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However, traditional medications for repairing skin photoaging cause side effects. Natural bioactive compounds have been shown to prevent and treat skin photoaging with fewer side effects. Epigallocatechin gallate (EGCG), the main substance in tea polyphenols, is a natural bioactive compound with a range of properties. This review summarizes the beneficial effects and mechanisms of EGCG, as well as the application forms of EGCG in repairing photoaged skin. Results indicated that EGCG has repair effects, including improving elasticity, enhancing moisturization, inhibiting damage, and reducing pigmentation of photoaged skin. It has also been demonstrated that EGCG delivery systems, modified EGCG, and combinations with other bioactive substances could be used for repairing photoaged skin due to its poor stability and low bioavailability. EGCG effectively repairs various types of skin damage caused by UV radiation while maintaining normal skin structure and function. It is, therefore, an effective candidate for repairing photoaged skin. These results could provide references for the development and application of EGCG products for the treatment of photoaged skin.<\/jats:p>","DOI":"10.3390\/molecules29225226","type":"journal-article","created":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T06:30:48Z","timestamp":1730788248000},"page":"5226","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Beneficial Effects of Epigallocatechin Gallate in Preventing Skin Photoaging: A Review"],"prefix":"10.3390","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-6459-3283","authenticated-orcid":false,"given":"Jiaqiang","family":"Sun","sequence":"first","affiliation":[{"name":"College of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China"},{"name":"Shaanxi Province Key Laboratory of Bio-Resources, Shaanxi University of Technology, Hanzhong 723001, China"},{"name":"Qinba Mountain Area Collaborative Innovation Center of Bioresources Comprehensive Development, State Key Laboratory of Biological Resources and Ecological Environment (Incubation), Hanzhong 723001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuelu","family":"Jiang","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Fu","sequence":"additional","affiliation":[{"name":"College of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China"},{"name":"Shaanxi Province Key Laboratory of Bio-Resources, Shaanxi University of Technology, Hanzhong 723001, China"},{"name":"Qinba Mountain Area Collaborative Innovation Center of Bioresources Comprehensive Development, State Key Laboratory of Biological Resources and Ecological Environment (Incubation), Hanzhong 723001, China"},{"name":"Key Laboratory of Special Economic Animal and Plant Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7569-6397","authenticated-orcid":false,"given":"Linlin","family":"He","sequence":"additional","affiliation":[{"name":"College of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China"},{"name":"Shaanxi Province Key Laboratory of Bio-Resources, Shaanxi University of Technology, Hanzhong 723001, China"},{"name":"Qinba Mountain Area Collaborative Innovation Center of Bioresources Comprehensive Development, State Key Laboratory of Biological Resources and Ecological Environment (Incubation), Hanzhong 723001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinmiao","family":"Guo","sequence":"additional","affiliation":[{"name":"College of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Ye","sequence":"additional","affiliation":[{"name":"College of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuiyuan","family":"Yin","sequence":"additional","affiliation":[{"name":"College of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbo","family":"Li","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3101-7951","authenticated-orcid":false,"given":"Heyuan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Special Economic Animal and Plant Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s13671-020-00288-0","article-title":"Photoaging: A Review of Current Literature","volume":"9","author":"Huang","year":"2020","journal-title":"Curr. 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