{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T20:10:47Z","timestamp":1778271047582,"version":"3.51.4"},"reference-count":56,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T00:00:00Z","timestamp":1702857600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Key Laboratory of Kiwifruit Resources Development and Utilization of Guizhou Universities","award":["Qian Jiaoji [2022] 054"],"award-info":[{"award-number":["Qian Jiaoji [2022] 054"]}]},{"name":"Key Laboratory of Kiwifruit Resources Development and Utilization of Guizhou Universities","award":["LPSSYYlzy2003"],"award-info":[{"award-number":["LPSSYYlzy2003"]}]},{"name":"Key Laboratory of Kiwifruit Resources Development and Utilization of Guizhou Universities","award":["LPSSY2023XKTD09"],"award-info":[{"award-number":["LPSSY2023XKTD09"]}]},{"name":"Key Laboratory of Kiwifruit Resources Development and Utilization of Guizhou Universities","award":["Lpssyzxxm202304"],"award-info":[{"award-number":["Lpssyzxxm202304"]}]},{"name":"Key Laboratory of Kiwifruit Resources Development and Utilization of Guizhou Universities","award":["LPSSYKYJJ201601"],"award-info":[{"award-number":["LPSSYKYJJ201601"]}]},{"name":"Key Laboratory of Kiwifruit Resources Development and Utilization of Guizhou Universities","award":["52020-2020-0906"],"award-info":[{"award-number":["52020-2020-0906"]}]},{"name":"Liupanshui Normal University","award":["Qian Jiaoji [2022] 054"],"award-info":[{"award-number":["Qian Jiaoji [2022] 054"]}]},{"name":"Liupanshui Normal University","award":["LPSSYYlzy2003"],"award-info":[{"award-number":["LPSSYYlzy2003"]}]},{"name":"Liupanshui Normal University","award":["LPSSY2023XKTD09"],"award-info":[{"award-number":["LPSSY2023XKTD09"]}]},{"name":"Liupanshui Normal University","award":["Lpssyzxxm202304"],"award-info":[{"award-number":["Lpssyzxxm202304"]}]},{"name":"Liupanshui Normal University","award":["LPSSYKYJJ201601"],"award-info":[{"award-number":["LPSSYKYJJ201601"]}]},{"name":"Liupanshui Normal University","award":["52020-2020-0906"],"award-info":[{"award-number":["52020-2020-0906"]}]},{"name":"Science and Technology project of Liupanshui City","award":["Qian Jiaoji [2022] 054"],"award-info":[{"award-number":["Qian Jiaoji [2022] 054"]}]},{"name":"Science and Technology project of Liupanshui City","award":["LPSSYYlzy2003"],"award-info":[{"award-number":["LPSSYYlzy2003"]}]},{"name":"Science and Technology project of Liupanshui City","award":["LPSSY2023XKTD09"],"award-info":[{"award-number":["LPSSY2023XKTD09"]}]},{"name":"Science and Technology project of Liupanshui City","award":["Lpssyzxxm202304"],"award-info":[{"award-number":["Lpssyzxxm202304"]}]},{"name":"Science and Technology project of Liupanshui City","award":["LPSSYKYJJ201601"],"award-info":[{"award-number":["LPSSYKYJJ201601"]}]},{"name":"Science and Technology project of Liupanshui City","award":["52020-2020-0906"],"award-info":[{"award-number":["52020-2020-0906"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Urinary tract infection is an infectious disease that requires immediate treatment. It can occur in any age group and involves both genders equally. The present study was to check the resistance of some antibiotics and to assess the antibacterial potential of three extracts of three plants against notorious bacteria involved in urinary tract infections. Along with assessing the antibacterial activity of plant extracts, we checked for the anticancer potential of these extracts against the cancer cell lines MCF-7 and A2780. Cancer is the leading cause of mortality in developed countries. Determinations of total flavonoid content, total phenolic content, total alkaloid content, total tannin content, total carotenoid content, and total steroid content were performed. The disk diffusion method was used to analyze the antibacterial activity of plant extracts. Ethanolic extract of Selenicereus undatus showed sensitivity (25\u201328 mm) against bacteria, whereas chloroform and hexane extracts showed resistance against all bacteria except Staphylococcus (25 mm). Ethanolic extract of Pistacia vera L. showed sensitivity (22\u201325 mm) against bacteria, whereas chloroform and hexane extracts showed resistance. Ethanolic extract of Olea europaea L. showed sensitivity (8\u201316 mm) against all bacteria except Staphylococcus, whereas chloroform and hexane extracts showed resistance. Positive controls showed variable zones of inhibition (2\u201360 mm), and negative control showed 0\u20131 mm. The antibiotic resistance was much more prominent in the case of hexane and chloroform extracts of all plants, whereas ethanolic extract showed a sensitivity of bacteria against extracts. Both cell lines, MCF-7 and A2780, displayed decreased live cells when treated with plant extracts.<\/jats:p>","DOI":"10.3390\/molecules28248148","type":"journal-article","created":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T11:28:07Z","timestamp":1702898887000},"page":"8148","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Probing Antibacterial and Anticancer Potential of Selenicereus undatus, Pistacia vera L. and Olea europaea L. against Uropathogens, MCF-7 and A2780 Cancer Cells"],"prefix":"10.3390","volume":"28","author":[{"given":"Sahar","family":"Safdar","sequence":"first","affiliation":[{"name":"School of Biological Sciences and Technology, Liupanshui Normal University, Liupanshui 553004, China"},{"name":"Institute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore 54000, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9147-6316","authenticated-orcid":false,"given":"Saba","family":"Shamim","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore 54000, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8011-7951","authenticated-orcid":false,"given":"Maryam","family":"Khan","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore 54000, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Imran","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore 54000, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mudassar Ali","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Physiology, Rashid Latif Medical College, Lahore 54000, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3160-4830","authenticated-orcid":false,"given":"Qurban","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Plant Breeding and Genetics, Faculty of Agricultural Sciences, University of the Punjab, Lahore 54590, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiming","family":"Han","sequence":"additional","affiliation":[{"name":"School of Biological Sciences and Technology, Liupanshui Normal University, Liupanshui 553004, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,12,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"113592","DOI":"10.1016\/j.jep.2020.113592","article-title":"A review of the phytochemical, pharmacological, pharmacokinetic, and toxicological evaluation of Quercus infectoria galls","volume":"273","author":"Elham","year":"2021","journal-title":"J. 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