{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T09:25:34Z","timestamp":1767345934589,"version":"3.48.0"},"reference-count":74,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Union Horizon 2020 Research and Innovation","doi-asserted-by":"publisher","award":["872233"],"award-info":[{"award-number":["872233"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Zein (ZP) is the major storage protein of corn (maize). It is safe, biodegradable, edible, and characterized by unique self-assembly properties. These properties were exploited to prepare ZP microcapsules filled with soybean oil (SO) by ultrasound-assisted emulsification of oil-in-water (o\/w) dispersions under optimal experimental conditions. The morphology and stability of o\/w ZP\/SO microcapsules were investigated by optical spectroscopy (electronic circular dichroism and fluorescence) and dynamic light scattering, as well as bright-field, laser confocal fluorescence, and scanning electron microscopies. The results showed that ZP formed a stable protein shell protecting the inner oily phase from diffusion of the confined compounds. It was also found that ZP\/SO microcapsules, stored under suitable conditions, could be redissolved in water, maintaining their spherical morphology. Proof-of-principle studies on the inclusion and release of curcumin, a very active anti-inflammatory and nutraceutical substance, from ZP\/SO microcapsules under temperature and pH stimuli are also reported.<\/jats:p>","DOI":"10.3390\/molecules31010153","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T09:18:56Z","timestamp":1767345536000},"page":"153","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Remarkable Properties of Oil-in-Water Zein Protein Microcapsules"],"prefix":"10.3390","volume":"31","author":[{"given":"Alessandra","family":"Quarta","sequence":"first","affiliation":[{"name":"Department of Chemical Science and Technologies, University of Rome Tor Vergata, Via della Ricerca Scientifica 1, 00133 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Del Balzo","sequence":"additional","affiliation":[{"name":"Department of Chemical Science and Technologies, University of Rome Tor Vergata, Via della Ricerca Scientifica 1, 00133 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5391-5069","authenticated-orcid":false,"given":"Francesca","family":"Cavalieri","sequence":"additional","affiliation":[{"name":"Department of Chemical Science and Technologies, University of Rome Tor Vergata, Via della Ricerca Scientifica 1, 00133 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1823-5337","authenticated-orcid":false,"given":"Raffaella","family":"Lettieri","sequence":"additional","affiliation":[{"name":"Department of Chemical Science and Technologies, University of Rome Tor Vergata, Via della Ricerca Scientifica 1, 00133 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9364-7441","authenticated-orcid":false,"given":"Mariano","family":"Venanzi","sequence":"additional","affiliation":[{"name":"Department of Chemical Science and Technologies, University of Rome Tor Vergata, Via della Ricerca Scientifica 1, 00133 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1039\/C9SM01634A","article-title":"Fabrication and application of complex microcapsules: A review","volume":"16","author":"Bah","year":"2020","journal-title":"Soft Matter"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Ariaudo, D., Cavalieri, F., Rinaldi, A., Aguilera, A., Lopez, M., Perez, H.G., Felipe, A., del Carmen Dominguez, M., Ruiz, O., and Martinez, G. 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