{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T21:59:47Z","timestamp":1778018387990,"version":"3.51.4"},"reference-count":32,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2023,6,27]],"date-time":"2023-06-27T00:00:00Z","timestamp":1687824000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Major Science and Technology Project of Hebei Province","award":["22282801Z"],"award-info":[{"award-number":["22282801Z"]}]},{"name":"Major Science and Technology Project of Hebei Province","award":["22208236"],"award-info":[{"award-number":["22208236"]}]},{"name":"Major Science and Technology Project of Hebei Province","award":["202204"],"award-info":[{"award-number":["202204"]}]},{"name":"National Natural Science Foundation of China Youth Foundation","award":["22282801Z"],"award-info":[{"award-number":["22282801Z"]}]},{"name":"National Natural Science Foundation of China Youth Foundation","award":["22208236"],"award-info":[{"award-number":["22208236"]}]},{"name":"National Natural Science Foundation of China Youth Foundation","award":["202204"],"award-info":[{"award-number":["202204"]}]},{"name":"2019 Taishan Industry Leading Talents (Strategic Emerging Industry Innovation Category)","award":["22282801Z"],"award-info":[{"award-number":["22282801Z"]}]},{"name":"2019 Taishan Industry Leading Talents (Strategic Emerging Industry Innovation Category)","award":["22208236"],"award-info":[{"award-number":["22208236"]}]},{"name":"2019 Taishan Industry Leading Talents (Strategic Emerging Industry Innovation Category)","award":["202204"],"award-info":[{"award-number":["202204"]}]},{"name":"Opening Project of Zhejiang Engineering Research Center of Fat-soluble Vitamin","award":["22282801Z"],"award-info":[{"award-number":["22282801Z"]}]},{"name":"Opening Project of Zhejiang Engineering Research Center of Fat-soluble Vitamin","award":["22208236"],"award-info":[{"award-number":["22208236"]}]},{"name":"Opening Project of Zhejiang Engineering Research Center of Fat-soluble Vitamin","award":["202204"],"award-info":[{"award-number":["202204"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>The solubility of thiamine nitrate in {(methanol, acetone, isopropanol) + water} solvents will provide essential support for crystallization design and further theoretical studies. In this study, the solubility was experimentally measured over temperatures ranging from 278.15 to 313.15 K under atmospheric pressure using a dynamic method. The solubility increased with increasing temperature at a constant solvent composition. The dissolving capacity of thiamine nitrate in the three binary solvent mixtures at constant temperature in the low ratio of water ranked as water + methanol &gt; water + acetone &gt; water + isopropanol generally. Interestingly, in the high ratio of water systems, especially when the molar concentration of water was greater than 0.6, the dissolving capacity ranked as water + acetone &gt; water + methanol &gt; water + isopropanol. Additionally, the modified Apelblat equation, \u03bbh equation, van\u2019t Hoff equation and NRTL model were used to correlate the solubility data in binary mixtures. It turned out that all the selected thermodynamic models could give satisfactory results. Furthermore, the thermodynamic properties of the dissolution process of thiamine nitrate were also calculated based on the modified van\u2019t Hoff equation. The results indicate that the dissolution process of the thiamine nitrate in the selected solvents is all endothermic.<\/jats:p>","DOI":"10.3390\/molecules28135012","type":"journal-article","created":{"date-parts":[[2023,6,27]],"date-time":"2023-06-27T02:11:22Z","timestamp":1687831882000},"page":"5012","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Measurement and Correlation of Solubility of Thiamine Nitrate in Three Binary Solvents and Thermodynamic Properties for the Solutions in Different Binary Mixtures at (278.15\u2013313.15) K"],"prefix":"10.3390","volume":"28","author":[{"given":"Xinda","family":"Li","sequence":"first","affiliation":[{"name":"State Key Laboratory of Chemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengjiang","family":"Wang","sequence":"additional","affiliation":[{"name":"Xi\u2019an TPRI Water-Management & Environmental Protection Co., Ltd., Xi\u2019an 710054, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"Xi\u2019an TPRI Water-Management & Environmental Protection Co., Ltd., Xi\u2019an 710054, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaqi","family":"Lu","sequence":"additional","affiliation":[{"name":"Xi\u2019an TPRI Water-Management & Environmental Protection Co., Ltd., Xi\u2019an 710054, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Mao","sequence":"additional","affiliation":[{"name":"Xi\u2019an TPRI Water-Management & Environmental Protection Co., Ltd., Xi\u2019an 710054, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dandan","family":"Han","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kangli","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Shaoxing, Tianjin University, Shaoxing 312300, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,27]]},"reference":[{"key":"ref_1","unstructured":"McDowell, L. 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