{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T07:26:15Z","timestamp":1780385175712,"version":"3.54.1"},"reference-count":110,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T00:00:00Z","timestamp":1693958400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>The chemical nature of intracellular labile iron pools (LIPs) is described. By virtue of the kinetic lability of these pools, it is suggested that the isolation of such species by chromatography methods will not be possible, but rather mass spectrometric techniques should be adopted. Iron-sensitive fluorescent probes, which have been developed for the detection and quantification of LIP, are described, including those specifically designed to monitor cytosolic, mitochondrial, and lysosomal LIPs. The potential of near-infrared (NIR) probes for in vivo monitoring of LIP is discussed.<\/jats:p>","DOI":"10.3390\/molecules28186467","type":"journal-article","created":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T10:23:42Z","timestamp":1693995822000},"page":"6467","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Optical Imaging Opportunities to Inspect the Nature of Cytosolic Iron Pools"],"prefix":"10.3390","volume":"28","author":[{"given":"Robert Charles","family":"Hider","sequence":"first","affiliation":[{"name":"Institute of Pharmaceutical Science, King\u2019s College London, London SE1 9NH, UK"},{"name":"Department of Life Sciences, University of Bath, Bath BA2 7AY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charareh","family":"Pourzand","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, University of Bath, Bath BA2 7AY, UK"},{"name":"Centre for Therapeutic Innovation, University of Bath, Bath BA2 7AY, UK"},{"name":"Centre for Bioengineering and Biomedical Technologies, University of Bath, Bath BA2 7AY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongmin","family":"Ma","sequence":"additional","affiliation":[{"name":"Institute of Advanced Studies, School of Pharmaceutical and Chemical Engineering, Taizhou University, 1139 Shifu Avenue, Taizhou 318000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9711-5183","authenticated-orcid":false,"given":"Agostino","family":"Cilibrizzi","sequence":"additional","affiliation":[{"name":"Institute of Pharmaceutical Science, King\u2019s College London, London SE1 9NH, UK"},{"name":"Centre for Therapeutic Innovation, University of Bath, Bath BA2 7AY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Maret, W., and Wedd, A. 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