{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:58:56Z","timestamp":1791565136994,"version":"4.3.4"},"reference-count":126,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,3,3]],"date-time":"2024-03-03T00:00:00Z","timestamp":1709424000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Educational Department of Liaoning Province","award":["LJKZ0417"],"award-info":[{"award-number":["LJKZ0417"]}]},{"name":"Educational Department of Liaoning Province","award":["2023JH2\/101300238"],"award-info":[{"award-number":["2023JH2\/101300238"]}]},{"name":"Department of Science and Technology of Liaoning Province","award":["LJKZ0417"],"award-info":[{"award-number":["LJKZ0417"]}]},{"name":"Department of Science and Technology of Liaoning Province","award":["2023JH2\/101300238"],"award-info":[{"award-number":["2023JH2\/101300238"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Currently, the alteration of external factors during crude oil extraction easily disrupts the thermodynamic equilibrium of asphaltene, resulting in the continuous flocculation and deposition of asphaltene molecules in crude oil. This accumulation within the pores of reservoir rocks obstructs the pore throat, hindering the efficient extraction of oil and gas, and consequently, affecting the recovery of oil and gas resources. Therefore, it is crucial to investigate the principles of asphaltene deposition inhibition and the synthesis of asphaltene inhibitors. In recent years, the development of nanotechnology has garnered significant attention due to its unique surface and volume effects. Nanoparticles possess a large specific surface area, high adsorption capacity, and excellent suspension and catalytic abilities, exhibiting unparalleled advantages compared with traditional organic asphaltene inhibitors, such as sodium dodecyl benzene sulfonate and salicylic acid. At present, there are three primary types of nanoparticle inhibitors: metal oxide nanoparticles, organic nanoparticles, and inorganic nonmetal nanoparticles. This paper reviews the recent advancements and application challenges of nanoparticle asphaltene deposition inhibition technology based on the mechanism of asphaltene deposition and nano-inhibitors. The aim was to provide insights for ongoing research in this field and to identify potential future research directions.<\/jats:p>","DOI":"10.3390\/molecules29051135","type":"journal-article","created":{"date-parts":[[2024,3,4]],"date-time":"2024-03-04T04:36:21Z","timestamp":1709526981000},"page":"1135","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Research Progress in Nanoparticle Inhibitors for Crude Oil Asphaltene Deposition"],"prefix":"10.3390","volume":"29","author":[{"given":"Shuangchun","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Petroleum and Natural Gas Engineering College, Liaoning Petrochemical University, No.1, West Section of Dandong Road, Wanghua District, Fushun 113001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenhui","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Petroleum and Natural Gas Engineering College, Liaoning Petrochemical University, No.1, West Section of Dandong Road, Wanghua District, Fushun 113001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiatie","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Petroleum and Natural Gas Engineering College, Liaoning Petrochemical University, No.1, West Section of Dandong Road, Wanghua District, Fushun 113001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Petroleum and Natural Gas Engineering College, Liaoning Petrochemical University, No.1, West Section of Dandong Road, Wanghua District, Fushun 113001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuju","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Petrochemical Engineering College, Liaoning Petrochemical University, No.1, West Section of Dandong Road, Wanghua District, Fushun 113001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,3]]},"reference":[{"key":"ref_1","first-page":"88","article-title":"Research on Asphaltene Inhibitors in Halahatang Oilfield","volume":"23","author":"He","year":"2016","journal-title":"Petrochem. 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