{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T08:27:22Z","timestamp":1785486442338,"version":"3.56.0"},"reference-count":97,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2023,3,5]],"date-time":"2023-03-05T00:00:00Z","timestamp":1677974400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Wroc\u0142aw University of Environmental and Life Sciences","award":["SR\/FIST\/LS-1\/2019\/522"],"award-info":[{"award-number":["SR\/FIST\/LS-1\/2019\/522"]}]},{"name":"Department of Science and Technology (DST-FIST), India","award":["SR\/FIST\/LS-1\/2019\/522"],"award-info":[{"award-number":["SR\/FIST\/LS-1\/2019\/522"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Mosquitoes are the potential vectors of several viral diseases such as filariasis, malaria, dengue, yellow fever, Zika fever and encephalitis in humans as well as other species. Dengue, the most common mosquito-borne disease in humans caused by the dengue virus is transmitted by the vector Ae. aegypti. Fever, chills, nausea and neurological disorders are the frequent symptoms of Zika and dengue. Thanks to various anthropogenic activities such as deforestation, industrialized farming and poor drainage facilities there has been a significant rise in mosquitoes and vector-borne diseases. Control measures such as the destruction of mosquito breeding places, a reduction in global warming, as well as the use of natural and chemical repellents, mainly DEET, picaridin, temephos and IR-3535 have proven to be effective in many instances. Although potent, these chemicals cause swelling, rashes, and eye irritation in adults and children, and are also toxic to the skin and nervous system. Due to their shorter protection period and harmful nature towards non-target organisms, the use of chemical repellents is greatly reduced, and more research and development is taking place in the field of plant-derived repellents, which are found to be selective, biodegradable and harmless to non-target species. Many tribal and rural communities across the world have been using plant-based extracts since ancient times for various traditional and medical purposes, and to ward off mosquitoes and various other insects. In this regard, new species of plants are being identified through ethnobotanical surveys and tested for their repellency against Ae. aegypti. This review aims to provide insight into many such plant extracts, essential oils and their metabolites, which have been tested for their mosquitocidal activity against different life cycle forms of Ae. Aegypti, as well as for their efficacy in controlling mosquitoes.<\/jats:p>","DOI":"10.3390\/molecules28052386","type":"journal-article","created":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T02:06:43Z","timestamp":1678068403000},"page":"2386","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Bioactive Molecules Derived from Plants in Managing Dengue Vector Aedes aegypti (Linn.)"],"prefix":"10.3390","volume":"28","author":[{"given":"Sridhar Shanmuga","family":"Priya","sequence":"first","affiliation":[{"name":"Department of Biotechnology, St. Peter\u2019s Institute of Higher Education Research, Chennai 600077, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabhakaran","family":"Vasantha-Srinivasan","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics, Saveetha School of Engineering, Saveetha Institute of Medical 17 and Technical Sciences (SIMATS), Chennai 602105, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ammar B.","family":"Altemimi","sequence":"additional","affiliation":[{"name":"Department of Food Science, College of Agriculture, University of Basrah, Basrah 61004, Iraq"},{"name":"College of Medicine, University of Warith Al-Anbiyaa, Karbala 56001, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramji","family":"Keerthana","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, RV College of Engineering, Bangalore 560059, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5259-761X","authenticated-orcid":false,"given":"Narayanaswamy","family":"Radhakrishnan","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 602105, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0839-2021","authenticated-orcid":false,"given":"Sengottayan","family":"Senthil-Nathan","sequence":"additional","affiliation":[{"name":"Division of Bio-Pesticides and Environmental Toxicology, Sri Paramakalyani Centre for 14 Excellence in Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, 15, Tirunelveli 627412, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kandasamy","family":"Kalaivani","sequence":"additional","affiliation":[{"name":"Post Graduate and Research Centre, Department of Zoology, Sri Parasakthi College for Women, Courtrallam 627802, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nainarpandian","family":"Chandrasekar","sequence":"additional","affiliation":[{"name":"Centre for Geo\u2013Technology, Manonmaniam Sundaranar University, Tirunelveli 627012, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sengodan","family":"Karthi","sequence":"additional","affiliation":[{"name":"Department of Entomology, College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40503, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3060-6217","authenticated-orcid":false,"given":"Raja","family":"Ganesan","sequence":"additional","affiliation":[{"name":"Institute for Liver and Digestive Diseases, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zina T.","family":"Alkanan","sequence":"additional","affiliation":[{"name":"Department of Food Science, College of Agriculture, University of Basrah, Basrah 61004, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4344-0351","authenticated-orcid":false,"given":"Tarun","family":"Pal","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, Vignan\u2019s Foundation for Science, Technology and Research, Vadlamudi, Guntur 522213, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9621-8917","authenticated-orcid":false,"given":"Om Prakash","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Engineering, Jacob Institute of Biotechnology and Bioengineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj 211007, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4100-3438","authenticated-orcid":false,"given":"Jaros\u0142aw","family":"Pro\u0107k\u00f3w","sequence":"additional","affiliation":[{"name":"Department of Plant Biology, Institute of Environmental Biology, Wroc\u0142aw University of Environmental and Life Sciences, Ko\u017cuchowska 5b, 51-631 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.actatropica.2016.07.009","article-title":"Anti-dengue efficacy of bioactive andrographolide from Andrographis paniculata (Lamiales: Acanthaceae) against the primary dengue vector Aedes aegypti (Diptera: Culicidae)","volume":"163","author":"Edwin","year":"2016","journal-title":"Acta Trop."},{"key":"ref_2","first-page":"13","article-title":"Mosquito control by larvivorous fish","volume":"127","author":"Chandra","year":"2008","journal-title":"Indian J. Med. Res."},{"key":"ref_3","unstructured":"World Health Organisation (2022, May 16). \u201cWorld Health Day 2014: Preventing Vector-Borne Diseases\u201d. Available online: https:\/\/www.who.int\/news\/item\/02-04-2014-world-health-day-2014-preventing-vector-borne-diseases."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1128\/MMBR.64.1.115-137.2000","article-title":"Genetics of mosquito vector competence","volume":"64","author":"Beerntsen","year":"2000","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.4049\/jimmunol.166.2.1057","article-title":"Bispecific monoclonal antibodies mediate binding of dengue virus to erythrocytes in a monkey model of passive viremia","volume":"166","author":"Hahn","year":"2001","journal-title":"J. Immunol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1146\/annurev.ento.45.1.371","article-title":"Insecticide resistance in insect vectors of human disease","volume":"45","author":"Hemingway","year":"2000","journal-title":"Annu. Rev. Entomol."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Amala, K., Karthi, S., Ganesan, R., Radhakrishnan, N., Srinivasan, K., Mostafa, A.E.Z.M., Al-Ghamdi, A.A., Alkahtani, J., Elshikh, M.S., and Senthil-Nathan, S. (2012). Bioefficacy of Epaltes divaricata (L.) n-Hexane extracts and their major metabolites against the Lepidopteran pests Spodoptera litura (fab.) and dengue mosquito Aedes aegypti (Linn.). Molecules, 26.","DOI":"10.3390\/molecules26123695"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"113711","DOI":"10.1016\/j.envres.2022.113711","article-title":"Green synthesis of gold nanoparticles using Gracilaria crassa leaf extract and their ecotoxicological potential: Issues to be considered","volume":"213","author":"Kamaraj","year":"2022","journal-title":"Environ. Res."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1038\/nature12060","article-title":"The global distribution and burden of dengue","volume":"496","author":"Bhatt","year":"2013","journal-title":"Nature"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1136\/bmj.324.7353.1563","article-title":"Dengue: An escalating problem","volume":"324","author":"Gibbons","year":"2002","journal-title":"BMJ"},{"key":"ref_11","unstructured":"WHO (2022, May 16). Trade, Foreign Policy, Diplomacy and Health: Public\u2013Private Partnerships for Health. Available online: http:\/\/www.who.int\/trade\/glossary\/story077\/en\/."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"105474","DOI":"10.1016\/j.aquatox.2020.105474","article-title":"Toxicological screening of marine red algae Champia parvula (C. Agardh) against the dengue mosquito vector Aedes aegypti (Linn.) and its non-toxicity against three beneficial aquatic predators","volume":"222","author":"Yogarajalakshmi","year":"2020","journal-title":"Aquat. Toxicol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.pt.2014.04.002","article-title":"Boosting the sterile insect technique to control mosquitoes","volume":"30","author":"Bouyer","year":"2014","journal-title":"Trends Parasitol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1093\/jisesa\/iev125","article-title":"The Efficacy of Some Commercially Available Insect Repellents for Aedes aegypti (Diptera: Culicidae) and Aedes albopictus (Diptera: Culicidae)","volume":"15","author":"Rodriguez","year":"2015","journal-title":"J. Insect Sci."},{"key":"ref_15","first-page":"CD008090","article-title":"Larvivorous fish for preventing malaria transmission","volume":"12","author":"Walshe","year":"2017","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1046\/j.1472-4642.2003.00013.x","article-title":"Alien predators and amphibian declines: Review of two decades of science and the transition to conservation","volume":"9","author":"Kats","year":"2003","journal-title":"Divers. Distrib."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"467","DOI":"10.4269\/ajtmh.2007.77.467","article-title":"Insecticide Resistance Mechanisms of Brazilian Aedes aegypti Populations from 2001 to 2004","volume":"77","author":"Montella","year":"2007","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"171756","DOI":"10.1155\/2015\/171756","article-title":"The Role of Flavonoids on Oxidative Stress in Epilepsy","volume":"2015","author":"Diniz","year":"2015","journal-title":"Oxid. Med. Cell. Longev."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.pt.2010.08.004","article-title":"Pyrethroid resistance in African anopheline mosquitoes: What are the implications for malaria control?","volume":"27","author":"Ranson","year":"2011","journal-title":"Trends Parasitol."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Marcombe, S., Mathieu, R.B., Pocquet, N., Riaz, M.-A., Poupardin, R., S\u00e9lior, S., Darriet, F., Reynaud, S., Y\u00e9bakima, A., and Corbel, V. (2012). Insecticide Resistance in the Dengue Vector Aedes aegypti from Martinique: Distribution, Mechanisms and Relations with Environmental Factors. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0030989"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1641\/0006-3568(2001)051[0980:SPATLH]2.0.CO;2","article-title":"\u201cSelective\u201d Pesticides: Are They Less Hazardous to the Environment?","volume":"51","author":"Stark","year":"2001","journal-title":"BioScience"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.yrtph.2009.09.004","article-title":"Adverse events associated with the use of insect repellents containing N,N-diethyl-m-toluamide (DEET)","volume":"56","author":"Osimitz","year":"2010","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1186\/1756-3305-7-173","article-title":"Assessment of methods used to determine the safety of the topical insect repellent N,N-diethyl-m-toluamide (DEET)","volume":"7","author":"Behrens","year":"2014","journal-title":"Parasites Vectors"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/0973-7847.95849","article-title":"Historical review of medicinal plants\u2019 usage","volume":"6","author":"Petrovska","year":"2012","journal-title":"Pharmacogn. Rev."},{"key":"ref_25","first-page":"1718","article-title":"Neuropharmacological studies of Piper auritum Kunth (Piperaceae): Antinociceptive and anxiolytic-like effects","volume":"7","author":"Rosa","year":"2013","journal-title":"J. Med. Plant Res."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3109\/13880209.2011.619700","article-title":"An ethnobotanical survey of medicinal plants of Laos toward the discovery of bioactive compounds as potential candidates for pharmaceutical development","volume":"50","author":"Soejarto","year":"2011","journal-title":"Pharm. Biol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"13","DOI":"10.5530\/srp.2017.1.4","article-title":"Plant Flavonoids as Potential Source of Future Antimalarial leads","volume":"8","author":"Rudrapal","year":"2016","journal-title":"Syst. Rev. Pharm."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Morrison, A.C., Zielinski-Gutierrez, E., Scott, T.W., and Rosenberg, R. (2008). Defining Challenges and Proposing Solutions for Control of the Virus Vector Aedes aegypti. PLoS Med., 5.","DOI":"10.1371\/journal.pmed.0050068"},{"key":"ref_29","unstructured":"(2022, September 24). Aedes Mosquito Genus. Available online: https:\/\/www.britannica.com\/animal\/Aedes."},{"key":"ref_30","unstructured":"(2022, September 24). Mosquito Life Cycle Aedes aegypti, Available online: https:\/\/www.cdc.gov\/dengue\/resources\/factsheets\/mosquitolifecyclefinal.pdf."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Shepard, D.S., Undurraga, E.A., and Halasa, Y.A. (2013). Economic and Disease Burden of Dengue in Southeast Asia. PLOS Neglected Trop. Dis., 7.","DOI":"10.1371\/journal.pntd.0002055"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1128\/CMR.11.3.480","article-title":"Dengue and Dengue Hemorrhagic Fever","volume":"11","author":"Gubler","year":"1998","journal-title":"Clin. Microbiol. Rev."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1002\/pbc.23229","article-title":"Dengue Fever in Patients with Pediatric Malignancy on Chemotherapy: A Concern in Tropical Countries","volume":"57","author":"Bahl","year":"2011","journal-title":"Pediatr. Blood Cancer"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1086\/605496","article-title":"Chikungunya Fever: An Epidemiological Review of a Re-Emerging Infectious Disease","volume":"49","author":"Staples","year":"2009","journal-title":"Clin. Infect. Dis."},{"key":"ref_35","unstructured":"(2022, May 16). Chikungunya Transmission Cycles in Lao PDR. Available online: https:\/\/www.pasteur.la\/project-carried-on-in-the-lab\/chikungunya-transmission-cycles-in-lao-pdr\/."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"744","DOI":"10.3855\/jidc.169","article-title":"Chikungunya: An emerging and spreading arthropod-borne viral disease","volume":"3","author":"Cavrini","year":"2009","journal-title":"J. Infect. Dev. Ctries."},{"key":"ref_37","unstructured":"(2017, June 16). Zika Virus Infection\u2014India. Available online: http:\/\/www.who.int\/csr\/don\/26-may2017-zika-ind\/en\/."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1735358","DOI":"10.1155\/2018\/1735358","article-title":"Current Status of Aedes aegypti Insecticide Resistance Development from Banjarmasin, Kalimantan, Indonesia","volume":"2018","author":"Hamid","year":"2018","journal-title":"BioMed Res. Int."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/s13071-019-3657-7","article-title":"Resistance to pyrethroid and organophosphate insecticides, and the geographical distribution and polymorphisms of target-site mutations in voltage-gated sodium channel and acetylcholinesterase 1 genes in Anopheles sinensis populations in Shanghai, China","volume":"12","author":"Fang","year":"2019","journal-title":"Parasites Vectors"},{"key":"ref_40","first-page":"19","article-title":"Effective mosquito repellent from plant-based formulation","volume":"5","author":"Shukla","year":"2018","journal-title":"Int. J. Mosq. Res."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1038\/s41598-018-36814-1","article-title":"Repellency Assessment of Nepeta cataria Essential Oils and Isolated Nepetalactones on Aedes aegypti","volume":"9","author":"Reichert","year":"2019","journal-title":"Sci. Rep."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S2222-1808(13)60069-9","article-title":"Repellent activity of herbal essential oils against Aedes aegypti (Linn.) and Culex quinquefasciatus (Say.)","volume":"3","author":"Sritabutra","year":"2013","journal-title":"Asian Pac. J. Trop. Dis."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"163","DOI":"10.22270\/jddt.v11i3.4853","article-title":"Traditional Uses, Phytochemical and Pharmacological Properties of Ficus auriculata: A Review","volume":"11","author":"Tamta","year":"2021","journal-title":"J. Drug Deliv. Ther."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1186\/1475-2875-10-S1-S11","article-title":"Plant-based insect repellents: A review of their efficacy, development and testing","volume":"10","author":"Maia","year":"2011","journal-title":"Malar. J."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"e09346","DOI":"10.1016\/j.heliyon.2022.e09346","article-title":"Combinations of plant essential oils and their major compositions inducing mortality and morphological abnormality of Aedes aegypti and Aedes albopictus","volume":"8","author":"Soonwera","year":"2022","journal-title":"Heliyon"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.sajb.2021.03.005","article-title":"Larvicidal, adulticidal and repellent activities against Aedes aegypti L. of two commonly used spices, Origanum vulgare L. and Thymus vulgaris L","volume":"140","author":"Ramos","year":"2021","journal-title":"South Afr. J. Bot."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"113678","DOI":"10.1016\/j.indcrop.2021.113678","article-title":"Larvicidal activity of Annona mucosa Jacq. extract and main constituents rolliniastatin 1 and rollinicin against Aedes aegypti and Aedes albopictus","volume":"169","author":"Rodrigues","year":"2021","journal-title":"Ind. Crop. Prod."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Manh, H.D., Hue, D.T., Hieu, N.T.T., Tuyen, D.T.T., and Tuyet, O.T. (2020). The Mosquito Larvicidal Activity of Essential Oils from Cymbopogon and Eucalyptus Species in Vietnam. Insects, 11.","DOI":"10.3390\/insects11020128"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"e04915","DOI":"10.1016\/j.heliyon.2020.e04915","article-title":"Chemical composition, insecticidal and biochemical effects of two plant oils and their major fractions against Aedes aegypti, the common vector of dengue fever","volume":"6","author":"Almadiy","year":"2020","journal-title":"Heliyon"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"e04322","DOI":"10.1016\/j.heliyon.2020.e04322","article-title":"Comparative study on larvicidal activity of green synthesized silver nanoparticles and Annona glabra (Annonaceae) aqueous extract to control Aedes aegypti and Aedes albopictus (Diptera: Culicidae)","volume":"6","author":"Amarasinghe","year":"2020","journal-title":"Heliyon"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"e20180197","DOI":"10.1590\/0037-8682-0197-2018","article-title":"Different susceptibilities of Aedes aegypti and Aedes albopictus larvae to plant-derived products","volume":"52","author":"Rodrigues","year":"2019","journal-title":"Rev. Da Soc. Bras. De Med. Trop."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"e02732","DOI":"10.1016\/j.heliyon.2019.e02732","article-title":"Antidengue potential of leaf extracts of Pavetta tomentosa and Tarenna asiatica (Rubiaceae) against dengue virus and its vector Aedes aegypti (Diptera: Culicidae)","volume":"5","author":"Pratheeba","year":"2019","journal-title":"Heliyon"},{"key":"ref_53","first-page":"1","article-title":"Larvicidal Activity of Silver Nanoparticles Synthesized Using Extracts of Ambrosia arborescens (Asteraceae) to Control Aedes aegypti L. (Diptera: Culicidae)","volume":"2018","author":"Pilaquinga","year":"2018","journal-title":"J. Nanotechnol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/S2221-1691(14)60204-5","article-title":"Larvicidal efficacies and chemical composition of essential oils of Pinus sylvestris and Syzygium aromaticum against mosquitoes","volume":"4","author":"Fayemiwo","year":"2013","journal-title":"Asian Pac. J. Trop. Biomed."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.chemosphere.2013.10.035","article-title":"Larvicidal activity of Mentha x villosa Hudson essential oil, rotundifolone and derivatives","volume":"104","author":"Lima","year":"2014","journal-title":"Chemosphere"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.fitote.2007.01.003","article-title":"Aromatic plant-derived essential oil: An alternative larvicide for mosquito control","volume":"78","author":"Pitasawat","year":"2007","journal-title":"Fitoterapia"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.actatropica.2014.07.002","article-title":"Effect of niloticin, a protolimonoid isolated from Limonia acidissima L. (Rutaceae) on the immature stages of dengue vector Aedes aegypti L. (Diptera: Culicidae)","volume":"139","author":"Reegan","year":"2014","journal-title":"Acta Trop."},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Manh, H.D., and Tuyet, O.T. (2020). Larvicidal and Repellent Activity of Mentha arvensis L. Essential Oil against Aedes aegypti. Insects, 11.","DOI":"10.3390\/insects11030198"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"17","DOI":"10.33448\/rsd-v10i17.24733","article-title":"Ateleia glazioveana and Ocimum basilicum: Plants with potential larvicidal and repellent against Aedes aegypti (Diptera, Culicidae)","volume":"10","author":"Alievi","year":"2021","journal-title":"Res. Soc. Dev."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"9176","DOI":"10.1007\/s11356-018-1515-3","article-title":"Larvicidal activity of selected plant extracts and their combination against the mosquito vectors Culex quinquefasciatus and Aedes aegypti","volume":"25","author":"Hari","year":"2018","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.sbspro.2014.10.052","article-title":"Biolarvacidal Potential of Ipomoea cairica Extracts against Key Dengue Vectors","volume":"153","author":"Ishak","year":"2014","journal-title":"Procedia-Soc. Behav. Sci."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.sajb.2020.06.020","article-title":"Mosquito larvicidal activity of Avocado (Persea americana Mill.) unripe fruit peel methanolic extract against Aedes aegypti, Culex quinquefasciatus and Anopheles stephensi","volume":"133","author":"Louis","year":"2020","journal-title":"S. Afr. J. Bot."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/S2222-1808(16)61070-8","article-title":"Ovicidal and larvicidal activities of some plant extracts against Aedes aegypti L. and Culex quinquefasciatus Say (Diptera: Culicidae)","volume":"6","author":"Munusamy","year":"2016","journal-title":"Asian Pac. J. Trop. Dis."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S2221-1691(15)30347-6","article-title":"Toxicity of Mexican native plant extracts against larvae of Aedes aegypti (Diptera: Culicidae)","volume":"5","year":"2015","journal-title":"Asian Pac. J. Trop. Biomed."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S1995-7645(10)60167-8","article-title":"Larvicidal and repellent activities of Sida acuta Burm. F. (Family: Malvaceae) against three important vector mosquitoes","volume":"3","author":"Govindarajan","year":"2010","journal-title":"Asian Pac. J. Trop. Med."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S1226-8615(08)60157-0","article-title":"Larvicidal Activity of Australian and Mexican Plant Extracts against Aedes aegypti and Culex pipiens pallens (Diptera: Culicidae)","volume":"5","author":"Kim","year":"2002","journal-title":"J. Asia-Pacific \u00c8ntomol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"S556","DOI":"10.1016\/S2222-1808(14)60676-9","article-title":"Bioefficacy of Anamirta cocculus Linn. (Menispermaceae) seed extracts against dengue vector, Aedes aegypti Linn. (Diptera: Culicidae)","volume":"4","author":"Qadir","year":"2014","journal-title":"Asian Pac. J. Trop. Dis."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"S181","DOI":"10.1016\/S2222-1808(14)60436-9","article-title":"Mosquito larvicidal efficay of Acorus calamus extracts against Aedes aegypti L. larvae","volume":"4","author":"Imam","year":"2014","journal-title":"Asian Pac. J. Trop. Dis."},{"key":"ref_69","first-page":"13","article-title":"Larvicidal and repellent effect of some Tribulus terrestris L., (Zygophyllaceae) extracts against the dengue fever mosquito, Aedes aegypti (Diptera: Culicidae)","volume":"20","author":"Alabboud","year":"2012","journal-title":"J. Saudi Chem. Soc."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"217","DOI":"10.4103\/2221-1691.231284","article-title":"Efficacies of four plant essential oils as larvicide, pupicide and oviposition deterrent agents against dengue fever mosquito, Aedes aegypti Linn. (Diptera: Culicidae)","volume":"8","author":"Chantawee","year":"2018","journal-title":"Asian Pac. J. Trop. Biomed."},{"key":"ref_71","doi-asserted-by":"crossref","unstructured":"Inocente, E.A., Nguyen, B., Manwill, P.K., Benatrehina, A., Kweka, E., Wu, S., Cheng, X., Rakotondraibe, L.H., and Piermarini, P.M. (2019). Insecticidal and Antifeedant Activities of Malagasy Medicinal Plant (Cinnamosma sp.) Extracts and Drimane-Type Sesquiterpenes against Aedes aegypti Mosquitoes. Insects, 10.","DOI":"10.3390\/insects10110373"},{"key":"ref_72","first-page":"653","article-title":"Transformation of trans-anethole using the plant pathogenic fungus Colletotrichum acutatum as biocatalyst","volume":"14","author":"Rodrigo","year":"2015","journal-title":"Rev. Mex. De Ing. Qu\u00edmica"},{"key":"ref_73","unstructured":"(2022, June 07). SpectraBase 2,6,10,15,19,23-Hexamethyltetracosane. Available online: https:\/\/spectrabase.com\/compound\/6bTmueR7Ifk."},{"key":"ref_74","unstructured":"(2022, June 09). Chemical Properties of Cis-Tagetenone. Available online: https:\/\/chemeo.com\/cid\/76-423-8\/cis-tagetenone."},{"key":"ref_75","unstructured":"(2022, June 13). PubChem Explore Chemistry, Available online: https:\/\/pubchem.ncbi.nlm.nih.gov\/compound."},{"key":"ref_76","unstructured":"(2022, June 12). (Z)-azarone, Available online: https:\/\/greenmolbd.gov.bd\/compound\/2407."},{"key":"ref_77","unstructured":"(2022, June 07). RSC Publishing Home-Chemical Journals, Books and Databases. Available online: https:\/\/pubs.rsc.org."},{"key":"ref_78","unstructured":"(2022, June 05). 1,8-cineole. Available online: https:\/\/tcichemicals.com\/IN\/en\/p\/C0542."},{"key":"ref_79","first-page":"2228","article-title":"Screening and Potential Analysis of Methanolic Leaf Extract of Mangrove Plants at East Coast Sumatera as Repellent against Aedes aegypti","volume":"10","author":"Muhaimin","year":"2018","journal-title":"J. Pharm. Sci. Res."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"117","DOI":"10.2987\/moco-32-02-117-123.1","article-title":"New Candidates for Plant-Based Repellents against Aedes aegypti","volume":"32","author":"Misni","year":"2016","journal-title":"J. Am. Mosq. Control. Assoc."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"11257","DOI":"10.1007\/s11356-016-6318-9","article-title":"Repellent and mosquitocidal effects of leaf extracts of Clausena anisata against the Aedes aegypti mosquito (Diptera: Culicidae)","volume":"23","author":"Mukandiwa","year":"2016","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_82","first-page":"669","article-title":"Efficacy of essential oils from Citrus plants against mosquito vectors Aedes\u00a0aegypti (Linn.) and Culex quinquefasciatus (Say)","volume":"11","author":"Soonwera","year":"2015","journal-title":"Int. J. Agric. Technol."},{"key":"ref_83","first-page":"231","article-title":"Prevention of Dengue fever through plant based mosquito repellent Clausena dentata (Willd.) M. Roem (Family: Rutaceae) essential oil against Aedes aegypti l. (Diptera: Culicidae) mosquito","volume":"14","author":"Rajkumar","year":"2010","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1080\/0972060X.2019.1661796","article-title":"Selected Essential Oils as Repellents against Aedes aegypti: Validation of the Bioconstituents Using Gas Chromatography","volume":"22","author":"Lim","year":"2019","journal-title":"J. Essent. Oil Bear. Plants"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"111609","DOI":"10.1016\/j.indcrop.2019.111609","article-title":"Chemical composition and repellent activity of native plants essential oils against dengue mosquito, Aedes aegypti","volume":"140","author":"Azeem","year":"2019","journal-title":"Ind. Crop. Prod."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1007\/s00436-015-4409-z","article-title":"Angelica sinensis (Umbelliferae) with proven repellent properties against Aedes aegypti, the primary dengue fever vector in Thailand","volume":"114","author":"Champakaew","year":"2015","journal-title":"Parasitol. Res."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"S449","DOI":"10.1016\/S2222-1808(14)60489-8","article-title":"Adulticidal properties of Pithecellobium dulce (Roxb.) Benth. (Family: Fabaceae) against dengue vector, Aedes aegypti (Linn.) (Diptera: Culicidae)","volume":"4","author":"Rajeswary","year":"2014","journal-title":"Asian Pac. J. Trop. Dis."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"25","DOI":"10.2987\/16-6585.1","article-title":"Insecticidal and Repellent Activity of Several Plant-Derived Essential Oils against Aedes aegypti","volume":"33","author":"Castillo","year":"2017","journal-title":"J. Am. Mosq. Control. Assoc."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s41936-021-00233-y","article-title":"Screening of some weed extracts for ovicidal and larvicidal activities against dengue vector Aedes aegypti","volume":"82","author":"Torawane","year":"2021","journal-title":"J. Basic Appl. Zool."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"8352","DOI":"10.1021\/acs.jafc.6b01668","article-title":"Isolation and Identification of Mosquito (Aedes aegypti) Biting-Deterrent Compounds from the Native American Ethnobotanical Remedy Plant Hierochlo\u00eb odorata (Sweetgrass)","volume":"64","author":"Cantrell","year":"2016","journal-title":"J. Agric. Food Chem."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1016\/j.biortech.2008.10.055","article-title":"Chemical composition, oviposition deterrent and larvicidal activities against Aedes aegypti of essential oils from Piper marginatum Jacq. (Piperaceae)","volume":"100","author":"Autran","year":"2009","journal-title":"Bioresour. Technol."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.3389\/fphys.2019.01591","article-title":"A Review of Resistance Mechanisms of Synthetic Insecticides and Botanicals, Phytochemicals, and Essential Oils as Alternative Larvicidal Agents against Mosquitoes","volume":"10","year":"2020","journal-title":"Front. Physiol."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"2169959","DOI":"10.1080\/26895293.2023.2169959","article-title":"Chemical screening and mosquitocidal activity of essential oil derived from Mikania scandens (L.) Willd. against Anopheles gambiae Giles and their non-toxicity on mosquito predators","volume":"16","author":"Radhakrishnan","year":"2023","journal-title":"All Life."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"159512","DOI":"10.1016\/j.scitotenv.2022.159512","article-title":"Eco-friendly biosynthesis of TiO2 nanoparticles using Desmostachya bipinnata extract: Larvicidal and pupicidal potential against Aedes aegypti and Spodoptera litura and acute toxicity in non-target organisms","volume":"858","author":"Karthi","year":"2023","journal-title":"Sci. Total. Environ."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1080\/15569543.2020.1851723","article-title":"Volatile toxin of Limonia acidissima (L.) produced larvicidal, developmental, repellent, and adulticidal toxicity effects on Aedes aegypti (L.)","volume":"41","author":"Chellappandian","year":"2022","journal-title":"Tox. Rev."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"15654","DOI":"10.1007\/s11356-021-16219-w","article-title":"Larvicidal and repellent activity of N-methyl-1-adamantylamine and oleic acid a major derivative of bael tree ethanol leaf extracts against dengue mosquito vector and their biosafety on natural predator","volume":"29","author":"Chellappandian","year":"2021","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"101915","DOI":"10.1016\/j.bcab.2021.101915","article-title":"The efficacy of methanolic extract of Swietenia mahagoni Jacq. (Meliaceae) and a commercial insecticide against laboratory and field strains of Aedes aegypti (Linn.) and their impact on its predator Toxorhnchites splendens","volume":"31","author":"Karthi","year":"2021","journal-title":"Biocatal. Agric. Biotechnol."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/28\/5\/2386\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:48:21Z","timestamp":1760122101000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/28\/5\/2386"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,5]]},"references-count":97,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,3]]}},"alternative-id":["molecules28052386"],"URL":"https:\/\/doi.org\/10.3390\/molecules28052386","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,5]]}}}