{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:55:44Z","timestamp":1787313344109,"version":"build-2736575974"},"reference-count":37,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T00:00:00Z","timestamp":1681257600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Hebei Provincial High level Talents Funding Project","award":["A202001004"],"award-info":[{"award-number":["A202001004"]}]},{"name":"Hebei Provincial High level Talents Funding Project","award":["YJ201911"],"award-info":[{"award-number":["YJ201911"]}]},{"name":"Scientific Research Foundation for the Introduced Talent of Hebei Agricultural University","award":["A202001004"],"award-info":[{"award-number":["A202001004"]}]},{"name":"Scientific Research Foundation for the Introduced Talent of Hebei Agricultural University","award":["YJ201911"],"award-info":[{"award-number":["YJ201911"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>A novel, molecularly imprinted, upconversion fluorescence probe (UCNP@MIFP) for sulfonamide sensing was fabricated by Pickering emulsion polymerization using UCNP@SiO2 particles as the stabilizer and sulfamethazine\/sulfamerazine as the co-templates. The synthesis conditions of the UCNP@MIFP were optimized, and the synthesized probe was characterized by scanning electron microscopy, Fourier transform infrared spectrometer, thermogravimetric analyzer, and fluorescence spectrometer. The UCNP@MIFPs showed a good adsorption capacity and a fast kinetic feature for the template. The selectivity experiment revealed that the UCNP@MIFP has a broad-spectrum molecular recognition capability. Good linear relationships were obtained over the concentration range of 1\u201310 ng\/mL for sulfamerazine, sulfamethazine, sulfathiazole, and sulfafurazole, with low limits of detection in the range of 1.37\u20132.35 ng\/mL. The prepared UCNP@MIFP has the potential to detect four sulfonamide residues in food and environmental water.<\/jats:p>","DOI":"10.3390\/molecules28083391","type":"journal-article","created":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T02:57:08Z","timestamp":1681268228000},"page":"3391","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A Novel Sulfonamide, Molecularly Imprinted, Upconversion Fluorescence Probe Prepared by Pickering Emulsion Polymerization and Its Adsorption and Optical Sensing Performance"],"prefix":"10.3390","volume":"28","author":[{"given":"Qidi","family":"Pan","sequence":"first","affiliation":[{"name":"College of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Gao","sequence":"additional","affiliation":[{"name":"College of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Meng","sequence":"additional","affiliation":[{"name":"College of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianghua","family":"Guo","sequence":"additional","affiliation":[{"name":"Qian\u2019an Agricultural and Rural Bureau, Qian\u2019an 064400, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meitian","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiwei","family":"Tang","sequence":"additional","affiliation":[{"name":"College of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"100589","DOI":"10.1016\/j.jics.2022.100589","article-title":"Determination of sulfonamide residues in cultured sea cucumber by pre-column derivatization capillary electrophoresis with fluorescence detection","volume":"99","author":"Bai","year":"2022","journal-title":"J. Indian Chem. Soc."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"135045","DOI":"10.1016\/j.foodchem.2022.135045","article-title":"Fluorimetric identification of sulfonamides by carbon dots embedded photonic crystal molecularly imprinted sensor array","volume":"407","author":"Zhang","year":"2023","journal-title":"Food Chem."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.tifs.2016.03.015","article-title":"Analytical strategies for the detection and quantification of antibiotic residues in aquaculture fishes: A review","volume":"52","author":"Santos","year":"2016","journal-title":"Trends Food Sci. Tech."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.envint.2019.03.046","article-title":"A novel sulfonamide resistance mechanism by two-component flavin-dependent monooxygenase system in sulfonamide-degrading actinobacteria","volume":"127","author":"Kim","year":"2019","journal-title":"Environ. Int."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.foodcont.2015.12.012","article-title":"Establishment of a method to detect sulfonamide residues in chicken meat and eggs by high-performance liquid chromatography","volume":"72","author":"Premarathne","year":"2017","journal-title":"Food Control"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.fshw.2020.05.002","article-title":"Rapid analysis of fifteen sulfonamide residues in pork and fish samples by automated on-line solid phase extraction coupled to liquid chromatography\u2013tandem mass spectrometry","volume":"9","author":"Ma","year":"2020","journal-title":"Food Sci. Hum. Wellness"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"7526","DOI":"10.1021\/jf1011616","article-title":"Validation of an enzyme-linked immunosorbent assay for detecting sulfonamides in feed resources","volume":"58","author":"Jimenez","year":"2010","journal-title":"J. Agric. Food Chem."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"8603","DOI":"10.1021\/acs.analchem.1c01530","article-title":"Improving SERS sensitivity toward trace sulfonamides: The key role of trade-off interfacial interactions among the target molecules, anions, and cations on the SERS active surface","volume":"93","author":"Zhou","year":"2021","journal-title":"Anal. Chem."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.bios.2017.03.027","article-title":"Dual lanthanide-doped complexes: The development of a time-resolved ratiometric fluorescent probe for anthrax biomarker and a paper-based visual sensor","volume":"94","author":"Wang","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1038\/s41467-018-04813-5","article-title":"Advances in highly doped upconversion nanoparticles","volume":"9","author":"Wen","year":"2018","journal-title":"Nat. Commun."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"114581","DOI":"10.1016\/j.bios.2022.114581","article-title":"An upconversion biosensor based on DNA hybridization and DNA-templated silver nanoclusters for the determination of acrylamide","volume":"215","author":"Rong","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"111541","DOI":"10.1016\/j.lwt.2021.111541","article-title":"A fluorescence resonance energy transfer probe based on functionalized graphene oxide and upconversion nanoparticles for sensitive and rapid detection of zearalenone","volume":"147","author":"Li","year":"2021","journal-title":"LWT-Food Sci. Tech."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"128434","DOI":"10.1016\/j.snb.2020.128434","article-title":"A highly sensitive upconversion nanoparticles-WS2 nanosheet sensing platform for Escherichia coli detection","volume":"320","author":"Wang","year":"2020","journal-title":"Sens. Actuat. B Chem."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.foodcont.2014.10.003","article-title":"Aptamer-based fluorescence biosensor for chloramphenicol determination using upconversion nanoparticles","volume":"50","author":"Wu","year":"2015","journal-title":"Food Control"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"118654","DOI":"10.1016\/j.saa.2020.118654","article-title":"Ultra-sensitive detection of malathion residues using FRET-based upconversion fluorescence sensor in food","volume":"241","author":"Chen","year":"2020","journal-title":"Spectrochim. Acta"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"128838","DOI":"10.1016\/j.snb.2020.128838","article-title":"A core-shell molecularly imprinted optical sensor based on the upconversion nanoparticles decorated with Zinc-based metal-organic framework for selective and rapid detection of octopamine","volume":"326","author":"Cao","year":"2021","journal-title":"Sens. Actuat. B Chem."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"109074","DOI":"10.1016\/j.foodcont.2022.109074","article-title":"Recent advances in the application of molecularly imprinted polymers (MIPs) in food analysis","volume":"139","author":"Basak","year":"2022","journal-title":"Food Control"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"127063","DOI":"10.1016\/j.foodchem.2020.127063","article-title":"Novel magnetic fluorescent probe based on carbon quantum dots-doped molecularly imprinted polymer for AHLs signaling molecules sensing in fish juice and milk","volume":"328","author":"Cui","year":"2020","journal-title":"Food Chem."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.talanta.2018.01.006","article-title":"Upconversion particle@Fe3O4@molecularly imprinted polymer with controllable shell thickness as high-performance fluorescent probe for sensing quinolones","volume":"181","author":"Tang","year":"2018","journal-title":"Talanta"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"129301","DOI":"10.1016\/j.colsurfa.2022.129301","article-title":"Surface imprinted upconversion nanoparticles for selective albumin recognition","volume":"649","author":"Goodarzi","year":"2022","journal-title":"Colloids Surf. A"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"125978","DOI":"10.1016\/j.colsurfa.2020.125978","article-title":"Hollow molecularly imprinted microspheres made by w\/o\/w double Pickering emulsion polymerization stabilized by graphene oxide quantum dots targeted for determination of l-cysteine concentration","volume":"612","author":"Hosseinzadeh","year":"2021","journal-title":"Colloids Surf. A"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.talanta.2018.08.030","article-title":"Detection of hemoglobin using hybrid molecularly imprinted polymers\/carbon quantum dots-based nanobiosensor prepared from surfactant-free Pickering emulsion","volume":"190","author":"Zhou","year":"2018","journal-title":"Talanta"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Zhao, X., Cui, Y., Wang, J., and Wang, J. (2019). Preparation of fluorescent molecularly imprinted polymers via Pickering emulsion interfaces and the application for visual sensing analysis of Listeria Monocytogenes. Polymers, 11.","DOI":"10.3390\/polym11060984"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Xiong, Y., Wang, Q., Duan, M., Xu, J., Chen, J., and Fang, S. (2018). Preparation of molecularly imprinted microspheres as biomimetic recognition material for in-Situ adsorption and selective chemiluminescence determination of bisphenol A. Polymers, 10.","DOI":"10.3390\/polym10070780"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"e21205","DOI":"10.1016\/S1872-2040(21)60118-4","article-title":"Progress in application of dual\/multi-template molecularly imprinted polymers","volume":"49","author":"Shen","year":"2021","journal-title":"Chin. J. Anal. Chem."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"136045","DOI":"10.1016\/j.foodchem.2023.136045","article-title":"A biobased magnetic dual-dummy-template molecularly imprinted polymer using a deep eutectic solvent as a coporogen for highly selective enrichment of organophosphates","volume":"418","author":"Surapong","year":"2023","journal-title":"Food Chem."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"116939","DOI":"10.1016\/j.jelechem.2022.116939","article-title":"Highly selective and specific monitoring of pollutants using dual template imprinted MIP sensor","volume":"926","author":"Singh","year":"2022","journal-title":"Electroanal. Chem."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"130104","DOI":"10.1016\/j.colsurfa.2022.130104","article-title":"Synthesis of polystyrene\/silica and poly(styrene-co-butyl acrylate)\/silica nanocomposite particles by Pickering emulsion polymerization with non-functionalized silica nanoparticles","volume":"654","author":"Ip","year":"2022","journal-title":"Colloids Surf. A"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"121457","DOI":"10.1016\/j.saa.2022.121457","article-title":"Selective detection of carbendazim using a upconversion fluorescence sensor modified by biomimetic molecularly imprinted polymers","volume":"284","author":"Wang","year":"2023","journal-title":"Spectrochim. Acta A"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"111446","DOI":"10.1016\/j.colsurfb.2020.111446","article-title":"Lotus seedpod-like molecularly imprinted polymers fabricated by MOF-808 stabilized Pickering emulsion and their specific recognition of hemoglobin","volume":"197","author":"Sun","year":"2021","journal-title":"Colloids Surf. B"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"134627","DOI":"10.1016\/j.foodchem.2022.134627","article-title":"Molecularly imprinted polymer film loaded on the metal\u2013organic framework with improved performance using stabilized gold-doped graphite carbon nitride nanosheets for the single-step detection of Fenamiphos","volume":"404","author":"Mehmandoust","year":"2023","journal-title":"Food Chem."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"8940","DOI":"10.1021\/jp0734530","article-title":"Site-selective photoinduced electron transfer from alcoholic solvents to the chromophore facilitated by hydrogen bonding: A new fluorescence quenching mechanism","volume":"111","author":"Zhao","year":"2007","journal-title":"J. Phys. Chem. B"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1021\/ac802375a","article-title":"Surface molecular imprinting on Mn-doped ZnS quantum dots for room-temperature phosphorescence optosensing of pentachlorophenol in water","volume":"81","author":"Wang","year":"2009","journal-title":"Anal. Chem."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.bios.2015.10.084","article-title":"Enzymatic-induced upconversion photoinduced electron transfer for sensing tyrosine in human serum","volume":"77","author":"Wu","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"107898","DOI":"10.1016\/j.microc.2022.107898","article-title":"The fabrication of a flexible and portable sensor based on home-made laser-induced porous graphene electrode for the rapid detection of sulfonamides","volume":"182","author":"Zeng","year":"2022","journal-title":"Microchem. J."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"122920","DOI":"10.1016\/j.talanta.2021.122920","article-title":"Lanthanide metal-organic framework as a paper strip sensor for visual detection of sulfonamide with smartphone-based point-of-care platform","volume":"237","author":"Yan","year":"2022","journal-title":"Talanta"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"135081","DOI":"10.1016\/j.foodchem.2022.135081","article-title":"A reliable upconversion nanoparticle-based immunochromatographic assay for the highly sensitive determination of olaquindox in fish muscle and water samples","volume":"406","author":"Wen","year":"2023","journal-title":"Food Chem."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/28\/8\/3391\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:14:24Z","timestamp":1760123664000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/28\/8\/3391"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,12]]},"references-count":37,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,4]]}},"alternative-id":["molecules28083391"],"URL":"https:\/\/doi.org\/10.3390\/molecules28083391","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,12]]}}}