{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T14:16:01Z","timestamp":1781187361871,"version":"3.54.1"},"reference-count":42,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,3,19]],"date-time":"2023-03-19T00:00:00Z","timestamp":1679184000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Natural Science Fund of Education Department of Anhui Province","award":["KJ2020A0791"],"award-info":[{"award-number":["KJ2020A0791"]}]},{"name":"Natural Science Fund of Education Department of Anhui Province","award":["zdxk202104"],"award-info":[{"award-number":["zdxk202104"]}]},{"name":"Key Subject of Anhui Xinhua University","award":["KJ2020A0791"],"award-info":[{"award-number":["KJ2020A0791"]}]},{"name":"Key Subject of Anhui Xinhua University","award":["zdxk202104"],"award-info":[{"award-number":["zdxk202104"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>The composition of volatile oils of the leaf and stem of Farfugium japonicum (L.) Kitamura were prepared by supercritical fluid extraction (SFE)-CO2. A total 47 and 40 compounds were identified by GC\/MS analysis, respectively, and only 13 compounds coexisted. The main constituent types in the leaf oil included alcohols (34.1%), hydrocarbons (24.1%), terpenoids (16.2%), benzenes (7.5%), and fatty acids (4.9%). In the stem oil, the constituent types chiefly included benzenes (18.8%), ketones (13.9%), terpenoids (17.0%), fatty acids (8.8%), phenolics (8.7%), steroids (8.6%), hydrocarbons (8.0%), and esters (5.7%). The predominant volatile compounds in the stem were 2-(1-cyclopent-1-enyl-1-methylethyl) cyclopentanone (11.7%), 1,2,3,4,5,6,7,8-octahydro- 9,10-dimethyl-anthracene (8.4%), 5-heptylresorcinol (6.5%), and \u03b1-sitosterol (5.2%). Those in the leaf mainly included (E)-3-hexen-1-ol (13.7%) and (Z)-3-hexen-1-ol (14.0%). This demonstrated a significant difference in the composition of both oils. Further study showed that stem oils demonstrated the highest DPPH (1,1-diphenyl-2-pinylhydrazyl) and \u00b7OH free radical scavenging capacities at IC50 values of 9.22 and 0.90 mg\/mL, respectively. In addition, they demonstrated the strongest antibacterial capacity against the Gram-positive bacteria methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) at a minimum inhibitory concentration (MIC) of 0.16 mg\/mL. This could be due to the SFE-CO2 extraction and the high accumulation of benzenes, terpenoids, and phenolics in the stem. In particular, the monoterpenes presented in terpenoids could play a special role in these findings.<\/jats:p>","DOI":"10.3390\/molecules28062774","type":"journal-article","created":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T03:30:31Z","timestamp":1679283031000},"page":"2774","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Composition and Antioxidative and Antibacterial Activities of the Essential Oil from Farfugium japonicum"],"prefix":"10.3390","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8348-1860","authenticated-orcid":false,"given":"Qiang","family":"Wei","sequence":"first","affiliation":[{"name":"School of Medicine, Anhui Xinhua University, Hefei 230088, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Han","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Medicine, Anhui Xinhua University, Hefei 230088, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"623","DOI":"10.5650\/jos.57.623","article-title":"Chemical composition and anti-inflammatory effects of essential oil from Farfugium japonicum flower","volume":"57","author":"Kim","year":"2008","journal-title":"J. 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