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Bioavailability of zinc depends on interactions with other food components. Phytates negatively affect this element\u2019s absorption, whereas proteins, peptides, and amino acids increase its bioavailability. It has been proven that organic forms of zinc are better absorbed than inorganic compounds, like zinc oxide and sulfate. Amino acid combinations with zinc can use amino acid transporters in the absorption process. Estimation of Zn bioavailability and bioaccessibility are based on in vivo and in vitro studies, each having their advantages and disadvantages. The current review aims to gather and summarize recent research on the dietary role of Zn, especially data on bioavailability from food substances promoting\/inhibiting absorption, and the latest methods for determining the level of bioavailability of this nutrient.<\/jats:p>","DOI":"10.3390\/molecules30132742","type":"journal-article","created":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T03:39:59Z","timestamp":1750909199000},"page":"2742","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Dietary Zn\u2014Recent Advances in Studies on Its Bioaccessibility and Bioavailability"],"prefix":"10.3390","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3330-1224","authenticated-orcid":false,"given":"Joanna","family":"Tokarczyk","sequence":"first","affiliation":[{"name":"Department of Food and Nutrition, Medical University of Lublin, 4a Chodzki Str., 20-093 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8749-9657","authenticated-orcid":false,"given":"Wojciech","family":"Koch","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition, Medical University of Lublin, 4a Chodzki Str., 20-093 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S14","DOI":"10.1017\/S0007114508006818","article-title":"Indicators of Zinc Status at the Population Level: A Review of the Evidence","volume":"99","author":"Gibson","year":"2008","journal-title":"Br. 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