{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T07:15:46Z","timestamp":1768893346016,"version":"3.49.0"},"reference-count":64,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T00:00:00Z","timestamp":1670803200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["19-13-00132-\u03a0"],"award-info":[{"award-number":["19-13-00132-\u03a0"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Three novel luminescent Eu(III) complexes, Eu1\u2013Eu3, have been synthesized and characterized with CHN analysis, mass-spectrometry and 1H NMR spectroscopy. The complexes display strong emission in dichloromethane solution upon excitation at 405 and 800 nm with a quantum yield from 18.3 to 31.6%, excited-state lifetimes in the range of 243\u20131016 ms at 20 \u00b0C, and lifetime temperature sensitivity of 0.9%\/K (Eu1), 1.9%\/K (Eu2), and 1.7%\/K (Eu3). The chromophores were embedded into biocompatible latex nanoparticles (NPs_Eu1\u2013NPs_Eu3) that prevented emission quenching and kept the photophysical characteristics of emitters unchanged with the highest temperature sensitivity of 1.3%\/K (NPs_Eu2). For this probe cytotoxicity, internalization dynamics and localization in CHO-K1 cells were studied together with lifetime vs. temperature calibration in aqueous solution, phosphate buffer, and in a mixture of growth media and fetal bovine serum. The obtained data were then averaged to give the calibration curve, which was further used for temperature estimation in biological samples. The probe was stable in physiological media and displayed good reproducibility in cycling experiments between 20 and 40 \u00b0C. PLIM experiments with thermostated CHO-K1 cells incubated with NPs_Eu2 indicated that the probe could be used for temperature estimation in cells including the assessment of temperature variations upon chemical shock (sample treatment with mitochondrial uncoupling reagent).<\/jats:p>","DOI":"10.3390\/molecules27248813","type":"journal-article","created":{"date-parts":[[2022,12,13]],"date-time":"2022-12-13T03:32:32Z","timestamp":1670902352000},"page":"8813","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Polymeric Nanoparticles with Embedded Eu(III) Complexes as Molecular Probes for Temperature Sensing"],"prefix":"10.3390","volume":"27","author":[{"given":"Kirill M.","family":"Kuznetsov","sequence":"first","affiliation":[{"name":"Department of General and Inorganic Chemistry, Institute of Chemistry, St. Petersburg State University, St. Petersburg 198504, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vadim A.","family":"Baigildin","sequence":"additional","affiliation":[{"name":"Department of General and Inorganic Chemistry, Institute of Chemistry, St. Petersburg State University, St. Petersburg 198504, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7169-1978","authenticated-orcid":false,"given":"Anastasia I.","family":"Solomatina","sequence":"additional","affiliation":[{"name":"Department of General and Inorganic Chemistry, Institute of Chemistry, St. Petersburg State University, St. Petersburg 198504, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekaterina E.","family":"Galenko","sequence":"additional","affiliation":[{"name":"Department of Organic Chemistry, Institute of Chemistry, St. Petersburg State University, St. Petersburg 198504, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6100-0309","authenticated-orcid":false,"given":"Alexander F.","family":"Khlebnikov","sequence":"additional","affiliation":[{"name":"Department of Organic Chemistry, Institute of Chemistry, St. Petersburg State University, St. Petersburg 198504, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor V.","family":"Sokolov","sequence":"additional","affiliation":[{"name":"Department of Organic Chemistry, Institute of Chemistry, St. Petersburg State University, St. Petersburg 198504, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergey P.","family":"Tunik","sequence":"additional","affiliation":[{"name":"Department of General and Inorganic Chemistry, Institute of Chemistry, St. Petersburg State University, St. Petersburg 198504, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia R.","family":"Shakirova","sequence":"additional","affiliation":[{"name":"Department of General and Inorganic Chemistry, Institute of Chemistry, St. Petersburg State University, St. Petersburg 198504, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4590","DOI":"10.1002\/smll.201600665","article-title":"Micro\/Nanoscale Thermometry for Cellular Thermal Sensing","volume":"12","author":"Bai","year":"2016","journal-title":"Small"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1600508","DOI":"10.1002\/adom.201600508","article-title":"In Vivo Luminescence Nanothermometry: From Materials to Applications","volume":"5","author":"Ximendes","year":"2017","journal-title":"Adv. Opt. Mater."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jphotochemrev.2016.12.001","article-title":"Thermometers for Monitoring Cellular Temperature","volume":"30","author":"Nakano","year":"2017","journal-title":"J. Photochem. Photobiol. C Photochem. Rev."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Drami\u0107anin, M. (2018). Luminescence: The Basics, Methods, and Instrumentation. Luminescence Thermometry, Elsevier.","DOI":"10.1016\/B978-0-08-102029-6.00003-8"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"040902","DOI":"10.1063\/5.0014825","article-title":"Trends in Luminescence Thermometry","volume":"128","year":"2020","journal-title":"J. Appl. Phys."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/cptc.201900255","article-title":"Latest Trends in Temperature Sensing by Molecular Probes","volume":"4","author":"Ogle","year":"2020","journal-title":"ChemPhotoChem"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"7834","DOI":"10.1039\/c3cs60102a","article-title":"Luminescent Probes and Sensors for Temperature","volume":"42","author":"Wang","year":"2013","journal-title":"Chem. Soc. Rev."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.trac.2018.03.003","article-title":"Organic Fluorescent Thermometers: Highlights from 2013 to 2017","volume":"102","author":"Qin","year":"2018","journal-title":"TrAC Trends Anal. Chem."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1007\/s00424-018-2113-4","article-title":"Intracellular Thermometry with Fluorescent Sensors for Thermal Biology","volume":"470","author":"Okabe","year":"2018","journal-title":"Pflug. Arch."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"3258","DOI":"10.1039\/D0QI00779J","article-title":"Thermo-Responsive Light-Emitting Metal Complexes and Related Materials","volume":"7","author":"Li","year":"2020","journal-title":"Inorg. Chem. Front."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1021\/acs.chemrev.7b00425","article-title":"Long-Lived Emissive Probes for Time-Resolved Photoluminescence Bioimaging and Biosensing","volume":"118","author":"Zhang","year":"2018","journal-title":"Chem. Rev."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"14782","DOI":"10.1002\/chem.201600860","article-title":"Lanthanide Organic Framework Luminescent Thermometers","volume":"22","author":"Rocha","year":"2016","journal-title":"Chem. Eur. J."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"100903","DOI":"10.1016\/j.mtchem.2022.100903","article-title":"Lanthanide and Transition Metals Doped Materials for Non-Contact Optical Thermometry with Promising Approaches","volume":"24","author":"Abbas","year":"2022","journal-title":"Mater. Today Chem."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"162494","DOI":"10.1016\/j.jallcom.2021.162494","article-title":"A Review and Outlook of Ratiometric Optical Thermometer Based on Thermally Coupled Levels and Non-Thermally Coupled Levels","volume":"894","author":"Wang","year":"2022","journal-title":"J. Alloys Compd."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"214040","DOI":"10.1016\/j.ccr.2021.214040","article-title":"Luminescent Lanthanide Nanocomposites in Thermometry: Chemistry of Dopant Ions and Host Matrices","volume":"444","author":"Ansari","year":"2021","journal-title":"Coord. Chem. Rev."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Drami\u0107anin, M. (2018). Biomedical Applications of Luminescence Thermometry. Luminescence Thermometry, Elsevier.","DOI":"10.1016\/B978-0-08-102029-6.00010-5"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"167535","DOI":"10.1016\/j.jallcom.2022.167535","article-title":"Multifunctional Rare Earth Ions-Doped Ba2LaF7 Nanocrystals for Simultaneous Temperature Sensing and Photothermal Therapy","volume":"931","author":"Li","year":"2023","journal-title":"J. Alloys Compd."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.jallcom.2018.03.002","article-title":"Luminescent Nanothermometry Using Short-Wavelength Infrared Light","volume":"746","author":"Savchuk","year":"2018","journal-title":"J. Alloys Compd."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"4812","DOI":"10.1364\/OL.42.004812","article-title":"Nanometer-Scale Luminescent Thermometry in Bovine Embryos","volume":"42","author":"Alkahtani","year":"2017","journal-title":"Opt. Lett."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"4799","DOI":"10.1039\/c2nr30663h","article-title":"Thermometry at the Nanoscale","volume":"4","author":"Brites","year":"2012","journal-title":"Nanoscale"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Bustamante, N., Ielasi, G., Bedoya, M., and Orellana, G. (2018). Optimization of Temperature Sensing with Polymer-Embedded Luminescent Ru(II) Complexes. Polymers, 10.","DOI":"10.3390\/polym10030234"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.jcis.2016.09.059","article-title":"Development of Fluorescent Thermoresponsive Nanoparticles for Temperature Monitoring on Membrane Surfaces","volume":"486","author":"Santoro","year":"2017","journal-title":"J. Colloid Interface Sci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"10857","DOI":"10.1002\/chem.200901511","article-title":"Red- and Green-Emitting Iridium(III) Complexes for a Dual Barometric and Temperature-Sensitive Paint","volume":"15","author":"Fischer","year":"2009","journal-title":"Chem. Eur. J."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"15706","DOI":"10.1002\/chem.201201358","article-title":"Referenced Dual Pressure- and Temperature-Sensitive Paint for Digital Color Camera Read Out","volume":"18","author":"Fischer","year":"2012","journal-title":"Chem. Eur. J."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"9623","DOI":"10.1039\/c2dt30835e","article-title":"Oxygen and Temperature Sensitivity of Blue to Green to Yellow Light-Emitting Pt(II) Complexes","volume":"41","author":"Karakus","year":"2012","journal-title":"Dalton Trans."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"18541","DOI":"10.1039\/C8NJ04489A","article-title":"A Highly Sensitive Luminescent Ratiometric Thermometer Based on Europium(III) and Terbium(III) Benzoylacetonate Complexes Chemically Bonded to Ethyldiphenylphosphine Oxide Functionalized Polydimethylsiloxane","volume":"42","author":"Mazali","year":"2018","journal-title":"New J. Chem."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3184\/003685005783238435","article-title":"Making Sense of Lanthanide Luminescence","volume":"88","author":"Werts","year":"2005","journal-title":"Sci. Prog."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"10269","DOI":"10.1021\/ic8012975","article-title":"Design of Dipicolinic Acid Ligands for the Two-Photon Sensitized Luminescence of Europium Complexes with Optimized Cross-Sections","volume":"47","author":"Picot","year":"2008","journal-title":"Inorg. Chem."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Drami\u0107anin, M. (2018). Lanthanide and Transition Metal Ion Doped Materials for Luminescence Temperature Sensing. Luminescence Thermometry, Elsevier.","DOI":"10.1016\/B978-0-08-102029-6.00006-3"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Cotton, S. (2006). Electronic and Magnetic Properties of the Lanthanides. Lanthanide and Actinide Chemistry, John Wiley & Sons, Ltd.","DOI":"10.1002\/0470010088.ch5"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1021\/acsapm.9b00952","article-title":"Eu-Based Phosphorescence Lifetime Polymer Nanothermometer: A Nanoemulsion Polymerization Approach to Eliminate Quenching of Eu Emission in Aqueous Media","volume":"2","author":"Shakirova","year":"2020","journal-title":"ACS Appl. Polym. Mater."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"3524","DOI":"10.1021\/acs.joc.9b00115","article-title":"Isoxazole Strategy for the Synthesis of 2,2\u2032-Bipyridine Ligands: Symmetrical and Unsymmetrical 6,6\u2032-Binicotinates, 2,2\u2032-Bipyridine-5-Carboxylates, and Their Metal Complexes","volume":"84","author":"Galenko","year":"2019","journal-title":"J. Org. Chem."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1021\/ac9020825","article-title":"Luminescence Switching by Hybridization-Directed Mixed Lanthanide Complex Formation","volume":"82","author":"Karhunen","year":"2010","journal-title":"Anal. Chem."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"5309","DOI":"10.1021\/ic102465j","article-title":"Impressive Europium Red Emission Induced by Two-Photon Excitation for Biological Applications","volume":"50","author":"Lo","year":"2011","journal-title":"Inorg. Chem."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1080\/00268977000100171","article-title":"The Energy Gap Law for Radiationless Transitions in Large Molecules","volume":"18","author":"Englman","year":"1970","journal-title":"Mol. Phys."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1039\/D1DT03077A","article-title":"Phosphorescent NIR Emitters for Biomedicine: Applications, Advances and Challenges","volume":"51","author":"Chelushkin","year":"2022","journal-title":"Dalton Trans."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1080\/01932691.2016.1262778","article-title":"Methyl Methacrylate Particles with Amino Groups on the Surface: Colloid Stability and Sorption of Biologically Active Substances","volume":"38","author":"Baigildin","year":"2017","journal-title":"J. Dispers. Sci. Technol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"10694","DOI":"10.1039\/D0CC04459H","article-title":"Lifetime-Based Nanothermometry in Vivo with Ultra-Long-Lived Luminescence","volume":"56","author":"Su","year":"2020","journal-title":"Chem. Commun."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1039\/C9NH00693A","article-title":"A Simple yet Effective AIE-Based Fluorescent Nano-Thermometer for Temperature Mapping in Living Cells Using Fluorescence Lifetime Imaging Microscopy","volume":"5","author":"Gao","year":"2020","journal-title":"Nanoscale Horiz."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"15072","DOI":"10.1021\/acs.analchem.1c03092","article-title":"Sensitive and Stable Thermometer Based on the Long Fluorescence Lifetime of Au Nanoclusters for Mitochondria","volume":"93","author":"Wang","year":"2021","journal-title":"Anal. Chem."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"4458","DOI":"10.1039\/C5CC09943A","article-title":"Direct Organelle Thermometry with Fluorescence Lifetime Imaging Microscopy in Single Myotubes","volume":"52","author":"Itoh","year":"2016","journal-title":"Chem. Commun."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1088\/0957-4484\/14\/8\/304","article-title":"Nanoscale Thermometry via the Fluorescence of YAG:Ce Phosphor Particles: Measurements from 7 to 77 \u00b0C","volume":"14","author":"Allison","year":"2003","journal-title":"Nanotechnology"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"3643","DOI":"10.1002\/chem.200601580","article-title":"An Optical Thermometer Based on the Delayed Fluorescence of C70","volume":"13","author":"Nagl","year":"2007","journal-title":"Chem. Eur. J."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1002\/adma.200901614","article-title":"Luminescent Europium(III) Nanoparticles for Sensing and Imaging of Temperature in the Physiological Range","volume":"22","author":"Peng","year":"2010","journal-title":"Adv. Mater."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"11154","DOI":"10.1002\/anie.201306366","article-title":"Intracellular Thermometry by Using Fluorescent Gold Nanoclusters","volume":"52","author":"Shang","year":"2013","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1038\/ncomms1714","article-title":"Intracellular Temperature Mapping with a Fluorescent Polymeric Thermometer and Fluorescence Lifetime Imaging Microscopy","volume":"3","author":"Okabe","year":"2012","journal-title":"Nat. Commun."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"5397","DOI":"10.1039\/D0CS01127D","article-title":"Understanding Nanoparticle Endocytosis to Improve Targeting Strategies in Nanomedicine","volume":"50","author":"Susnik","year":"2021","journal-title":"Chem. Soc. Rev."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Hayashi, T., Fukuda, N., Uchiyama, S., and Inada, N. (2015). A Cell-Permeable Fluorescent Polymeric Thermometer for Intracellular Temperature Mapping in Mammalian Cell Lines. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0117677"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1093\/oxfordjournals.jbchem.a132117","article-title":"Calorimetric Studies of Heat of Respiration of Mitochondria","volume":"84","author":"Nakamura","year":"1978","journal-title":"J. Biochem."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.1021\/ja807714j","article-title":"Hydrophilic Fluorescent Nanogel Thermometer for Intracellular Thermometry","volume":"131","author":"Gota","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"12889","DOI":"10.1038\/s41598-017-12634-7","article-title":"Difference in Intracellular Temperature Rise between Matured and Precursor Brown Adipocytes in Response to Uncoupler and \u03b2-Adrenergic Agonist Stimuli","volume":"7","author":"Tsuji","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1038\/nmeth.2690","article-title":"Genetically Encoded Fluorescent Thermosensors Visualize Subcellular Thermoregulation in Living Cells","volume":"10","author":"Kiyonaka","year":"2013","journal-title":"Nat. Methods"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"5878","DOI":"10.1016\/j.bmcl.2013.08.091","article-title":"Triphenylphosphonium Salts of 1,2,4-Benzothiadiazine 1,1-Dioxides Related to Diazoxide Targeting Mitochondrial ATP-Sensitive Potassium Channels","volume":"23","author":"Charif","year":"2013","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"4656","DOI":"10.1021\/acsabm.9b00739","article-title":"Mitochondria-Targeting Thermosensitive Initiator with Enhanced Anticancer Efficiency","volume":"2","author":"Peng","year":"2019","journal-title":"ACS Appl. Bio Mater."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Chr\u00e9tien, D., B\u00e9nit, P., Ha, H.-H., Keipert, S., El-Khoury, R., Chang, Y.-T., Jastroch, M., Jacobs, H.T., Rustin, P., and Rak, M. (2018). Mitochondria Are Physiologically Maintained at Close to 50 \u00b0C. PLoS Biol., 16.","DOI":"10.1371\/journal.pbio.2003992"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"16061","DOI":"10.1002\/chem.201201437","article-title":"Synthesis and Characterization of Reversible Chemosensory Polymers: Modulation of Sensitivity through the Attachment of Novel Imidazole Pendants","volume":"18","author":"Satapathy","year":"2012","journal-title":"Chem. Eur. J."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1002\/zaac.200600154","article-title":"Direct Oxidation of Europium Metal with Acetic Acid: Anhydrous Europium(III) Acetate, Eu(OAc)3, Its Sesqui-Hydrate, Eu(OAc)3(H2O)1.5, and the \u201cHydrogendiacetate\u201d, [Eu(H(OAc)2)3](H2O)","volume":"632","author":"Pantenburg","year":"2006","journal-title":"Z. Anorg. Allg. Chem."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"3543","DOI":"10.1016\/j.ica.2007.04.049","article-title":"Adducts of Europium \u03b2-Diketonates with Nitrogen p,P\u2032-Disubstituted Bipyridine and Phenanthroline Ligands: Synthesis, Structural Characterization, and Luminescence Studies","volume":"360","author":"Maeyer","year":"2007","journal-title":"Inorg. Chim. Acta"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1002\/cmdc.201800088","article-title":"Tuning the Hydrophobicity of a Mitochondria-Targeted NO Photodonor","volume":"13","author":"Sodano","year":"2018","journal-title":"ChemMedChem"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1163\/156856205774269539","article-title":"Development of Amine-Containing Polymeric Particles","volume":"16","author":"Tauro","year":"2005","journal-title":"J. Biomater. Sci. Polym. Ed."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1351\/PAC-REP-10-09-31","article-title":"Standards for Photoluminescence Quantum Yield Measurements in Solution (IUPAC Technical Report)","volume":"83","author":"Brouwer","year":"2011","journal-title":"Pure Appl. Chem."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1351\/pac-rep-12-03-03","article-title":"Determination of the Photoluminescence Quantum Yield of Dilute Dye Solutions (IUPAC Technical Report)","volume":"85","author":"Rurack","year":"2013","journal-title":"Pure Appl. Chem."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"062029","DOI":"10.1088\/1742-6596\/917\/6\/062029","article-title":"Two-Photon Absorption Cross Section for Coumarins 102, 153 and 307","volume":"917","author":"Melnikov","year":"2017","journal-title":"J. Phys. Conf. Ser."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s10895-005-0054-8","article-title":"Absolute Measurements of Photoluminescence Quantum Yields of Solutions Using an Integrating Sphere","volume":"16","author":"Holland","year":"2006","journal-title":"J. Fluoresc."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/27\/24\/8813\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:39:53Z","timestamp":1760146793000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/27\/24\/8813"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,12]]},"references-count":64,"journal-issue":{"issue":"24","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["molecules27248813"],"URL":"https:\/\/doi.org\/10.3390\/molecules27248813","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,12]]}}}