":"ref_46","first-page":"645","article-title":"Cyanogenesis in the Leguminosae","volume":"29","author":"Seigler","year":"1989","journal-title":"Adv. Legume Biol. Monogr. Syst. Bot. Missouri Bot. Garden"},{"key":"ref_47","first-page":"79","article-title":"GC-MS analysis of chloroform extract of Acacia nilotica L. leaves","volume":"2","author":"Bai","year":"2014","journal-title":"J. Pharmacogn. Phytochem."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1055\/s-0028-1097801","article-title":"Chemical examination of Acacia modesta","volume":"27","author":"Josm","year":"1975","journal-title":"Planta Medica"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1007\/BF02540364","article-title":"Fatty acid composition of seeds from the Australian Acacia species","volume":"22","author":"Brown","year":"1987","journal-title":"Lipids"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"861","DOI":"10.3923\/ajps.2003.861.868","article-title":"Improving soil physical properties and its effect on Acacia tortilis seedlings growth under field conditions","volume":"2","author":"Mansour","year":"2003","journal-title":"Asian J. Plant Sci."},{"key":"ref_51","first-page":"23","article-title":"Studies of the Fats from Indigenous South African Plants. III:\u2206-9, 12-Hexadecadienoic Acid: Its Constitution and Occurrence in the Seed Fat and Seed Pod Fat of Acacia giraffae (Kameeldoorn)","volume":"5","author":"Harrison","year":"1952","journal-title":"J. South Afr. Chem. Inst."},{"key":"ref_52","first-page":"152","article-title":"Investigation of the seed oils of some Sudan Mimosaceae","volume":"64","author":"Grindley","year":"1945","journal-title":"J. Soc. Chem. Ind."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1007\/BF02640003","article-title":"Search for new industrial oils. I. Selected oils from 24 plant families","volume":"36","author":"Earle","year":"1959","journal-title":"J. Am. Oil Chem. Soc."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/0031-9422(88)83112-1","article-title":"Cyanogenesis in Australian species of Acacia","volume":"27","author":"Maslin","year":"1988","journal-title":"Phytochemistry"},{"key":"ref_55","first-page":"251","article-title":"A review on Acacia nilotica Linn. and its ethnobotany, phytochemical and pharmacological profile","volume":"4","author":"Vikrant","year":"2012","journal-title":"Int. J. Pharm. Res. Dev."},{"key":"ref_56","first-page":"109","article-title":"Economic potential from Western Australian Acacia species: Secondary plant products","volume":"4","author":"Seigler","year":"2002","journal-title":"Conserv. Sci. West. Aust."},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Bemiller, J.N., Whistler, R.L., Barkalow, D.G., and Chen, C.-C. (1993). Aloe, chia, flaxseed, okra, psyllium seed, quince seed, and tamarind gums. Industrial Gums, Elsevier.","DOI":"10.1016\/B978-0-08-092654-4.50013-9"},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Evert, R.F. (2006). Esau\u2019s Plant Anatomy: Meristems, Cells, and Tissues of the Plant Body: Their Structure, Function, and Development, John Wiley & Sons.","DOI":"10.1002\/0470047380"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/S0031-9422(00)80384-2","article-title":"The gum exudates from some Acacia subspecies of the series Botryocephalae","volume":"23","author":"Anderson","year":"1984","journal-title":"Phytochemistry"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/0305-1978(90)90086-U","article-title":"Acacia gum exudates from Somalia and Tanzania: The Acacia senegal complex","volume":"18","author":"Anderson","year":"1990","journal-title":"Biochem. Syst. Ecol."},{"key":"ref_61","unstructured":"Brockwell, J., Searle, S.D., Jeavons, A.C., and Waayers, M. (2005). Nitrogen fixation in acacias: An untapped resource for sustainable plantations, farm forestry and land reclamation, Australian Centre for International Agricultural Research. Monograph No. 115."},{"key":"ref_62","first-page":"6","article-title":"Etude Surle role des Acacia dans Le development rural au Burkin Faso et au Niger","volume":"1","author":"Guinko","year":"1991","journal-title":"Ouagaduogu (Mimeo)"},{"key":"ref_63","unstructured":"Whibley, D.J., and Symon, D.E. (1992). Acacias of South Australia, Flora and Fauna of South Australia Handbooks Committee, The University of Michigan."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ijbiomac.2005.12.015","article-title":"Solution properties of targacanthin (water-soluble part of gum tragacanth exudate from Astragalus gossypinus)","volume":"38","author":"Mohammadifar","year":"2006","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"Karamallah, K. (2000). Gum Arabic\u2013Quality and Quantity Assured. Gums and Stabilisers for the Food Industry 10, Elsevier.","DOI":"10.1533\/9781845698355.1.37"},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Al-Assaf, S., Phillips, G.O., and Amar, V. (2021). Gum ghatti. Handbook of Hydrocolloids, Elsevier.","DOI":"10.1016\/B978-0-12-820104-6.00012-7"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0268-005X(87)80020-6","article-title":"The composition of the proteinaceous gums exuded by Acacia gerrardii and Acacia goetzii subsp. goetzii","volume":"1","author":"Anderson","year":"1987","journal-title":"Food Hydrocoll."},{"key":"ref_68","first-page":"241","article-title":"Characterization and functional properties of some natural Acacia gums","volume":"17","author":"Daoub","year":"2018","journal-title":"J. Saudi Soc. Agric. Sci."},{"key":"ref_69","unstructured":"Younes, A. (2009). Physicochemical Studies on Some Acacia Gum Sand Their Fractions. [Ph.D. Thesis, Chemistry Department, Faculty of Science, Sudan University]."},{"key":"ref_70","unstructured":"Satti, A.A.E. (2011). Characterization and Toxicological Study of Acacia nilotica var. nilotica Gum from Sudan. [Ph.D. Thesis, Sudan University of Science and Technology]."},{"key":"ref_71","first-page":"11","article-title":"Characterization and simple fractionation of Acacia Senegal","volume":"2","author":"Ibrahim","year":"2013","journal-title":"J. Chem. Acta"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1016\/0031-9422(74)85105-8","article-title":"The composition and properties of gum exudates from subspecies of Acacia tortilis","volume":"13","author":"Anderson","year":"1974","journal-title":"Phytochemistry"},{"key":"ref_73","first-page":"100127","article-title":"Physicochemical and rheological properties of Acacia catechu exudate gum","volume":"2","author":"Sharma","year":"2021","journal-title":"Carbohydr. Polym. Technol. Appl."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0031-9422(00)84633-6","article-title":"Die freien aminos\u00e4uren in samen von mimosaceae","volume":"12","author":"Krauss","year":"1973","journal-title":"Phytochemistry"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0031-9422(00)82830-7","article-title":"N-acetyl-l-djenkolic acid, a novel amino acid isolated from Acacia farnesiana willd","volume":"1","author":"Gmelin","year":"1962","journal-title":"Phytochemistry"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1016\/S0031-9422(00)83025-3","article-title":"2-Amino-4-acetylaminobutyric acid, 2, 4-diaminobutyric acid and 2-amino-6N-oxalylureidopropionic acid (oxalylalbizziine) in seeds of Acacia angustissima","volume":"24","author":"Evans","year":"1985","journal-title":"Phytochemistry"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"10","DOI":"10.5962\/p.292490","article-title":"A review of the classification of Acacia (Leguminosae, Mimosoideae)","volume":"26","author":"Murphy","year":"2008","journal-title":"Muelleria"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.3891\/acta.chem.scand.15-1188","article-title":"Mimosaceen-Aminosauren. 7. Isolierung von Willardiin (3-(1-uracyl)-L-alanin) aus den samen von Acacia millefolia, Acacia lemmoni und mimosa asperata, munksgaard INT publ LTD 35 norre Sogade, Po BOX 2148, DK-1016 copenhagen","volume":"15","author":"Gmelin","year":"1961","journal-title":"Acta Chem. Scand."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1042\/bj0970794","article-title":"The origins of tannins and flavonoids in black-wattle barks and heartwoods, and their associatednon-tannin\u2019components","volume":"97","author":"Saayman","year":"1965","journal-title":"Biochem. J."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1071\/CH9721943c","article-title":"Phytochemical survey of the heartwood flavonoids of Acacia species from arid zones of Australia","volume":"25","author":"Porter","year":"1972","journal-title":"Aust. J. Chem."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/hlca.19690520104","article-title":"Sur les constituants odorants de l\u2019essence absolue de Cassie (Acacia farnesiana Willd.)","volume":"52","author":"Demole","year":"1969","journal-title":"Helvetica Chim. Acta"},{"key":"ref_82","unstructured":"Oyen, L., and Dung, N.X. (1999). Plant Resources of South-East Asia no. 19: Essential-Oil Plants, Backhuys Publishers."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1021\/jf00120a008","article-title":"Volatile components of Acacia sp. blossoms","volume":"31","author":"Flath","year":"1983","journal-title":"J. Agric. Food Chem."},{"key":"ref_84","unstructured":"Guenther, E. (1952). The Essential Oils, D. Van Nostrand Company."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1016\/0040-4020(79)85042-5","article-title":"Two novel cassane diterpenoids from Acacia jacquemontii","volume":"35","author":"Joshi","year":"1979","journal-title":"Tetrahedron"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"2991","DOI":"10.1016\/0031-9422(85)80042-X","article-title":"Labdane diterpenes from an Acacia species","volume":"24","author":"Forster","year":"1985","journal-title":"Phytochemistry"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S0031-9422(00)81888-9","article-title":"Structure of acacigenin-B, a novel triterpene ester isolated from Acacia concinna","volume":"18","author":"Anjaneyulu","year":"1979","journal-title":"Phytochemistry"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0031-9422(89)85039-3","article-title":"Structure of Acaciaside, a triterpenoid trisaccharide from Acacia auriculiformis","volume":"28","author":"Mahato","year":"1989","journal-title":"Phytochemistry"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1071\/CH9730839","article-title":"Extractives of Australian timbers. XIV. Triterpene glycosides of Acacia myrtifolia","volume":"26","author":"Eade","year":"1973","journal-title":"Aust. J. Chem."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"11557","DOI":"10.1073\/pnas.191363498","article-title":"Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), inhibit activation of nuclear factor-\u03baB by inhibiting both its nuclear localization and ability to bind DNA","volume":"98","author":"Haridas","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"11551","DOI":"10.1073\/pnas.191363198","article-title":"Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), suppress H-ras mutations and aneuploidy in a murine skin carcinogenesis model","volume":"98","author":"Hanausek","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1016\/S0031-9422(00)85959-2","article-title":"A phytochemical survey of the Australian species of Acacia","volume":"8","author":"Tindale","year":"1969","journal-title":"Phytochemistry"},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1016\/0031-9422(75)85306-4","article-title":"Flavonoids and tannins of Acacia species","volume":"14","author":"Malan","year":"1975","journal-title":"Phytochemistry"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/S0031-9422(00)86352-9","article-title":"Isomeric leucofisetinidins from Acacia mearnsii","volume":"8","author":"Drewes","year":"1969","journal-title":"Phytochemistry"},{"key":"ref_95","first-page":"299","article-title":"Phytochemical studies on the heart woods and barks of African and Australian species of Acacia","volume":"24","author":"Tindale","year":"1975","journal-title":"Boissiera"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1002\/jps.2600540216","article-title":"Phytochemical investigation of Acacia angustissima","volume":"54","author":"Hammer","year":"1965","journal-title":"J. Pharm. Sci."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"3767","DOI":"10.1016\/0031-9422(91)80106-B","article-title":"Polyphenols of Acacia raddiana","volume":"30","author":"Barakat","year":"1991","journal-title":"Phytochemistry"},{"key":"ref_98","first-page":"2483","article-title":"Metabolites from the purple heartwoods of the mimosoideae. Part 4. Acacia fasciculifera F. Muell ex. Benth: Fasciculiferin, fasciculiferol, and the synthesis of 7-aryl-and 7-flavanyl-peltogynoids","volume":"1","author":"Brandt","year":"1981","journal-title":"J. Chem. Soc. Perkin Transact."},{"key":"ref_99","doi-asserted-by":"crossref","unstructured":"Noreljaleel, A.E.M., and Wilhelm, A. (2020). Analysis of Commercial Proanthocyanidins. Part 6: Sulfitation of Flavan-3-Ols Catechin and Epicatechin, and Procyanidin B-3. Molecules, 25.","DOI":"10.3390\/molecules25214980"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"2883","DOI":"10.1016\/S0040-4020(01)88380-0","article-title":"Oligomeric flavanoids. part 14. Proguibourtinidins based on (-)-fisetinidol and (+)-epifisetinidol units","volume":"46","author":"Malan","year":"1990","journal-title":"Tetrahedron"},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/BF02985254","article-title":"Sources of tannin: Alternatives to wattle (Acacia mearnsii) among indigenous Kenyan species","volume":"46","author":"Mugedo","year":"1992","journal-title":"Econ. Botany"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1016\/S0031-9422(00)83054-X","article-title":"Biflavanoid proguibourtinidin carboxylic acids and their biflavanoid homologues from Acacia luederitzii","volume":"24","author":"Ferreira","year":"1985","journal-title":"Phytochemistry"},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1007\/BF01920127","article-title":"A new proanthocyanidin from the stem bark of Acacia suma","volume":"33","author":"Gandhi","year":"1977","journal-title":"Experientia"},{"key":"ref_104","doi-asserted-by":"crossref","unstructured":"Ferreira, D., van Rensburg, H., Malan, E., Coetzee, J., and Nel, R.J. (1999). Recent advances in the chemistry of proanthocyanidins. Phytochemicals in Human Health Protection, Nutrition, and Plant Defense, Springer.","DOI":"10.1007\/978-1-4615-4689-4_10"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/0031-9422(95)00440-I","article-title":"A (4\u03b2\u2192 5)-linked proteracacinidin dimer from the heartwood of Acacia caffra","volume":"40","author":"Malan","year":"1995","journal-title":"Phytochemistry"},{"key":"ref_106","unstructured":"Searle, S. (1991). The Rise and Demise of the Black Wattle Bark Industry in Australia, Division of Forestry and Forest Products, CSIRO."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1002\/pola.1986.080240503","article-title":"Stereochemistry and dynamic behavior of some synthetic angular profisetinidin tetraflavanoid derivatives","volume":"24","author":"Young","year":"1986","journal-title":"J. Polym. Sci. Part A Polym. Chem."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.jep.2011.09.019","article-title":"Gastrointestial and respiratory activities of Acacia leucophloea","volume":"138","author":"Imran","year":"2011","journal-title":"J. Ethnopharmacol."},{"key":"ref_109","first-page":"730","article-title":"Evaluation of the Antifungal Activity of the Potent Fraction of Hexane Extract Obtained from the bark of Acacia nilotica","volume":"3","author":"Rai","year":"2014","journal-title":"IJSR"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1021\/np030096l","article-title":"Natural products as sources of new drugs over the period 1981\u20132002","volume":"66","author":"Newman","year":"2003","journal-title":"J. Nat. Prod."},{"key":"ref_111","first-page":"627","article-title":"Anticancer and antimutagenic properties of Acacia nilotica (Linn.) on 7, 12-dimethylbenz (a) anthracene-induced skin papillomagenesis in Swiss albino mice","volume":"7","author":"Meena","year":"2006","journal-title":"Asian Pac. J. Cancer Prev."},{"key":"ref_112","first-page":"987692","article-title":"Protective effect of Acacia nilotica (L.) against acetaminophen-induced hepatocellular damage in wistar rats","volume":"2013","author":"Kannan","year":"2013","journal-title":"Adv. Pharmacol. Sci."},{"key":"ref_113","first-page":"1266","article-title":"Preliminary study on the desmutagenic and antimutagenic effect of some natural products","volume":"56","author":"Jain","year":"1987","journal-title":"Current Sci."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1177\/1534735412463818","article-title":"Human breast adenocarcinoma cytotoxicity and modulation of 7, 12-dimethylbenz [a] anthracene-induced mammary carcinoma in Balb\/c mice by Acacia catechu (Lf) Wild heartwood","volume":"12","author":"Monga","year":"2013","journal-title":"Integr. Cancer Ther."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"2575598","DOI":"10.1155\/2021\/2575598","article-title":"A Comprehensive Review on the Chemical Composition and Pharmacological Activities of Acacia catechu (Lf) Willd","volume":"2021","author":"Adhikari","year":"2021","journal-title":"J. Chem."},{"key":"ref_116","first-page":"1193","article-title":"Invasive Acacia nilotica a problematic weed is a source of potent methyl gallate","volume":"3","author":"Sharma","year":"2014","journal-title":"Int. J. Sci. Res."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1142\/S0192415X96000323","article-title":"Investigation of the anti-inflammatory activity of Acacia nilotica and Hibiscus sabdariffa","volume":"24","author":"Dafallah","year":"1996","journal-title":"Am. J. Chin. Med."},{"key":"ref_118","first-page":"55","article-title":"Antipyretic and analgesic activities of aqueous extract of Acacia nilotica root","volume":"26","author":"Alli","year":"2014","journal-title":"Biokemistri"},{"key":"ref_119","first-page":"835","article-title":"Evaluation of Acacia cyanophylla for their analgesic, anti-pyretic and anti-inflammatory potentials","volume":"35","author":"Iqbal","year":"2022","journal-title":"Pak. J. Pharm. Sci."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.jep.2010.01.057","article-title":"In vitro biological activities of niloticane, a new bioactive cassane diterpene from the bark of Acacia nilotica subsp. kraussiana","volume":"128","author":"Eldeen","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1055\/s-2003-38482","article-title":"Isolation and X-ray study of an anti-inflammatory active androstene steroid from Acacia nilotica","volume":"69","author":"Chaubal","year":"2003","journal-title":"Planta Medica"},{"key":"ref_122","first-page":"1","article-title":"Acute and chronic anti-inflammatory effects of the aqueous extract of Acacia nilotica (L.) Del.(Fabaceae) pods","volume":"1","author":"Sokeng","year":"2013","journal-title":"Acad. J. Med. Plants"},{"key":"ref_123","first-page":"1015","article-title":"Pharmacological evaluation of Acacia modesta bark for antipyretic, anti-inflammatory, analgesic, antidepressant and anticoagulant activities in Sprague Dawley rats","volume":"33","author":"Latif","year":"2020","journal-title":"Pak. J. Pharm. Sci."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3831\/KPI.2013.16.014","article-title":"In-vitro, anti-bacterial activities of aqueous extracts of Acacia catechu (LF) Willd, Castanea sativa, Ephedra sinica stapf and shilajita mumiyo against Gram positive and Gram negative bacteria","volume":"16","author":"Dashtdar","year":"2013","journal-title":"J. Pharmacopunct."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1080\/13880200802400527","article-title":"Antimicrobial screening and phytochemical analysis of the resin part of Acacia catechu","volume":"47","author":"Patel","year":"2009","journal-title":"Pharm. Biol."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"94","DOI":"10.3126\/jncs.v27i1.6667","article-title":"Antibacterial and antifungal activity of heartwood of Acacia catechu of Nepal","volume":"27","author":"Joshi","year":"2011","journal-title":"J. Nepal Chem. Soc."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"1","DOI":"10.31254\/jahm.2021.7101","article-title":"Solanum xanthocarpum and Acacia catechu Willd-an ayurvedic soothe: A randomized clinical trial","volume":"7","author":"Joshi","year":"2021","journal-title":"J. Ayurvedic Herb. Med."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"40","DOI":"10.3923\/ajaps.2020.40.59","article-title":"Chemical diversity and pharmacological properties of genus Acacia","volume":"13","author":"Amoussa","year":"2020","journal-title":"Asian J. Appl. Sci."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1139\/cjfr-2016-0499","article-title":"Physiological and biochemical characterization of Acacia stenophylla and Acacia albida exposed to salinity under hydroponic conditions","volume":"47","author":"Abbas","year":"2017","journal-title":"Can. J. For. Res."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.fct.2009.10.013","article-title":"Free radical scavenging activity from leaves of Acacia nilotica (L.) Wild. ex Delile, an Indian medicinal tree","volume":"48","author":"Kalaivani","year":"2010","journal-title":"Food Chem. Toxicol."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"5510099","DOI":"10.1155\/2021\/5510099","article-title":"Antidiabetic, antimicrobial, and molecular profiling of selected medicinal plants","volume":"2021","author":"Aryal","year":"2021","journal-title":"Evid.-Based Complement. Altern. Med."},{"key":"ref_132","doi-asserted-by":"crossref","unstructured":"Patil, A., and Modak, M. (2017). Comparative evaluation of oxidative stress modulating and DNA protective activities of aqueous and methanolic extracts of Acacia catechu. Medicines, 4.","DOI":"10.3390\/medicines4030065"},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"529","DOI":"10.2307\/4109654","article-title":"Chemotaxonomic Aspects of the Chemistry of Acacia Gum Exudates","volume":"32","author":"Anderson","year":"1978","journal-title":"Kew Bull."},{"key":"ref_134","first-page":"604","article-title":"Antifilarial effect of two triterpenoid saponins isolated from Acacia auriculiformis","volume":"31","author":"Ghosh","year":"1993","journal-title":"Indian J. Exp. Biol."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s12639-018-1064-1","article-title":"In-vitro and in silico efficacy of isolated alkaloid compounds from Rauvolfia tetraphylla L. against bovine filarial parasite Setaria cervi: A drug discovery approach","volume":"43","author":"Behera","year":"2019","journal-title":"J. Parasit. Dis."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1017\/S0022149X00015340","article-title":"Cestocidal activity of Acacia auriculiformis","volume":"70","author":"Ghosh","year":"1996","journal-title":"J. Helminthol."},{"key":"ref_137","first-page":"482","article-title":"In vivo antimalarial activity of ethanolic leaf extract of Acacia auriculiformis","volume":"2","author":"Okokon","year":"2010","journal-title":"Int. J. Drug. Dev. Res."},{"key":"ref_138","first-page":"167","article-title":"Letter to the editor: Hypoglycaemic activity of Acacia arabica, Acacia benthami and Acacia modesta leguminous seed diets in normal young albino rats","volume":"19","author":"Singh","year":"1975","journal-title":"Indian J. Physiol. Pharmacol."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40816-020-00179-8","article-title":"Evaluation of the alpha-amylase inhibitory activity of Nepalese medicinal plants used in the treatment of diabetes mellitus","volume":"6","author":"Khadayat","year":"2020","journal-title":"Clin. Phytosci."},{"key":"ref_140","first-page":"572013","article-title":"Antidiabetic activity of Acacia tortilis (Forsk.) Hayne ssp. raddiana polysaccharide on streptozotocin-nicotinamide induced diabetic rats","volume":"2014","author":"Singh","year":"2014","journal-title":"BioMed. Res. Int."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S1995-7645(11)60025-4","article-title":"Evaluation of antidiabetic and related actions of some Indian medicinal plants in diabetic rats","volume":"4","author":"Patil","year":"2011","journal-title":"Asian Pac. J. Trop. Med."},{"key":"ref_142","first-page":"489","article-title":"Inhibition of turnip mosaic virus by plant extracts","volume":"39","author":"Pandey","year":"1986","journal-title":"Indian Phytopathol."},{"key":"ref_143","first-page":"43","article-title":"Nemeticial and nematostatic response of aqueous extract of certain plants of semi-arid niche","volume":"6","author":"Sharma","year":"1995","journal-title":"Curr. Nematol."},{"key":"ref_144","first-page":"e00918","article-title":"Therapeutic potentials of Vachellia nilotica (L.) extracts in Hepatitis C infection: A review","volume":"13","author":"Ogwang","year":"2021","journal-title":"Sci. Afr."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1834-7819.2009.01180.x","article-title":"Short-term clinical effects of commercially available gel containing Acacia arabica: A randomized controlled clinical trial","volume":"55","author":"Pradeep","year":"2010","journal-title":"Aust. Dental J."},{"key":"ref_146","first-page":"1995","article-title":"A review on Acacia arabica\u2014An Indian medicinal plant","volume":"3","author":"Rajvaidhya","year":"2012","journal-title":"Int. J. Pharm. Sci. Res."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"17782","DOI":"10.1021\/acsomega.1c00302","article-title":"Manipulation of Gut Microbiota Using Acacia gum Polysaccharide","volume":"6","author":"Rawi","year":"2021","journal-title":"ACS Omega"},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.scp.2015.08.002","article-title":"Acacia nilotica (L.): A review of its traditional uses, phytochemistry, and pharmacology","volume":"2","author":"Rather","year":"2015","journal-title":"Sustain. Chem. Pharm."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1093\/nar\/gkab913","article-title":"NPCDR: Natural product-based drug combination and its disease-specific molecular regulation","volume":"50","author":"Sun","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1159\/000334488","article-title":"Interactions between Herbs and Conventional Drugs: Overview of the Clinical Data","volume":"21","author":"Izzo","year":"2012","journal-title":"Med. Princ. Pract."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1093\/jac\/dkh372","article-title":"Effect of gum arabic on the absorption of a single oral dose of amoxicillin in healthy Sudanese volunteers","volume":"54","author":"Eltayeb","year":"2004","journal-title":"J. Antimicrob. Chemother."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/S0254-6272(15)30144-8","article-title":"Pharmacokinetic interaction of Acacia catechu with CYP1A substrate theophylline in rabbits","volume":"35","author":"Raish","year":"2015","journal-title":"J. Tradit. Chin. Med."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/27\/21\/7340\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:05:15Z","timestamp":1760144715000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/27\/21\/7340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,28]]},"references-count":152,"journal-issue":{"issue":"21","published-online":{"date-parts":[[2022,11]]}},"alternative-id":["molecules27217340"],"URL":"https:\/\/doi.org\/10.3390\/molecules27217340","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,28]]}}}