{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:58:20Z","timestamp":1787029100506,"version":"build-2736575974"},"reference-count":31,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T00:00:00Z","timestamp":1728518400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>A novel and controllable synthesis of thioacetals\/thioketals and \u03b2-sulfanyl ketones mediated by the reaction of aldehyde\/acetone with thiols has been developed. In this protocol, \u03b2-sulfanyl ketones can be generated without the prior preparation of \u03b1, \u03b2-unsaturated carbonyl compounds. A variety of thiols reacted with aldehyde\/acetone and provided the corresponding thioacetals\/thioketals and \u03b2-sulfanyl ketones in good to excellent yields, respectively. This protocol is operationally simple, mild, and atom-economical, providing controllable access to thioacetals\/thioketals and thia-Michael addition products under mild conditions.<\/jats:p>","DOI":"10.3390\/molecules29204785","type":"journal-article","created":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T07:54:09Z","timestamp":1728546849000},"page":"4785","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Controllable Synthesis of Thioacetals\/Thioketals and \u03b2-Sulfanyl Ketones Mediated by Methanesulfonic Anhydride and Sulfuric Acid Sulfuric Acid from Aldehyde\/Acetone and Thiols"],"prefix":"10.3390","volume":"29","author":[{"given":"Hexia","family":"Ye","sequence":"first","affiliation":[{"name":"State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyao","family":"Zhao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajie","family":"Fu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China"},{"name":"School of Chemistry and Environmental Engineering, Sichuan University of Science &Engineering, 180 Xueyuan Street, Huixing Lu, Zigong 643000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibo","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junchen","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Bi","sequence":"additional","affiliation":[{"name":"State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4208","DOI":"10.1039\/C4CC09633A","article-title":"Transition-metal-free persulfuration to construct unsymmetrical disulfides and mechanistic study of the sulfur redox process","volume":"51","author":"Xiao","year":"2015","journal-title":"Chem. 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