{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T14:18:48Z","timestamp":1791555528184,"version":"4.3.4"},"reference-count":83,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Research Project for Universities in Xinjiang Uygur Autonomous Region","award":["JEDU2024P050"],"award-info":[{"award-number":["JEDU2024P050"]}]},{"name":"Research Project for Universities in Xinjiang Uygur Autonomous Region","award":["20222943"],"award-info":[{"award-number":["20222943"]}]},{"name":"Research Project for Universities in Xinjiang Uygur Autonomous Region","award":["2024B03017"],"award-info":[{"award-number":["2024B03017"]}]},{"name":"talent funding project of Xinjiang Medical University","award":["JEDU2024P050"],"award-info":[{"award-number":["JEDU2024P050"]}]},{"name":"talent funding project of Xinjiang Medical University","award":["20222943"],"award-info":[{"award-number":["20222943"]}]},{"name":"talent funding project of Xinjiang Medical University","award":["2024B03017"],"award-info":[{"award-number":["2024B03017"]}]},{"name":"Key Research and Development Program of Xinjiang","award":["JEDU2024P050"],"award-info":[{"award-number":["JEDU2024P050"]}]},{"name":"Key Research and Development Program of Xinjiang","award":["20222943"],"award-info":[{"award-number":["20222943"]}]},{"name":"Key Research and Development Program of Xinjiang","award":["2024B03017"],"award-info":[{"award-number":["2024B03017"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Juniperus sabina L., a species within the Juniperus genus, is broadly distributed across Southern Europe and Central Asia. In China, its berries, branches, and leaves are traditionally employed in Uyghur medicine to address conditions such as rheumatoid arthritis, itchy skin, tinnitus, deafness, and urinary discomfort. Notably, the plant\u2019s primary bioactive constituents are terpenoids, lignans, and flavonoids. Contemporary pharmacological studies have revealed that J. sabina exhibits a range of bioactivities, including insecticidal, antimicrobial, antioxidant, anti-inflammatory, and antitumor effects. These diverse therapeutic properties can be attributed to its rich chemical profile, which comprises 279 distinct compounds such as terpenoids, lignans, flavonoids, coumarins, and others, isolated to date. This comprehensive review systematically organizes and summarizes the botanical characteristics, traditional uses, chemical composition, pharmacological activities, toxicity, limitations, and future prospects of J. sabina. It aims to offer a valuable scientific reference and fresh perspectives for further research, development, and application of this plant.<\/jats:p>","DOI":"10.3390\/molecules29245876","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T12:25:54Z","timestamp":1734006354000},"page":"5876","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Phytochemistry, Pharmacology, and Traditional Medicine Applications of Juniperus sabina L.: A Comprehensive Overview"],"prefix":"10.3390","volume":"29","author":[{"given":"Lan","family":"Pan","sequence":"first","affiliation":[{"name":"College of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi 830017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyuan","family":"Zhou","sequence":"additional","affiliation":[{"name":"College of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi 830017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Chen","sequence":"additional","affiliation":[{"name":"Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyan","family":"Xu","sequence":"additional","affiliation":[{"name":"College of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi 830017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenli","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Nantong University, Nantong 226000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"key":"ref_1","first-page":"281","article-title":"Evaluation of in vitro cytotoxic effects of Juniperus foetidissima and Juniperus sabina extracts against a panel of cancer cells","volume":"8","author":"Emami","year":"2009","journal-title":"Iran. 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