{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:27:49Z","timestamp":1792092469730,"version":"4.4.0"},"reference-count":65,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T00:00:00Z","timestamp":1715212800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Regional Development Fund-the Competitiveness and Cohesion Operational Pro-gramme","award":["KK.01.1.1.01"],"award-info":[{"award-number":["KK.01.1.1.01"]}]},{"name":"European Regional Development Fund-the Competitiveness and Cohesion Operational Pro-gramme","award":["KK.01.1.1.01.0002"],"award-info":[{"award-number":["KK.01.1.1.01.0002"]}]},{"name":"project Bioprospecting of the Adriatic Sea","award":["KK.01.1.1.01"],"award-info":[{"award-number":["KK.01.1.1.01"]}]},{"name":"project Bioprospecting of the Adriatic Sea","award":["KK.01.1.1.01.0002"],"award-info":[{"award-number":["KK.01.1.1.01.0002"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>In this paper, the preparation of three new polysaccharide-type chiral stationary phases (CSPs) based on levan carbamates (3,5-dimethylphenyl, 4-methylphenyl, and 1-naphthyl) is described. The enantioseparation of (\u00b1)-trans-\u03b2-lactam ureas 1a\u2013h was investigated by high-performance liquid chromatography (HPLC) on six different chiral columns (Chiralpak AD-3, Chiralcel OD-3, Chirallica PST-7, Chirallica PST-8, Chirallica PST-9, and Chirallica PST-10) in the polar organic mode, using pure methanol (MeOH), ethanol (EtOH), and acetonitrile (ACN). Apart from the Chirallica PST-9 column (based on levan tris(1-naphthylcarbamate), the columns exhibited a satisfactory chiral recognition ability for the tested trans-\u03b2-lactam ureas 1a\u2013h.<\/jats:p>","DOI":"10.3390\/molecules29102213","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T03:34:19Z","timestamp":1715225659000},"page":"2213","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["New Levan-Based Chiral Stationary Phases: Synthesis and Comparative HPLC Enantioseparation of (\u00b1)-trans-\u03b2-Lactam Ureas in the Polar Organic Mode"],"prefix":"10.3390","volume":"29","author":[{"given":"Darko","family":"Kontrec","sequence":"first","affiliation":[{"name":"Laboratory for Chiral Technologies, Division of Organic Chemistry and Biochemistry, Ruder Bo\u0161kovi\u0107 Institute, Bijeni\u010dka Cesta 54, 10 000 Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5587-4843","authenticated-orcid":false,"given":"Mladenka","family":"Jurin","sequence":"additional","affiliation":[{"name":"Laboratory for Chiral Technologies, Division of Organic Chemistry and Biochemistry, Ruder Bo\u0161kovi\u0107 Institute, Bijeni\u010dka Cesta 54, 10 000 Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6095-7515","authenticated-orcid":false,"given":"Andreja","family":"Jakas","sequence":"additional","affiliation":[{"name":"Laboratory for Chiral Technologies, Division of Organic Chemistry and Biochemistry, Ruder Bo\u0161kovi\u0107 Institute, Bijeni\u010dka Cesta 54, 10 000 Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7478-1490","authenticated-orcid":false,"given":"Marin","family":"Roje","sequence":"additional","affiliation":[{"name":"Laboratory for Chiral Technologies, Division of Organic Chemistry and Biochemistry, Ruder Bo\u0161kovi\u0107 Institute, Bijeni\u010dka Cesta 54, 10 000 Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2743","DOI":"10.1002\/elps.200800685","article-title":"Enantiomeric separation by MEKC using dodecyl thioglycoside surfactants: Importance of an equatorially oriented hydroxy group at C-2 position in separation of dansylated amino acids","volume":"30","author":"Tano","year":"2009","journal-title":"Electrophoresis"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.trac.2014.10.009","article-title":"Recent development of cationic cyclodextrins for chiral separation","volume":"65","author":"Zhou","year":"2015","journal-title":"TrAC Trends Anal. 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