{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T22:25:13Z","timestamp":1790202313027,"version":"4.1.0"},"reference-count":40,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T00:00:00Z","timestamp":1731024000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007652","name":"Instituto Nacional de Investigaci\u00f3n y Tecnolog\u00eda Agraria y Alimentaria","doi-asserted-by":"publisher","award":["RTA2017-00031-C43"],"award-info":[{"award-number":["RTA2017-00031-C43"]}],"id":[{"id":"10.13039\/100007652","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Plants of the Lamiaceae family are widely used for the extraction of essential oils, and this industry generates a large number of solid residues as by-products, which contain non-volatile valuable compounds. The aim of this work was to identify and quantify the phenolic compounds present in these solid residues from different important Spanish species of Lamiaceae to characterize and valorize them. Forty-seven phenolic compounds were identified by HPLC-DAD-MS and quantified by HPLC-DAD. Different concentrations and types of phenolic compounds were found between the solid residues. The Rosmarinus officinalis extracts showed the highest total phenolic content due to their high phenolic terpene concentrations. The Thymus\u00a0mastichina extracts were characterized by kaempferol and flavanones, and some flavones were derived from luteolin and apigenin. Finally, the sample Lavandula and Salvia lavandulifolia extracts presented the lowest content of most phenolic compounds, with the exception of some phenolic acids, such as danshensu, salvianolic acid A, and glucosides of hydroxycinnamic acids. Therefore, this work provides information on the quantification of a large number of phenolic compounds using a simple, sensitive, reproducible, and accurate methodology. In addition, the results indicate that these solid residues still contain important amounts of different polyphenols, which are antioxidants and can be used in different industries.<\/jats:p>","DOI":"10.3390\/molecules29225285","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T03:53:14Z","timestamp":1731383594000},"page":"5285","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Characterization of Bioactive Phenolic Compounds Extracted from Hydro-Distillation By-Products of Spanish Lamiaceae Plants"],"prefix":"10.3390","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0880-7154","authenticated-orcid":false,"given":"Silvia","family":"P\u00e9rez-Magari\u00f1o","sequence":"first","affiliation":[{"name":"Agrarian Technological Institute of Castilla and Le\u00f3n, Consejer\u00eda de Agricultura y Ganader\u00eda, Ctra Burgos Km 119, Finca Zamadue\u00f1as, 47071 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8711-534X","authenticated-orcid":false,"given":"Marta","family":"Bueno-Herrera","sequence":"additional","affiliation":[{"name":"Agrarian Technological Institute of Castilla and Le\u00f3n, Consejer\u00eda de Agricultura y Ganader\u00eda, Ctra Burgos Km 119, Finca Zamadue\u00f1as, 47071 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3872-463X","authenticated-orcid":false,"given":"M. Carmen","family":"Asensio-S.-Manzanera","sequence":"additional","affiliation":[{"name":"Agrarian Technological Institute of Castilla and Le\u00f3n, Consejer\u00eda de Agricultura y Ganader\u00eda, Ctra Burgos Km 119, Finca Zamadue\u00f1as, 47071 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s12231-022-09554-7","article-title":"A new global estimation of medicinal and aromatic plant species in commercial cultivation and their conservation status","volume":"76","author":"Brinckmann","year":"2022","journal-title":"Econ. Bot."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Taghouti, I., Cristobal, R., Brenko, A., Stara, K., Markos, N., Chapelet, B., Hamrouni, L., Bursic, D., and Bonet, J.A. (2022). 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