{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T21:21:00Z","timestamp":1793481660582,"version":"4.5.0"},"reference-count":51,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T00:00:00Z","timestamp":1734048000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Natural Science Foundation of China","award":["22304030"],"award-info":[{"award-number":["22304030"]}]},{"name":"National Natural Science Foundation of China","award":["22478164"],"award-info":[{"award-number":["22478164"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>With the development and improvement of analysis and detection systems, low-toxicity and harmless detection systems have received much attention, especially in the field of food detection. In this paper, a low-toxicity dual-emission molecularly imprinted fluorescence sensor (CdTe QDs@SiO2\/N-CDs@MIPs) was successfully designed for highly selective recognition and visual detection of tetracycline (TC) in food samples. Specifically, the non-toxic blue-emission N-doped carbon dots (N-CDs) with high luminous performance acted as the response signals to contact TC via the covalent bond between amino and carboxyl groups. The red-emission CdTe quantum dots (CdTe QDs) were coated in silica nanospheres as stable reference signals, which effectively avoided the direct contact of CdTe QDs. Under optimum conditions, CdTe QDs@SiO2\/N-CDs@MIPs had a rapid response within 1.0 min to TC, and the detection limit of CdTe QDs@SiO2\/N-CDs@MIPs was calculated at 0.846 \u03bcM in the linear range of 0\u2013140 \u03bcM. In complex environments, the CdTe QDs@SiO2\/N-CDs@MIPs also exhibited excellent capabilities for the selective, rapid, and visual detection of TC. Furthermore, the accuracy of CdTe QDs@SiO2\/N-CDs@MIPs to detect TC was verified by the HPLC method, and satisfactory results were obtained. Moreover, CdTe QDs@SiO2\/N-CDs@MIPs showed a satisfactory recovery when measuring TC in milk and egg samples. This work provided an ideal approach for low-toxicity fluorescence sensor design and application.<\/jats:p>","DOI":"10.3390\/molecules29245888","type":"journal-article","created":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T05:55:45Z","timestamp":1734069345000},"page":"5888","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Low-Toxicity and High-Stability Fluorescence Sensor for the Selective, Rapid, and Visual Detection Tetracycline in Food Samples"],"prefix":"10.3390","volume":"29","author":[{"given":"Jixiang","family":"Wang","sequence":"first","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaowei","family":"Qin","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Ma","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minjia","family":"Meng","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeqing","family":"Xu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Molecular Engineering of Polymers, Laboratory of Advanced Materials, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai 200438, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"129501","DOI":"10.1016\/j.foodchem.2021.129501","article-title":"A portable test strip based on fluorescent europium-based metal-organic framework for rapid and visual detection of tetracycline in food samples","volume":"354","author":"Gan","year":"2021","journal-title":"Food Chem."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"7584","DOI":"10.1021\/acs.jafc.3c00846","article-title":"Ratiometric Sensing for Ultratrace Tetracycline Using Electrochemically Active Metal-Organic Frameworks as Response Signals","volume":"71","author":"Liang","year":"2023","journal-title":"J. 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