{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T12:03:51Z","timestamp":1764936231416,"version":"build-2065373602"},"reference-count":25,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T00:00:00Z","timestamp":1757721600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Natural Sciences and Engineering Research Council of Canada (NSERC)","award":["RGPIN\/04320-2018"],"award-info":[{"award-number":["RGPIN\/04320-2018"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Two cholesterol-based liquid crystalline materials were synthesized by incorporating perfluorinated acyl chains of different lengths with the help of epichlorohydrin and copper(I)-mediated azide-alkyne 2+3 dipolar cycloaddition chemistries. These materials were characterized by differential scanning calorimetry, cross-polarized optical microscopy and powder X-ray diffraction. The compound with the longer perfluorinated chain exhibited a smectic A (SmA) phase as confirmed by XRD and POM, while the shorter-chain derivative exhibited diffraction peaks suggestive of both simple SmA* ordering as well as lamellar solid phase exhibiting multilayer ordering.<\/jats:p>","DOI":"10.3390\/molecules30183731","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T10:51:33Z","timestamp":1757933493000},"page":"3731","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Synthesis and Characterization of Cholesterol-Based Liquid Crystals Linked with Perfluorinated Alkyl Chains"],"prefix":"10.3390","volume":"30","author":[{"given":"Austin","family":"Che","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9453-5898","authenticated-orcid":false,"given":"Carson O.","family":"Zellmann-Parrotta","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Homayoun","family":"Ghaseminezhad","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Duong","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1362-3031","authenticated-orcid":false,"given":"Vance E.","family":"Williams","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang-Chun","family":"Ling","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Albuquerque, H.M.T., Santos, C.M.M., and Silva, A.M.S. 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