{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:20:16Z","timestamp":1790666416650,"version":"4.1.0"},"reference-count":56,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002383","name":"King Saud University","doi-asserted-by":"publisher","award":["ORF-2026-801"],"award-info":[{"award-number":["ORF-2026-801"]}],"id":[{"id":"10.13039\/501100002383","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Jacquemontia pentantha (Jacq.) G. Don. (Convolvulaceae): This is a plant with rich ethnobotanical uses, but its essential oil (EO) composition and overall biological properties remain largely uninvestigated. In this research, the J. pentantha EO (JPEO) is characterized in a thorough manner, with an evaluation of its in vitro antioxidant, antimicrobial, and cytotoxic properties, aiming to provide scientific support for ethnobotanical uses, as well as the definition of new potentialities. The EOs were isolated from the aerial part of the plant via hydrodistillation, and a qualitative analysis of the components was carried out via GC\u2013MS. The biological properties were investigated by means of standard in vitro assays: namely, DPPH and ABTS for the measurement of antioxidant activity, the disk diffusion technique, and the microbroth dilution assay for the evaluation of antimicrobial activity against six bacterial species, as well as for the assessment of the activity against five species of Candida fungi, whereas the cytotoxic activity against MCF-7 and HepG2 cells was assessed using the MTT assay. Preliminary characterization of the EOs via GC\/MS revealed a particular \u201cchemical profile\u201d with a high concentration of himachalene-type sesquiterpenes, namely, \u03b2-himachalene (6.47%) and (+)-\u03b1-himachalene (6.46%), together with phenolic monoterpenoids. The EOs showed significant antioxidant activity (IC50 = 172.41 and 378.94 \u00b5g\/mL, respectively), high phenolic content (97.34 mg GAE\/g), and significant antibacterial activity (MIC = 4.68 \u00b5g\/mL), especially against Pseudomonas aeruginosa, as well as against Candida albicans (MFC = 3.90 \u00b5g\/mL), together with dose-dependent cytotoxic effects on the two cell lines, with IC50 = 161.62 and 151.87 \u00b5g\/mL, respectively. This research indicates that the EO of this plant is a potential source of a certain \u201cchemical profile\u201d with noteworthy antibacterial and cytotoxic properties, thus providing scientific support for its ethnobotanical use and highlighting its particular potential for developing pharmaceutical agents against infections and cancer.<\/jats:p>","DOI":"10.3390\/molecules31020296","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T11:01:14Z","timestamp":1768388474000},"page":"296","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Chemical Composition, Antimicrobial, Antioxidant, and Anticancer Activities of Jacquemontia pentantha Essential Oils"],"prefix":"10.3390","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8847-323X","authenticated-orcid":false,"given":"Noorah A.","family":"Alkubaisi","sequence":"first","affiliation":[{"name":"Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mashail Fahad","family":"Alsayed","sequence":"additional","affiliation":[{"name":"Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hissah Abdulrahman","family":"Alodaini","sequence":"additional","affiliation":[{"name":"Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5328-6239","authenticated-orcid":false,"given":"Fuad","family":"Alanazi","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 12372, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8600-4118","authenticated-orcid":false,"given":"Abdulhadi M.","family":"Abdulwahed","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 12372, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6970-5207","authenticated-orcid":false,"given":"Ibrahim M.","family":"Aziz","sequence":"additional","affiliation":[{"name":"Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Bunse, M., Daniels, R., Gr\u00fcndemann, C., Heilmann, J., Kammerer, D.R., Keusgen, M., Lindequist, U., Melzig, M.F., Morlock, G.E., and Schulz, H. (2022). Essential oils as multicomponent mixtures and their potential for human health and well-being. Front. Pharmacol., 13.","DOI":"10.3389\/fphar.2022.956541"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"El Boukhari, R., and Fatimi, A. (2025). The Innovative potential of key mentha species: An assessment based on patent analysis. Biol. Life Sci. Forum, 39.","DOI":"10.3390\/blsf2024039005"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"El-Saadony, M.T., Saad, A.M., Mohammed, D.M., Korma, S.A., Alshahrani, M.Y., Ahmed, A.E., Ibrahim, E.H., Salem, H.M., Alkafaas, S.S., and Saif, A.M. (2025). Medicinal plants: Bioactive compounds, biological activities, combating multidrug-resistant microorganisms, and human health benefits-a comprehensive review. Front. Immunol., 16.","DOI":"10.3389\/fimmu.2025.1491777"},{"key":"ref_4","first-page":"568","article-title":"Bioactive compounds and biological activities of Jacquemontia Pentanthos (Jacq.) G. Don.: A Phytochemical and pharmacological study","volume":"2","author":"Modi","year":"2025","journal-title":"Int. J. Sci. Res. Technol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"718","DOI":"10.5530\/pj.2019.11.114","article-title":"Investigation of secondary metabolites and cytotoxicity of Jacquemontia pentantha (Jacq.)","volume":"11","author":"Eskander","year":"2019","journal-title":"Pharmacogn. J."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"3314","DOI":"10.1080\/14786419.2019.1689500","article-title":"Plants adapted to arid areas: Specialized metabolites","volume":"35","author":"Zahedi","year":"2021","journal-title":"Nat. Prod. Res."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.sajb.2017.12.013","article-title":"An inventory of vhaven\u1e13a useful plants","volume":"122","author":"Magwede","year":"2019","journal-title":"S. Afr. J. Bot."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.biopha.2022.113559","article-title":"Peppermint essential oil: Its phytochemistry, biological activity, pharmacological effect and application","volume":"154","author":"Zhao","year":"2022","journal-title":"Biomed. Pharmacother."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Hudz, N., Kobylinska, L., Pokajewicz, K., Hor\u010dinov\u00e1 Sedl\u00e1\u010dkov\u00e1, V., Fedin, R., Voloshyn, M., Myskiv, I., Brindza, J., Wieczorek, P.P., and Lipok, J. (2023). Mentha piperita: Essential oil and extracts, their biological activities, and perspectives on the development of new medicinal and cosmetic products. Molecules, 28.","DOI":"10.3390\/molecules28217444"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1080\/10408398.2023.2296991","article-title":"Peppermint and menthol: A review on their biochemistry, pharmacological activities, clinical applications, and safety considerations","volume":"65","author":"Kazemi","year":"2025","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Ailli, A., Handaq, N., Touijer, H., Gourich, A.A., Drioiche, A., Zibouh, K., Eddamsyry, B., El Makhoukhi, F., Mouradi, A., and Bin Jardan, Y.A. (2023). Phytochemistry and biological activities of essential oils from six aromatic medicinal plants with cosmetic properties. Antibiotics, 12.","DOI":"10.3390\/antibiotics12040721"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Bibow, A., and Oleszek, W. (2024). Essential oils as potential natural antioxidants, antimicrobial, and antifungal agents in active food packaging. Antibiotics, 13.","DOI":"10.3390\/antibiotics13121168"},{"key":"ref_13","first-page":"1","article-title":"First report on the phytochemical, nutritional and antioxidant potential of Jacquemontia pentanthos, a key plant species from Kerala, India","volume":"12","author":"Parvathy","year":"2025","journal-title":"Plant Sci. Today"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"D1373","DOI":"10.1093\/nar\/gkac956","article-title":"PubChem 2023 update","volume":"51","author":"Kim","year":"2023","journal-title":"Nucleic Acids Res."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"5266","DOI":"10.1021\/acs.jafc.7b01834","article-title":"Identification of indole diterpenes in Ipomoea asarifolia and Ipomoea muelleri, plants tremorgenic to livestock","volume":"65","author":"Lee","year":"2017","journal-title":"J. Agric. Food Chem."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Salamatullah, A.M. (2022). Convolvulus arvensis: Antioxidant, antibacterial, and antifungal properties of chemically profiled essential oils: An approach against nosocomial infections. Life, 12.","DOI":"10.3390\/life12122138"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"151898","DOI":"10.1016\/j.flora.2021.151898","article-title":"Morphology and phytochemistry of Teucrium chamaedrys L. (Lamiaceae) cultivated at the Ghirardi Botanic Garden (Lombardy, Northern Italy)","volume":"282","author":"Giuliani","year":"2021","journal-title":"Flora"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.sajb.2022.12.018","article-title":"Insight into micromorphology and phytochemistry of Lavandula angustifolia Mill. from Italy","volume":"153","author":"Giuliani","year":"2023","journal-title":"S. Afr. J. Bot."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/s11101-020-09671-y","article-title":"Thujone, a widely debated volatile compound: What do we know about it?","volume":"19","year":"2020","journal-title":"Phytochem. Rev."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jep.2016.07.048","article-title":"Aqueous extract from Ipomoea asarifolia (Convolvulaceae) leaves and its phenolic compounds have anti-inflammatory activity in murine models of edema, peritonitis and air-pouch inflammation","volume":"192","author":"Furtado","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"399","DOI":"10.4314\/bcse.v36i2.13","article-title":"Chemical composition and anti-inflammatory activity of essential oils from resin of Commiphora species","volume":"36","author":"Dinku","year":"2022","journal-title":"Bull. Chem. Soc. Ethiop."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"9004014","DOI":"10.1155\/2022\/9004014","article-title":"Beta-caryophyllene as an antioxidant, anti-inflammatory and re-epithelialization activities in a rat skin wound excision model","volume":"2022","author":"Gushiken","year":"2022","journal-title":"Oxidative Med. Cell. Longev."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Dickson, K., Scott, C., White, H., Zhou, J., Kelly, M., and Lehmann, C. (2023). Antibacterial and analgesic properties of beta-caryophyllene in a murine urinary tract infection model. Molecules, 28.","DOI":"10.3390\/molecules28104144"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Mendoza-Almanza, G., Esparza-Ibarra, E.L., Ayala-Luj\u00e1n, J.L., Mercado-Reyes, M., Godina-Gonz\u00e1lez, S., Hern\u00e1ndez-Barrales, M., and Olmos-Soto, J. (2020). The cytocidal spectrum of Bacillus thuringiensis toxins: From insects to human cancer cells. Toxins, 12.","DOI":"10.3390\/toxins12050301"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"119316","DOI":"10.1016\/j.jep.2024.119316","article-title":"The jalap roots: A herbal legacy from the neotropics to the world","volume":"341","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.sjbs.2020.11.013","article-title":"Medicinal plants used in Jeddah, Saudi Arabia: Phytochemical screening","volume":"28","author":"Alqethami","year":"2021","journal-title":"Saudi J. Biol. Sci."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1021\/acs.jnatprod.1c00649","article-title":"Phytochemical investigation of the roots of Ipomoea asarifolia and Antiproliferative activity of the isolated compounds against multiple myeloma cells","volume":"85","author":"Saraux","year":"2021","journal-title":"J. Nat. Prod."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Wo\u0142osiak, R., Dru\u017cy\u0144ska, B., Derewiaka, D., Piecyk, M., Majewska, E., Ciecierska, M., Worobiej, E., and Pakosz, P. (2021). Verification of the conditions for determination of antioxidant activity by ABTS and DPPH assays\u2014A practical approach. Molecules, 27.","DOI":"10.3390\/molecules27010050"},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Baliyan, S., Mukherjee, R., Priyadarshini, A., Vibhuti, A., Gupta, A., Pandey, R.P., and Chang, C.-M. (2022). Determination of antioxidants by DPPH radical scavenging activity and quantitative phytochemical analysis of Ficus religiosa. Molecules, 27.","DOI":"10.3390\/molecules27041326"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"100984","DOI":"10.1016\/j.eujim.2019.100984","article-title":"Antioxidant activity guided isolation of a coumarin compound from Ipomoea pes-caprea (Convolvulaceae) leaves acetone extract and its biological and molecular docking studies","volume":"32","author":"Alagesan","year":"2019","journal-title":"Eur. J. Integr. Med."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Gulcin, \u0130., and Alwasel, S.H. (2023). DPPH radical scavenging assay. Processes, 11.","DOI":"10.3390\/pr11082248"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.biotechadv.2018.11.013","article-title":"Antibiotic resistance in Pseudomonas aeruginosa: Mechanisms and alternative therapeutic strategies","volume":"37","author":"Pang","year":"2019","journal-title":"Biotechnol. Adv."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Hu, M., and Chua, S.L. (2025). Antibiotic-Resistant Pseudomonas aeruginosa: Current challenges and emerging alternative therapies. Microorganisms, 13.","DOI":"10.3390\/microorganisms13040913"},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Hulankova, R. (2024). Methods for Determination of antimicrobial activity of essential oils in vitro\u2014A review. Plants, 13.","DOI":"10.20944\/preprints202407.2507.v1"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"3012462","DOI":"10.1155\/2016\/3012462","article-title":"Antimicrobial properties of plant essential oils against human pathogens and their mode of action: An updated review","volume":"2016","author":"Swamy","year":"2016","journal-title":"Evid.-Based Complement. Altern. Med."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1080\/15287394.2021.1999875","article-title":"Risk assessment of in vitro cytotoxicity, antioxidant and antimicrobial activities of Mentha piperita L. essential oil","volume":"85","author":"Silva","year":"2022","journal-title":"J. Toxicol. Environ. Health Part A"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.32350\/cto.32.01","article-title":"Antioxidant and Antimicrobial activity of Cuscuta reflexa ROXB. and few members of family Convolvulaceae","volume":"3","author":"Noshad","year":"2023","journal-title":"Curr. Trends OMICS"},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Iskandar, K., Ahmed, N., Paudyal, N., Ruiz Alvarez, M.-J., Balasubramani, S.P., Saadeh, D., Ullah Baig, S., Sami, H., Hammoudi Halat, D., and Pavlovi\u0107, N. (2025). Essential Oils as antimicrobial agents against WHO Priority bacterial pathogens: A strategic review of in vitro clinical efficacy, innovations and research gaps. Antibiotics, 14.","DOI":"10.3390\/antibiotics14121250"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1007\/s12223-020-00787-4","article-title":"Phenolic\u2013OH group is crucial for the antifungal activity of terpenoids via disruption of cell membrane integrity","volume":"65","author":"Konuk","year":"2020","journal-title":"Folia Microbiol."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Franconi, I., and Lupetti, A. (2023). In vitro susceptibility tests in the context of antifungal resistance: Beyond minimum inhibitory concentration in Candida spp.. J. Fungi, 9.","DOI":"10.3390\/jof9121188"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Hrichi, S., Cha\u00e2bane-Banaoues, R., Alibrando, F., Altemimi, A.B., Babba, O., Majdoub, Y.O.E., Nasri, H., Mondello, L., Babba, H., and Mighri, Z. (2022). Chemical composition, antifungal and anti-biofilm activities of volatile fractions of Convolvulus althaeoides L. roots from Tunisia. Molecules, 27.","DOI":"10.3390\/molecules27206834"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3897\/pharmacia.71.e119384","article-title":"Antifungal activity and hair growth stimulation of purple sweet potato leaf fraction (Ipomoea batatas (L.) Lamk) and its molecular mechanism through androgen receptor inhibition","volume":"71","author":"Armadany","year":"2024","journal-title":"Pharmacia"},{"key":"ref_43","first-page":"1","article-title":"Evaluation of the Antimicrobial activity of 20 essential oils and their combinations on bacterial and fungal strains","volume":"17","author":"Ezzariga","year":"2025","journal-title":"Cureus"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.56499\/jppres24.2115_13.5.1400","article-title":"Chemical composition, antioxidant capacity, and anticancer activity of the essential oil from aerial parts of Convolvulus lanatus Vahl","volume":"13","author":"Fahad","year":"2025","journal-title":"J. Pharm. Pharmacogn. Res."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1089\/jmf.2012.0050","article-title":"Convolvulus galaticus, Crocus antalyensis, and Lilium candidum extracts show their antitumor activity through induction of p53-mediated apoptosis on human breast cancer cell line MCF-7 cells","volume":"15","author":"Tokgun","year":"2012","journal-title":"J. Med. Food"},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Hendel, N., Sarri, D., Sarri, M., Napoli, E., Palumbo Piccionello, A., and Ruberto, G. (2024). Phytochemical Analysis and antioxidant and antifungal activities of powders, methanol extracts, and essential oils from Rosmarinus officinalis L. and Thymus ciliatus Desf. Benth. Int. J. Mol. Sci., 25.","DOI":"10.3390\/ijms25147989"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"15593258211004739","DOI":"10.1177\/15593258211004739","article-title":"Phytochemical analysis, antioxidant and antimicrobial screening of Seriphidium oliverianum plant extracts","volume":"19","author":"Abbas","year":"2021","journal-title":"Dose-Response"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1021\/jf025916z","article-title":"Apple peels as a value-added food ingredient","volume":"51","author":"Wolfe","year":"2003","journal-title":"J. Agric. Food Chem."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.foodchem.2005.05.024","article-title":"Antioxidant activities of Sechium edule (Jacq.) Swartz extracts","volume":"97","author":"Ordonez","year":"2006","journal-title":"Food Chem."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.indcrop.2018.07.051","article-title":"Variation in chemical composition of Eucalyptus globulus essential oil under phenological stages and evidence synergism with antimicrobial standards","volume":"124","author":"Salem","year":"2018","journal-title":"Ind. Crops Prod."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"5249534","DOI":"10.1155\/2016\/5249534","article-title":"Synergistic interaction of methanol extract from Canarium odontophyllum Miq. Leaf in combination with oxacillin against methicillin-resistant Staphylococcus aureus (MRSA) ATCC 33591","volume":"2016","author":"Basri","year":"2016","journal-title":"Int. J. Microbiol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"125","DOI":"10.2147\/IDR.S394600","article-title":"Synergistic Antibacterial potential of greenly synthesized silver nanoparticles with fosfomycin against some nosocomial bacterial pathogens","volume":"16","author":"Aljeldah","year":"2022","journal-title":"Infect. Drug Resist."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1128\/AAC.46.5.1455-1461.2002","article-title":"Potato dextrose agar antifungal susceptibility testing for yeasts and molds: Evaluation of phosphate effect on antifungal activity of CMT-3","volume":"46","author":"Liu","year":"2002","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref_54","first-page":"4045013","article-title":"In vitro effect of Cinnamomum zeylanicum Blume essential oil on Candida spp. involved in oral infections. Evid.-Based Complement","volume":"2018","author":"Rangel","year":"2018","journal-title":"Altern. Med."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Tian, M., Wu, X., Lu, T., Zhao, X., Wei, F., Deng, G., and Zhou, Y. (2020). Phytochemical analysis, antioxidant, antibacterial, cytotoxic, and enzyme inhibitory activities of Hedychium flavum rhizome. Front. Pharmacol., 11.","DOI":"10.3389\/fphar.2020.572659"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.lwt.2013.01.024","article-title":"Antioxidants in volatile Maillard reaction products: Identification and interaction","volume":"53","author":"Yu","year":"2013","journal-title":"LWT-Food Sci. Technol."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/31\/2\/296\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T11:02:16Z","timestamp":1768388536000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/31\/2\/296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,14]]},"references-count":56,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,1]]}},"alternative-id":["molecules31020296"],"URL":"https:\/\/doi.org\/10.3390\/molecules31020296","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,14]]}}}