{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T19:44:04Z","timestamp":1773085444974,"version":"3.50.1"},"reference-count":67,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T00:00:00Z","timestamp":1749600000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017218","name":"Giresun University","doi-asserted-by":"publisher","award":["Fen-BAP-A-140316-34"],"award-info":[{"award-number":["Fen-BAP-A-140316-34"]}],"id":[{"id":"10.13039\/100017218","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Dispersive liquid\u2013liquid microextraction (DLLME) is an economical, rapid, sensitive, and environmentally friendly miniaturized liquid\u2013liquid extraction format. It has been successfully applied in trace element analysis since 2006 when it was first proposed. This article describes a new dispersive liquid\u2013liquid microextraction method for the determination of trace amounts of Co2+. In brief, this method involves the extraction of Co2+ from the sample to the trichloromethane phase by the dispersive action of methanol after the formation of a complex with a novel 9-(methylaminomethyl)anthracene-Ni(II) phthalocyanine (MAMA Ni(II)Pc 2) as a sensor. The first step in this study was the synthesis and characterisation of the sensor. Later, the proposed method was optimized with respect to various parameters such as extraction and dispersive solvents and their amounts, pH, sensor concentration, and centrifugation time and rate. The calibration graph was linear between 0.40 and 260 \u00b5g\/L, with an R2 of 0.9978. The limit of detection and limit of quantification were found to be 0.19 \u00b5g\/L and 0.46 \u00b5g\/L, respectively. To evaluate the precision of this method, the analysis of a 50 \u00b5g\/L Co2+ solution was carried out. The intra-day and inter-day relative standard deviation values were calculated as 1.7% and 2.4%, respectively (n = 7). The accuracy of the proposed method was investigated by means of a standard addition\/recovery test.<\/jats:p>","DOI":"10.3390\/molecules30122548","type":"journal-article","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T06:11:49Z","timestamp":1749622309000},"page":"2548","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dispersive Liquid\u2013Liquid Microextraction Method Utilizing a Novel Peripherally Tetra-Substituted Ni(II) Phthalocyanine as a Sensor Prior to UV-Visible Spectrophotometry for the Determination of Co2+"],"prefix":"10.3390","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8437-5373","authenticated-orcid":false,"given":"Yasemin","family":"\u00c7a\u011flar","sequence":"first","affiliation":[{"name":"Department of Genetic and Bioengineering, Giresun University, Giresun 28200, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1074-7752","authenticated-orcid":false,"given":"Ece Tu\u011fba","family":"Saka","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Karadeniz Technical University, Trabzon 61080, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"155219","DOI":"10.1016\/j.scitotenv.2022.155219","article-title":"Recent Advances on Rapid Detection and Remediation of Environmental Pollutants Utilizing Nanomaterials-Based (Bio)Sensors","volume":"834","author":"Thakur","year":"2022","journal-title":"Sci. Total Environ."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"120573","DOI":"10.1016\/j.talanta.2019.120573","article-title":"A New Software-Assisted Analytical Workflow Based on High-Resolution Mass Spectrometry for the Systematic Study of Phenolic Compounds in Complex Matrices","volume":"209","author":"Cerrato","year":"2020","journal-title":"Talanta"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"16930","DOI":"10.1007\/s11356-022-24727-6","article-title":"Worldwide Research on Extraction and Recovery of Cobalt through Bibliometric Analysis: A Review","volume":"30","author":"Zhou","year":"2023","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/j.apgeochem.2012.02.001","article-title":"Distribution of Cu, Co, As, and Fe in Mine Waste, Sediment, Soil, and Water in and around Mineral Deposits and Mines of the Idaho Cobalt Belt, USA","volume":"27","author":"Gray","year":"2012","journal-title":"Appl. Geochem."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"236","DOI":"10.5114\/ceji.2015.52837","article-title":"Selected Aspects of the Action of Cobalt Ions in the Human Body","volume":"40","author":"Czarnek","year":"2015","journal-title":"Cent. Eur. J. Immunol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.scitotenv.2012.06.009","article-title":"Cobalt Metabolism and Toxicology\u2014A Brief Update","volume":"432","author":"Simonsen","year":"2012","journal-title":"Sci. Total Environ."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"136606","DOI":"10.1016\/j.foodchem.2023.136606","article-title":"The Importance, Prevalence and Determination of Vitamins B6 and B12 in Food Matrices: A Review","volume":"426","author":"Santos","year":"2023","journal-title":"Food Chem."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"5464373","DOI":"10.1155\/2016\/5464373","article-title":"Nutritional Aspects of Essential Trace Elements in Oral Health and Disease: An Extensive Review","volume":"2016","author":"Bhattacharya","year":"2016","journal-title":"Scientifica"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"6431","DOI":"10.1007\/s13762-018-2052-9","article-title":"Modification of Magnetized MCM-41 by Pyridine Groups for Ultrasonic-Assisted Dispersive Micro-Solid-Phase Extraction of Nickel Ions","volume":"16","author":"Behbahani","year":"2019","journal-title":"Int. J. Environ. Sci. Technol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.foodchem.2015.07.029","article-title":"Simultaneous Spectrophotometric Determination of Copper, Cobalt, Nickel and Iron in Foodstuffs and Vegetables with a New Bis Thiosemicarbazone Ligand Using Chemometric Approaches","volume":"192","author":"Darehkordi","year":"2016","journal-title":"Food Chem."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.foodchem.2019.02.036","article-title":"Determination of Vitamin B12 and Cobalt in Egg Yolk Using Vortex Assisted Switchable Solvent Based Liquid Phase Microextraction Prior to Slotted Quartz Tube Flame Atomic Absorption Spectrometry","volume":"286","author":"Tekin","year":"2019","journal-title":"Food Chem."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.foodchem.2018.12.110","article-title":"Centrifuge-Less Deep Eutectic Solvent Based Magnetic Nanofluid-Linked Air-Agitated Liquid\u2013Liquid Microextraction Coupled with Electrothermal Atomic Absorption Spectrometry for Simultaneous Determination of Cadmium, Lead, Copper, and Arsenic in Food Samples and Non-Alcoholic Beverages","volume":"281","author":"Shirani","year":"2019","journal-title":"Food Chem."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s10812-022-01396-4","article-title":"Ultrasound-Assisted Dispersive Microsolid-Phase Extraction for Preconcentration of Trace Cobalt and Nickel in Environmental Samples Prior to Their Determination by Flame Atomic Absorption Spectrometry","volume":"89","author":"Gouda","year":"2022","journal-title":"J. Appl. Spectrosc."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/j.ijbiomac.2019.09.245","article-title":"Characterization of Natural Gums via Elemental and Chemometric Analyses, Synthesis of Silver Nanoparticles, and Biological and Catalytic Applications","volume":"147","author":"Jamila","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1080\/00032719.2016.1158831","article-title":"Elemental Analysis of Sea, Rock, and Bamboo Salts by Inductively Coupled Plasma-Optical Emission and Mass Spectrometry","volume":"49","author":"Yang","year":"2016","journal-title":"Anal. Lett."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"121485","DOI":"10.1016\/j.talanta.2020.121485","article-title":"Extraction and ICP-OES Determination of Heavy Metals Using Tetrabutylammonium Bromide Aqueous Biphasic System and Oleophilic Collector","volume":"221","author":"Smirnova","year":"2021","journal-title":"Talanta"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1080\/03067319.2013.823487","article-title":"Simultaneous Preconcentration and Determination of Nickel and Cobalt Using Functionalised Mesoporous Silica Spheres by ICP-OES","volume":"93","author":"Sadia","year":"2013","journal-title":"Int. J. Environ. Anal. Chem."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.foodchem.2013.10.002","article-title":"Preconcentration of Heavy Metals on Activated Carbon and Their Determination in Fruits by Inductively Coupled Plasma Optical Emission Spectrometry","volume":"147","author":"Feist","year":"2014","journal-title":"Food Chem."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"104340","DOI":"10.1016\/j.microc.2019.104340","article-title":"Needle Hub In-Syringe Solid Phase Extraction Based a Novel Functionalized Biopolyamide for Simultaneous Green Separation\/Preconcentration and Determination of Cobalt, Nickel, and Chromium (III) in Food and Environmental Samples with Micro Sampling Flame Atomic Absorption Spectrometry","volume":"152","author":"Shirani","year":"2020","journal-title":"Microchem. J."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.molliq.2016.10.005","article-title":"Deep Eutectic Solvent Based Ultrasonic Assisted Liquid Phase Microextraction for the FAAS Determination of Cobalt","volume":"224","author":"Arain","year":"2016","journal-title":"J. Mol. Liq."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.talanta.2013.02.015","article-title":"Determination of Lead and Cadmium Using an Ionic Liquid and Dispersive Liquid-Liquid Microextraction Followed by Electrothermal Atomic Absorption Spectrometry","volume":"110","year":"2013","journal-title":"Talanta"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"28014","DOI":"10.1039\/D1RA03962H","article-title":"Quantification of Nickel, Cobalt, and Manganese Concentration Using Ultraviolet-Visible Spectroscopy","volume":"11","author":"Malik","year":"2021","journal-title":"RSC Adv."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.ijleo.2019.03.056","article-title":"Determination of Trace Ions of Cobalt and Copper by UV\u2013Vis Spectrometry in Purification Process of Zinc Hydrometallurgy","volume":"184","author":"Zhou","year":"2019","journal-title":"Optik"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"\u00dcnald\u0131, M., Y\u0131ld\u0131z, B., and Durukan, \u0130. (2024). Green Surfactant Assisted-Solidified Floating Organic Drop Micro-Extraction for the Preconcentration of Trace Cobalt and Determination by Flame Atomic Absorption Spectrometry. Anal. Lett., 1\u201318.","DOI":"10.1080\/00032719.2024.2437804"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1016\/j.molliq.2017.07.038","article-title":"Development of Effervescence-Assisted Liquid Phase Microextraction Based on Fatty Acid for Determination of Silver and Cobalt Ions Using Micro-Sampling Flame Atomic Absorption Spectrometry","volume":"242","author":"Rajabi","year":"2017","journal-title":"J. Mol. Liq."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"125336","DOI":"10.1016\/j.foodchem.2019.125336","article-title":"An Accurate Determination Method for Cobalt in Sage Tea and Cobalamin: Slotted Quartz Tube-Flame Atomic Absorption Spectrometry after Preconcentration with Switchable Liquid-Liquid Microextraction Using a Schiff Base","volume":"302","year":"2020","journal-title":"Food Chem."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"107150","DOI":"10.1016\/j.microc.2021.107150","article-title":"A Review on Extraction, Preconcentration and Speciation of Metal Ions by Sustainable Cloud Point Extraction","volume":"175","author":"Mandal","year":"2022","journal-title":"Microchem. J."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.chroma.2006.03.007","article-title":"Determination of Organic Compounds in Water Using Dispersive Liquid-Liquid Microextraction","volume":"1116","author":"Rezaee","year":"2006","journal-title":"J. Chromatogr. A"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.jscs.2011.11.005","article-title":"The Recent Developments in Dispersive Liquid-Liquid Microextraction for Preconcentration and Determination of Inorganic Analytes","volume":"18","author":"Emara","year":"2014","journal-title":"J. Saudi Chem. Soc."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"117429","DOI":"10.1016\/j.trac.2023.117429","article-title":"Advancements in Overcoming Challenges in Dispersive Liquid-Liquid Microextraction: An Overview of Advanced Strategies","volume":"170","author":"Faraji","year":"2024","journal-title":"TrAC\u2014Trends Anal. Chem."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"108807","DOI":"10.1016\/j.microc.2023.108807","article-title":"Recent Advances in Dispersion Strategies for Dispersive Liquid\u2013Liquid Microextraction from Green Chemistry Perspectives","volume":"191","author":"Elmansi","year":"2023","journal-title":"Microchem. J."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"106449","DOI":"10.1016\/j.jfca.2024.106449","article-title":"Determination of Trace Amounts of Metobromuron Herbicide Residues in Fruits by QuEChERS and DLLME Methods","volume":"133","author":"Oflu","year":"2024","journal-title":"J. Food Compos. Anal."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"4730","DOI":"10.1039\/C7CS00719A","article-title":"Classic Highlights in Porphyrin and Porphyrinoid Total Synthesis and Biosynthesis","volume":"50","author":"Senge","year":"2021","journal-title":"Chem. Soc. Rev."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"213359","DOI":"10.1016\/j.ccr.2020.213359","article-title":"Recent Advances in Phthalocyanines for Chemical Sensor, Non-Linear Optics (NLO) and Energy Storage Applications","volume":"420","author":"Gounden","year":"2020","journal-title":"Coord. Chem. Rev."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"6184","DOI":"10.1021\/acs.chemrev.5b00588","article-title":"Optically Active Porphyrin and Phthalocyanine Systems","volume":"116","author":"Lu","year":"2016","journal-title":"Chem. Rev."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1142\/S1088424602000336","article-title":"Recent Advances in the Electrochemistry of Porphyrins and Phthalocyanines","volume":"6","author":"Souza","year":"2002","journal-title":"J. Porphyr. Phthalocyanines"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"115479","DOI":"10.1016\/j.poly.2021.115479","article-title":"Double-Decker Lutetium Phthalocyanine Functionalized with 4-Phenylthiazol-2-Thiol Moieties: Synthesis, Characterization, Electrochemistry, Spectroelectrochemistry and Electrochromism","volume":"209","author":"Budak","year":"2021","journal-title":"Polyhedron"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.ica.2007.06.043","article-title":"Synthesis, Electrochemistry and Spectroscopic Properties of Ruthenium Phthalocyanine and Naphthalocyanine Complexes with Triphenylarsine Ligands","volume":"361","author":"Rawling","year":"2008","journal-title":"Inorganica Chim. Acta"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"3699","DOI":"10.1021\/ac9003375","article-title":"Highly Selective Phthalocyanine-Thymine Conjugate Sensor for Hg 2+ Based on Target Induced Aggregation","volume":"81","author":"Liu","year":"2009","journal-title":"Anal. Chem."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/tcr.20139","article-title":"Phthalocyanines: From Outstanding Electronic Properties to Emerging Applications","volume":"8","author":"Claessens","year":"2008","journal-title":"Chem. Rec."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1039\/C9CS00129H","article-title":"The Unique Features and Promises of Phthalocyanines as Advanced Photosensitisers for Photodynamic Therapy of Cancer","volume":"49","author":"Lo","year":"2020","journal-title":"Chem. Soc. Rev."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"213548","DOI":"10.1016\/j.ccr.2020.213548","article-title":"Phthalocyanines as Contrast Agents for Photothermal Therapy","volume":"426","author":"Zheng","year":"2021","journal-title":"Coord. Chem. Rev."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1002\/chem.202002703","article-title":"Turning Photons into Drugs: Phthalocyanine-Based Photosensitizers as Efficient Photoantimicrobials","volume":"27","author":"Galstyan","year":"2021","journal-title":"Chem.-Eur. J."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1080\/02678292.2020.1861347","article-title":"Liquid-Crystalline Behaviour and Electrorheological Effect of Phthalocyanine-Based Ionic Liquid Crystals","volume":"48","author":"Reheman","year":"2021","journal-title":"Liq. Cryst."},{"key":"ref_45","first-page":"e202300856","article-title":"Silicon Phthalocyanines as Anti-Infectious, Antioxidant, and Anticancer Agents","volume":"8","author":"Yenilmez","year":"2023","journal-title":"Chem. Sel."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.eurpolymj.2017.02.042","article-title":"Polymer Composites with Photo-Responsive Phthalocyanine for Patterning in Color and Fluorescence","volume":"89","author":"Li","year":"2017","journal-title":"Eur. Polym. J."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1351\/pac199668071429","article-title":"Macrocyclic Functional Dyes: Applications to Optical Disk Media, Photochemical Hole Burning and Nonlinear Optics","volume":"68","author":"Seto","year":"1996","journal-title":"Pure Appl. Chem."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/(SICI)1099-1409(199710)1:4<385::AID-JPP42>3.0.CO;2-I","article-title":"Investigation of Phthalocyanine Catalysts for the Aerobic Synthesis of Meso-Substituted Porphyrins","volume":"1","author":"Ravikanth","year":"1997","journal-title":"J. Porphyr. Phthalocyanines"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"e202103223","DOI":"10.1002\/chem.202103223","article-title":"Direct Near Infrared Light\u2013Activatable Phthalocyanine Catalysts","volume":"28","author":"Katsurayama","year":"2022","journal-title":"Chem.-Eur. J."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"5725","DOI":"10.1039\/C8DT00198G","article-title":"Activating [4 + 4] Photoreactivity in the Solid-State: Via Complexation: From 9-(Methylaminomethyl)Anthracene to Its Silver(i) Complexes","volume":"47","author":"Spinelli","year":"2018","journal-title":"Dalton Trans."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s10847-018-0800-6","article-title":"Preparation, Characterization of New Co(II) and Cu(II) Phthalocyanines and Their Catalytic Performances in Aerobic Oxidation of Substituted Phenols","volume":"91","author":"Saka","year":"2018","journal-title":"J. Incl. Phenom. Macrocycl. Chem."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"11354","DOI":"10.1039\/D4DT01138D","article-title":"Synthesis, Characterization, DNA Interaction, Molecular Docking, and \u03b1-Amylase and \u03b1-Glucosidase Inhibition Studies of a Water Soluble Zn(Ii) Phthalocyanine","volume":"53","author":"Saka","year":"2024","journal-title":"Dalton Trans."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1080\/00958972.2024.2400573","article-title":"Synthesis of Phthalocyanine\/C3N4 Structures and Investigation of Photocatalytic Activities in the Oxidation Reaction of 4-Nitrophenol","volume":"78","author":"Saka","year":"2024","journal-title":"J. Coord. Chem."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"141757","DOI":"10.1016\/j.molstruc.2025.141757","article-title":"Synthesis of 1,2,4-Triazole Substituted Co(II) and Cu(II) Phthalocyanine Compounds and Investigation of Their Photocatalytic Activities in the Photochemical Degradation Reaction of 4-Nitrophenol","volume":"1334","author":"Avlar","year":"2025","journal-title":"J. Mol. Struct."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"4040165","DOI":"10.1155\/2016\/4040165","article-title":"Dispersive Liquid-Liquid Microextraction in the Analysis of Milk and Dairy Products: A Review","volume":"2016","author":"Quigley","year":"2016","journal-title":"J. Chem."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/19440049.2013.859742","article-title":"Simultaneous Determination of Sorbic and Benzoic Acids in Milk Products Using an Optimised Microextraction Technique Followed by Gas Chromatography","volume":"31","author":"Abedi","year":"2014","journal-title":"Food Addit. Contam. Part A"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.5740\/jaoacint.12-422","article-title":"A Dispersive Liquid-Liquid Microextraction Methodology for Copper(II) in Environmental Samples Prior to Determination Using Microsample Injection Flame Atomic Absorption Spectrometry","volume":"96","author":"Alothman","year":"2013","journal-title":"J. AOAC Int."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.chroma.2006.05.010","article-title":"Dispersive Liquid-Liquid Microextraction Combined with Gas Chromatography-Flame Photometric Detection. Very Simple, Rapid and Sensitive Method for the Determination of Organophosphorus Pesticides in Water","volume":"1123","author":"Berijani","year":"2006","journal-title":"J. Chromatogr. A"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ab.2008.05.008","article-title":"Determination of Trace Lead in Biological and Water Samples with Dispersive Liquid-Liquid Microextraction Preconcentration","volume":"380","author":"Liang","year":"2008","journal-title":"Anal. Biochem."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s00604-009-0162-2","article-title":"Speciation of As(III) and As(V) in Water Samples by Dispersive Liquid-Liquid Microextraction Separation and Determination by Graphite Furnace Atomic Absorption Spectrometry","volume":"166","author":"Liang","year":"2009","journal-title":"Microchim. Acta"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"119552","DOI":"10.1016\/j.saa.2021.119552","article-title":"Efficiency Enhancement of the Spectrophotometric Estimation of Cobalt in Waters and Pharmaceutical Preparations Using Dispersive Liquid\u2013Liquid Microextraction and Microcells with Long Optical Paths","volume":"253","author":"Alharthi","year":"2021","journal-title":"Spectrochim. Acta Part A Mol. Biomol. Spectrosc."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"106565","DOI":"10.1016\/j.microc.2021.106565","article-title":"Dispersive Liquid\u2013Liquid Microextraction of Multi-Elements in Seawater Followed by Inductively Coupled Plasma-Mass Spectrometric Analysis and Evaluation of Its Greenness","volume":"169","author":"Sajid","year":"2021","journal-title":"Microchem. J."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1080\/03067319.2020.1711891","article-title":"An Efficient Green Microextraction Method of Co and Cu in Environmental Samples Prior to Their Flame Atomic Absorption Spectrometric Detection","volume":"101","author":"Divrikli","year":"2021","journal-title":"Int. J. Environ. Anal. Chem."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"403","DOI":"10.22146\/ijc.88218","article-title":"A Univariate Optimization Strategy for Pre-Concentration of Cobalt(II) in Various Matrixes by a DLLME before Analysis Using FAAS","volume":"24","author":"Mehdi","year":"2024","journal-title":"Indones. J. Chem."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s10847-018-0780-6","article-title":"Spectrophotometric Determination of Hg(II) in Water Samples by Dispersive Liquid Liquid Microextraction with Use Ionic Liquid after Derivatization with a Water Soluble Fe(II) Phthalocyanine","volume":"90","author":"Biyiklioglu","year":"2018","journal-title":"J. Incl. Phenom. Macrocycl. Chem."},{"key":"ref_66","unstructured":"Perrin, D.D., and Armarego, W.L.F. (1989). Purification of Laboratory Chemicals, Pergamon Press. [2nd ed.]."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1021\/jo00294a032","article-title":"Synthesis and Characterization of Di-Disubstituted Phthalocyanines","volume":"55","author":"Young","year":"1990","journal-title":"J. Org. Chem."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/30\/12\/2548\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:49:59Z","timestamp":1760032199000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/30\/12\/2548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,11]]},"references-count":67,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2025,6]]}},"alternative-id":["molecules30122548"],"URL":"https:\/\/doi.org\/10.3390\/molecules30122548","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,11]]}}}