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Their structures were elucidated by HESI-HRMS\/MS and one- and two-dimensional nuclear magnetic resonance (NMR) spectroscopy. This is the first study identifying A1\u2013A5 in A. altissima tree. Except for A5, all isolated compounds exhibited antibacterial activity against B. subtilis in microdilution assays. A6 showed the strongest effect with a minimum inhibitory concentration (MIC) value of 8.3 \u00b5g\/mL. The antibacterial activity of A3 and A4 is newly described.<\/jats:p>","DOI":"10.3390\/molecules29245846","type":"journal-article","created":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T12:58:49Z","timestamp":1733921929000},"page":"5846","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Bioassay-Guided Isolation and Identification of Antibacterial Compounds from Invasive Tree of Heaven Stem and Trunk Bark"],"prefix":"10.3390","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-9138-8326","authenticated-orcid":false,"given":"Anna","family":"Csel\u0151tey","sequence":"first","affiliation":[{"name":"Plant Protection Institute, HUN-REN Centre for Agricultural Research, Feh\u00e9rv\u00e1ri \u00fat 132\u2013144, 1116 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0385-6835","authenticated-orcid":false,"given":"M\u00e1rton","family":"Baglyas","sequence":"additional","affiliation":[{"name":"Plant Protection Institute, HUN-REN Centre for Agricultural Research, Feh\u00e9rv\u00e1ri \u00fat 132\u2013144, 1116 Budapest, Hungary"},{"name":"Doctoral School, Semmelweis University, \u00dcll\u0151i \u00fat 26, 1085 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00f3ra","family":"Kir\u00e1ly","sequence":"additional","affiliation":[{"name":"Plant Protection Institute, HUN-REN Centre for Agricultural Research, Feh\u00e9rv\u00e1ri \u00fat 132\u2013144, 1116 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter G.","family":"Ott","sequence":"additional","affiliation":[{"name":"Plant Protection Institute, HUN-REN Centre for Agricultural Research, Feh\u00e9rv\u00e1ri \u00fat 132\u2013144, 1116 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0766-0266","authenticated-orcid":false,"given":"Vesna","family":"Glavnik","sequence":"additional","affiliation":[{"name":"Laboratory for Food Chemistry, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4738-2849","authenticated-orcid":false,"given":"Irena","family":"Vovk","sequence":"additional","affiliation":[{"name":"Laboratory for Food Chemistry, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4330-9396","authenticated-orcid":false,"given":"\u00c1gnes M.","family":"M\u00f3ricz","sequence":"additional","affiliation":[{"name":"Plant Protection Institute, HUN-REN Centre for Agricultural Research, Feh\u00e9rv\u00e1ri \u00fat 132\u2013144, 1116 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.mib.2019.10.008","article-title":"Antibiotics: Past, Present and Future","volume":"51","author":"Hutchings","year":"2019","journal-title":"Curr. 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