{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:52:05Z","timestamp":1787161925284,"version":"build-2736575974"},"reference-count":25,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T00:00:00Z","timestamp":1675123200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Deputy-Ministry of Agriculture, Ministry of Environment, Water and Agriculture, Kingdom of Saudi Arabia"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>In recent years, there has been a significant increase related to pesticide residues in foods, which may increase the risks to the consumer of these foods with the different quality and concentrations of pesticide residues. Pesticides are used for controlling pests that reduce yields. On the other hand, it has become a major public health concern due to its toxic properties. Thus, the objective of the current study employed the application of Quick Easy Cheap Effective Rugged Safe (QuEChERS) method, in combination with gas and liquid chromatography-tandem mass spectrometric detection (GCMSMS, LCMSMS) in order to determine 137 pesticide residues (63 insecticides, 41 acaricides, 40 herbicide, 55 fungicide, nematicide, growth regulator, Chitin synthesis inhibitors, and Juvenile hormone mimics), in 801 vegetables such as 139 tomatoes, 185 peppers, 217 squash, 94 eggplants, and 166 cucumbers from different locations in Hail and Riyadh cities. The results showed that the majority of pesticide residues were detected for each of the following pesticides: acetaimpride, metalaxyl, imidaclopride, bifenthrin, pyridaben, difenoconazole, and azoxystrobien, which were repeated in the samples studied 39, 21, 11, 10, 8, 7, and 5, respectively. In addition, results observed that the tomato was the most contaminated with pesticide residues; it was contaminated with 19 compounds and was followed by pepper, cucumber, and squash, and the last commodity in the contaminated ranking was eggplant. The highest calculated estimated daily intakes (EDIs) were recorded for tomatoes which were estimated between 0.013 to 0.516 mg\/kg of body weight per day (bw\/day) while the lowest EDIs value was between 0.000002 to 0.0005 mg\/kg of bw\/day for cucumber. Results indicated that the EDIs values were lower than the acceptable daily intake (ADI) values. Results observed that the most of pesticide residues exposure in food consumption in Saudi Arabia were lower than ADIs. In addition, the highest value for health risk index (HRI) was recorded with Ethion residue in tomato, but in sweet pepper, the highest value for HRI was 127.5 in the form of fipronil residue. On the other hand, results found that the highest values of HRI were 1.54, 1.61, and 0.047 for difenoconazole, bifenthrin, and pyridaben residues in squash, eggplant, and cucumber.<\/jats:p>","DOI":"10.3390\/molecules28031343","type":"journal-article","created":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T01:36:59Z","timestamp":1675215419000},"page":"1343","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Risk Assessment of Pesticide Residues by GC-MSMS and UPLC-MSMS in Edible Vegetables"],"prefix":"10.3390","volume":"28","author":[{"given":"Mohamed T.","family":"Selim","sequence":"first","affiliation":[{"name":"Institute of Research and Consultancy, Ministry of Environment, Water and Agriculture, Riyadh 11442, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad M.","family":"Almutari","sequence":"additional","affiliation":[{"name":"National Agriculture & Animal Resources Research Center, Riyadh 11442, Saudi Arabia"},{"name":"Plant Resource, Ministry of Environment, Water and Agriculture, Riyadh 11442, Saudi Arabia"},{"name":"Food and Environmental Research Center in Unayzah, Ministry of Municipal and Rural Affairs, Unayzah 51911, Al-Qassim, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan I.","family":"Shehab","sequence":"additional","affiliation":[{"name":"Food and Environmental Research Center in Unayzah, Ministry of Municipal and Rural Affairs, Unayzah 51911, Al-Qassim, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9341-711X","authenticated-orcid":false,"given":"Mohamed H.","family":"EL-Saeid","sequence":"additional","affiliation":[{"name":"Chromatographic Analysis Unit, Soil Science Department, College of Food & Agricultural Sciences, King Saud University, P.O. Box 2460, Riyadh 11451, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1016\/j.foodcont.2011.01.007","article-title":"Evaluation of pesticide residues in fruits and vegetables from Xiamen, China","volume":"22","author":"Chen","year":"2011","journal-title":"Food Control"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.foodcont.2010.09.037","article-title":"Exposure of several Belgian consumer groups to pesticide residues through fresh fruit and vegetable consumption","volume":"22","author":"Claeys","year":"2011","journal-title":"Food Control"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/s13765-012-2101-x","article-title":"Residual pattern of acequinocyl and hydroxyl acequinocyl in perilla leaf grown under greenhouse conditions using ultra performance liquid chromatography\u2013photo diode array detector with tandem mass confirmation","volume":"55","author":"Na","year":"2012","journal-title":"J. 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