{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:36:51Z","timestamp":1790800611756,"version":"4.1.0"},"reference-count":54,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,4,7]],"date-time":"2023-04-07T00:00:00Z","timestamp":1680825600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Key R&amp;D Program of China","award":["2020YFA0710700"],"award-info":[{"award-number":["2020YFA0710700"]}]},{"name":"National Key R&amp;D Program of China","award":["51873201"],"award-info":[{"award-number":["51873201"]}]},{"name":"National Key R&amp;D Program of China","award":["YD2060002015"],"award-info":[{"award-number":["YD2060002015"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2020YFA0710700"],"award-info":[{"award-number":["2020YFA0710700"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51873201"],"award-info":[{"award-number":["51873201"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["YD2060002015"],"award-info":[{"award-number":["YD2060002015"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fundamental Research Funds for the Central Universities","award":["2020YFA0710700"],"award-info":[{"award-number":["2020YFA0710700"]}]},{"name":"Fundamental Research Funds for the Central Universities","award":["51873201"],"award-info":[{"award-number":["51873201"]}]},{"name":"Fundamental Research Funds for the Central Universities","award":["YD2060002015"],"award-info":[{"award-number":["YD2060002015"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>The conversion of lignocellulose into valuable chemicals has been recognized as the key technology in green chemistry. However, selective degradation of hemicellulose and cellulose with the production of lignin is still a challenge. Therefore, a two-step process has been developed to degrade corncob into xylose and glucose under mild conditions. At first, the corncob was treated with the lower concentration of zinc chloride aqueous solution (30\u201355 w%) at 95 \u00b0C with a short reaction time (8\u201312 min) and 30.4 w% (selectivity = 89%) of xylose obtained with a solid residue of the composite of cellulose and lignin. Next, the solid residue was treated with a high concentration of zinc chloride aqueous solution (65\u201385 w%) at 95 \u00b0C for about 10 min, and 29.4 w% (selectivity = 92%) of glucose can be obtained. Combining the two steps, the total yield of xylose is 97%, while glucose is 95%. In addition, high pure lignin can be obtained simultaneously, which was confirmed using HSQC studies. Furthermore, for the solid residue of the first-step reaction, a ternary deep eutectic solvent (DES) (choline chloride\/oxalic acid\/1,4-butanediol, ChCl\/OA\/BD) has been used to separate the cellulose and lignin efficiently, and high-quality cellulose (Re-C) and lignin (Re-L) were obtained. Furthermore, it provides a simple method to disassemble the lignocellulose for monosaccharides, lignin, and cellulose.<\/jats:p>","DOI":"10.3390\/molecules28083306","type":"journal-article","created":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T03:24:18Z","timestamp":1681097058000},"page":"3306","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Fast and Selective Degradation of Biomass for Xylose, Glucose and Lignin under Mild Conditions"],"prefix":"10.3390","volume":"28","author":[{"given":"Shangzhong","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Chemical Physics, University of Science and Technology of China, Jinzai Road 96, Hefei 230026, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Duan","sequence":"additional","affiliation":[{"name":"Department of Chemical Physics, University of Science and Technology of China, Jinzai Road 96, Hefei 230026, China"},{"name":"Key Laboratory of Anhui for Tobacco Chemistry, Hefei 230088, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changchang","family":"Teng","sequence":"additional","affiliation":[{"name":"Department of Chemical Physics, University of Science and Technology of China, Jinzai Road 96, Hefei 230026, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongdong","family":"Quan","sequence":"additional","affiliation":[{"name":"Department of Chemical Physics, University of Science and Technology of China, Jinzai Road 96, Hefei 230026, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuguo","family":"Yang","sequence":"additional","affiliation":[{"name":"Inner Mongolia Key Laboratory of Polyol Chemical New Material Enterprise, Chifeng Ruiyang Chemical Co., Ltd., Pingzhuang, Chifeng 024076, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyan","family":"Li","sequence":"additional","affiliation":[{"name":"Inner Mongolia Key Laboratory of Polyol Chemical New Material Enterprise, Chifeng Ruiyang Chemical Co., Ltd., Pingzhuang, Chifeng 024076, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohe","family":"Li","sequence":"additional","affiliation":[{"name":"Inner Mongolia Key Laboratory of Polyol Chemical New Material Enterprise, Chifeng Ruiyang Chemical Co., Ltd., Pingzhuang, Chifeng 024076, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6063-270X","authenticated-orcid":false,"given":"Lifeng","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Chemical Physics, University of Science and Technology of China, Jinzai Road 96, Hefei 230026, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"5588","DOI":"10.1039\/c1cs15124j","article-title":"Catalytic conversion of lignocellulosic biomass to fine chemicals and fuels","volume":"40","author":"Zhou","year":"2011","journal-title":"Chem. Soc. Rev."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"126033","DOI":"10.1016\/j.biortech.2021.126033","article-title":"Hydrothermal pretreatment of lignocellulosic biomass for hemicellulose recovery","volume":"342","author":"Scapini","year":"2021","journal-title":"Bioresour. Technol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.biortech.2017.08.059","article-title":"Integrated microwave and alkaline treatment for the separation between hemicelluloses and cellulose from cellulosic fibers","volume":"247","author":"Liu","year":"2018","journal-title":"Bioresour. Technol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"4098","DOI":"10.1021\/acssuschemeng.7b04463","article-title":"Sodium Chloride-Assisted Depolymerization of Xylo-oligomers to Xylose","volume":"6","author":"Jiang","year":"2018","journal-title":"ACS Sustain. Chem. Eng."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1039\/C7EE03208K","article-title":"A mechanistic model of fast pyrolysis of hemicellulose","volume":"11","author":"Zhou","year":"2018","journal-title":"Energy Environ. Sci."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"3902","DOI":"10.1039\/C9GC00252A","article-title":"Cellulolytic enzyme-aided extraction of hemicellulose from switchgrass and its characteristics","volume":"21","author":"Ding","year":"2019","journal-title":"Green Chem."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.biortech.2015.11.036","article-title":"Biochemical conversion of sugarcane straw hemicellulosic hydrolyzate supplemented with co-substrates for xylitol production","volume":"200","author":"Costa","year":"2016","journal-title":"Bioresour. Technol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/jctb.4168","article-title":"Integrated furfural production as a renewable fuel and chemical platform from lignocellulosic biomass","volume":"89","author":"Cai","year":"2014","journal-title":"J. Chem. Technol. Biotechnol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"117274","DOI":"10.1016\/j.carbpol.2020.117274","article-title":"Hydrothermal treatment on depolymerization of hemicellulose of mango seed shell for the production of xylooligosaccharides","volume":"253","author":"Monteiro","year":"2021","journal-title":"Carbohydr. Polym."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"3942","DOI":"10.1039\/C4GC00398E","article-title":"Hemicellulose-derived chemicals: One-step production of furfuryl alcohol from xylose","volume":"16","author":"Perez","year":"2014","journal-title":"Green Chem."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"5949","DOI":"10.1039\/C7GC02671D","article-title":"Superbase ionic liquids for effective cellulose processing from dissolution to carbonization","volume":"19","author":"Kuzmina","year":"2017","journal-title":"Green Chem."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"8915","DOI":"10.1016\/j.biortech.2010.06.125","article-title":"A biorefinery processing perspective: Treatment of lignocellulosic materials for the production of value-added products","volume":"101","author":"FitzPatrick","year":"2010","journal-title":"Bioresour. Technol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.biortech.2016.12.049","article-title":"Assessment of solvents for cellulose dissolution","volume":"228","author":"Ghasemi","year":"2017","journal-title":"Bioresour. Technol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.renene.2017.01.023","article-title":"Saccharification of cellulose in the ionic liquids and glucose recovery","volume":"106","author":"Liu","year":"2017","journal-title":"Renew. Energy"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"9201","DOI":"10.1007\/s10570-020-03411-3","article-title":"Homogenous hydrolysis of cellulose to glucose in an inorganic ionic liquid catalyzed by zeolites","volume":"27","author":"Wu","year":"2020","journal-title":"Cellulose"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3183\/npprj-2015-30-01-p043-057","article-title":"Ioncell-F: A high-strength regenerated cellulose fibre","volume":"30","author":"Sixta","year":"2015","journal-title":"Nordic Pulp Paper Res. J."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1039\/C7GC03318D","article-title":"Direct catalytic conversion of glucose and cellulose","volume":"20","author":"Li","year":"2018","journal-title":"Green Chem."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.biortech.2019.01.120","article-title":"Ruthenium trichloride catalyzed conversion of cellulose into 5-hydroxymethylfurfural in biphasic system","volume":"279","author":"Yan","year":"2019","journal-title":"Bioresour. Technol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/j.jclepro.2018.12.276","article-title":"Clean production of 5-hydroxymethylfurfural from cellulose using a hydrothermal\/biomass-based carbon catalyst","volume":"213","author":"Wu","year":"2019","journal-title":"J. Clean. Prod."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1039\/C4GC02034K","article-title":"Recent advances in the catalytic production of glucose from lignocellulosic biomass","volume":"17","author":"Wang","year":"2015","journal-title":"Green Chem."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"8086","DOI":"10.1021\/acssuschemeng.0c01348","article-title":"Perspective on Technical Lignin Fractionation","volume":"8","author":"Sadeghifar","year":"2020","journal-title":"ACS Sustain. Chem. Eng."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"122784","DOI":"10.1016\/j.biortech.2020.122784","article-title":"The critical role of lignin in lignocellulosic biomass conversion and recent pretreatment strategies: A comprehensive review","volume":"301","author":"Yoo","year":"2020","journal-title":"Bioresour. Technol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1039\/C8GC00900G","article-title":"Multiple hydrogen bond coordination in three-constituent deep eutectic solvents enhances lignin fractionation from biomass","volume":"20","author":"Xia","year":"2018","journal-title":"Green Chem."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.indcrop.2018.07.010","article-title":"Improving enzymatic saccharification of eucalyptus with a pretreatment process using MgCl2","volume":"123","author":"Yang","year":"2018","journal-title":"Ind. Crops Prod."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1021\/ie3019609","article-title":"Effects and Mechanism of Metal Chloride Salts on Pretreatment and Enzymatic Digestibility of Corn Stover","volume":"52","author":"Kamireddy","year":"2013","journal-title":"Ind. Eng. Chem. Res."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"2795","DOI":"10.1007\/s10570-021-04344-1","article-title":"All-cellulose material prepared using aqueous zinc chloride solution","volume":"29","author":"Nemoto","year":"2021","journal-title":"Cellulose"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.carbpol.2015.09.007","article-title":"Zinc chloride aqueous solution as a solvent for starch","volume":"136","author":"Lin","year":"2016","journal-title":"Carbohydr. Polym."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1021\/ic5024532","article-title":"Crystalline and liquid structure of zinc chloride trihydrate: A unique ionic liquid","volume":"54","author":"Wilcox","year":"2015","journal-title":"Inorg. Chem."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"122244","DOI":"10.1016\/j.biortech.2019.122244","article-title":"Comparative study on different pretreatment on enzymatic hydrolysis of corncob residues","volume":"295","author":"Liu","year":"2020","journal-title":"Bioresour. Technol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.biortech.2018.02.004","article-title":"An integrated process for xylooligosaccharide and bioethanol production from corncob","volume":"256","author":"Boonchuay","year":"2018","journal-title":"Bioresour. Technol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"127977","DOI":"10.1016\/j.biortech.2022.127977","article-title":"Production of xylo-oligosaccharides and ethanol from corncob by combined tartaric acid hydrolysis with simultaneous saccharification and fermentation","volume":"363","author":"Wen","year":"2022","journal-title":"Bioresour. Technol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"7429","DOI":"10.1039\/D2GC01692C","article-title":"A hemicellulose and lignin-first process for corn stover valorization catalyzed by aluminum sulfate in \u03b3-butyrolactone\/water co-solvent","volume":"24","author":"Luo","year":"2022","journal-title":"Green Chem."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s12010-007-8066-2","article-title":"An alternative application to the Portuguese agro-industrial residue: Wheat straw","volume":"147","author":"Ruzene","year":"2008","journal-title":"Appl. Biochem. Biotechnol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"125979","DOI":"10.1016\/j.biortech.2021.125979","article-title":"Two-step acetic acid\/sodium acetate and xylanase hydrolysis for xylooligosaccharides production from corncob","volume":"342","author":"Liao","year":"2021","journal-title":"Bioresour. Technol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"125680","DOI":"10.1016\/j.biortech.2021.125680","article-title":"Efficient production of xylooligosaccharides and fermentable sugars from corncob by propionic acid and enzymatic hydrolysis","volume":"342","author":"Liao","year":"2021","journal-title":"Bioresour. Technol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"119217","DOI":"10.1016\/j.carbpol.2022.119217","article-title":"Effect of pretreatments on production of xylooligosaccharides and monosaccharides from corncob by a two-step hydrolysis","volume":"285","author":"Hao","year":"2022","journal-title":"Carbohydr. Polym."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"127800","DOI":"10.1016\/j.biortech.2022.127800","article-title":"Integrated xylooligosaccharides production from imidazole-treated sugarcane bagasse with application of in house produced enzymes","volume":"362","author":"Soccol","year":"2022","journal-title":"Bioresour. Technol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"102874","DOI":"10.1016\/j.eti.2022.102874","article-title":"Multienzymatic conversion of monosaccharides from birch biomass after pretreatment","volume":"28","author":"Bachosz","year":"2022","journal-title":"Environ. Technol. Innov."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"126298","DOI":"10.1016\/j.biortech.2021.126298","article-title":"Green approach to produce xylo-oligosaccharides and glucose by mechanical-hydrothermal pretreatment","volume":"344","author":"Zhang","year":"2022","journal-title":"Bioresour. Technol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"126795","DOI":"10.1016\/j.biortech.2022.126795","article-title":"Co-production of xylooligosaccharides and glucose from birch sawdust by hot water pretreatment and enzymatic hydrolysis","volume":"348","author":"Fang","year":"2022","journal-title":"Bioresour. Technol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"125425","DOI":"10.1016\/j.jhazmat.2021.125425","article-title":"Selective degradation and oxidation of hemicellulose in corncob to oligosaccharides: From biomass into masking agent for sustainable leather tanning","volume":"413","author":"Jiang","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"128937","DOI":"10.1016\/j.biortech.2023.128937","article-title":"Selective Degradation of Hemicellulose and Lignin for Improving Enzymolysis Efficiency via Pretreatment Using Deep Eutectic Solvents","volume":"376","author":"Sun","year":"2023","journal-title":"Bioresour. Technol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s13399-018-0357-z","article-title":"Selective hemicellulose hydrolysis of Scots pine sawdust","volume":"9","author":"Rusanen","year":"2018","journal-title":"Biomass Convers. Biorefinery"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1002\/(SICI)1097-4628(19990228)71:9<1441::AID-APP8>3.0.CO;2-G","article-title":"Ultraviolet spectra and structure of zinc-cellulose complexes in zinc chloride solution","volume":"71","author":"Xu","year":"1999","journal-title":"J. Appl. Polym. Sci."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"24930","DOI":"10.1021\/acsami.8b07309","article-title":"Facilitated Transport of CO(2) through the Transparent and Flexible Cellulose Membrane Promoted by Fixed-Site Carrier","volume":"10","author":"Zhang","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.gee.2019.01.009","article-title":"One-pot Degradation of Cellulose into Carbon Dots and Organic Acids in its Homogeneous Aqueous Solution","volume":"4","author":"Su","year":"2019","journal-title":"Green Energy Environ."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1901316","DOI":"10.1002\/advs.201901316","article-title":"Evolution and Synthesis of Carbon Dots: From Carbon Dots to Carbonized Polymer Dots","volume":"6","author":"Xia","year":"2019","journal-title":"Adv. Sci."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"4181","DOI":"10.1021\/acs.biomac.1c00706","article-title":"Synthesis of Highly Ion-Conductive Lignin Eutectogels in a Ternary Deep Eutectic Solvent and Nitrogen-Doped 3D Hierarchical Porous Carbons for Supercapacitors","volume":"22","author":"Ma","year":"2021","journal-title":"Biomacromolecules"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"2984","DOI":"10.1021\/acsomega.8b00057","article-title":"Fast Disassembly of Lignocellulosic Biomass to Lignin and Sugars by Molten Salt Hydrate at Low Temperature for Overall Biorefinery","volume":"3","author":"Bi","year":"2018","journal-title":"ACS Omega"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"112140","DOI":"10.1016\/j.molliq.2019.112140","article-title":"Dissolution behavior of microcrystalline cellulose in DBU-based deep eutectic solvents: Insights from spectroscopic investigation and quantum chemical calculations","volume":"299","author":"Fu","year":"2020","journal-title":"J. Mol. Liq."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.molliq.2016.05.008","article-title":"Cellulose dissolution and regeneration using various imidazolium based protic ionic liquids","volume":"238","author":"Meenatchi","year":"2017","journal-title":"J. Mol. Liq."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"3909","DOI":"10.1021\/acssuschemeng.1c08095","article-title":"Dyeing-Inspired Sustainable and Low-Cost Modified Cellulose-Based TENG for Energy Harvesting and Sensing","volume":"10","author":"Yao","year":"2022","journal-title":"ACS Sustain. Chem. Eng."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/S1003-6326(13)62536-4","article-title":"Predominance diagrams for Zn(II)\u2013NH3\u2013Cl\u2013\u2013H2O system","volume":"23","author":"Ding","year":"2013","journal-title":"Trans. Nonferrous Met. Soc. China"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"3257","DOI":"10.1039\/D2GC00264G","article-title":"Tailored one-pot lignocellulose fractionation to maximize biorefinery toward versatile xylochemicals and nanomaterials","volume":"24","author":"Yu","year":"2022","journal-title":"Green Chem."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/28\/8\/3306\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:12:19Z","timestamp":1760123539000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/28\/8\/3306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,7]]},"references-count":54,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,4]]}},"alternative-id":["molecules28083306"],"URL":"https:\/\/doi.org\/10.3390\/molecules28083306","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,7]]}}}